SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

H2R328

- H2R328_PANTR

UniProt

H2R328 - H2R328_PANTR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Nuclear receptor binding SET domain protein 1

Gene
NSD1
Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotations

GO - Molecular functioni

  1. chromatin binding Source: Ensembl
  2. histone-lysine N-methyltransferase activity Source: InterPro
  3. transcription cofactor activity Source: Ensembl
  4. zinc ion binding Source: Ensembl

GO - Biological processi

  1. gastrulation with mouth forming second Source: Ensembl
  2. positive regulation of transcription, DNA-templated Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotation, ReceptorImported, Transferase

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor binding SET domain protein 1Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:NSD1Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
ProteomesiUP000002277: Chromosome 5

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotations

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation
Contains SET domain.SAAS annotations
Contains post-SET domain.SAAS annotations

Keywords - Domaini

Zinc-fingerSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00740000114921.
KOiK15588.
OMAiECRTGIH.
OrthoDBiEOG7Z69BG.
TreeFamiTF329088.

Family and domain databases

Gene3Di3.30.40.10. 3 hits.
InterProiIPR006560. AWS.
IPR003616. Post-SET_dom.
IPR000313. PWWP_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00628. PHD. 1 hit.
PF00855. PWWP. 2 hits.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00249. PHD. 5 hits.
SM00508. PostSET. 1 hit.
SM00293. PWWP. 2 hits.
SM00184. RING. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 3 hits.
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50812. PWWP. 2 hits.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 2 hits.
PS50016. ZF_PHD_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H2R328-1 [UniParc]FASTAAdd to Basket

« Hide

MDQTCELPRR NCLLPFSNPV NLDAPEDKDS PFGNGQSNFS EPLNGCTMQL     50
STVSGTSQNA YGQDSPSCYI PLRRLQDLAS MINVEYLNGS ADGSESFQDP 100
EKSDSRAQTP IVCTSLSPGG PTALAMKQEP SCNNSPELQV KVTKTIKNGF 150
LHFENFTCVD DADVDSEMDP EQPVTEDESI EEIFEETQTN ATCNYETKSE 200
NGVKVAMGSE QDSTPESRHG AVKSPFLPLA PQTETQKNKQ RNEVDGSNEK 250
AALLPAPFSL GDTNITIEEQ LNSINLSFQD DPDSSTSTLG NMLELPGTSS 300
SSTSQELPFC QPKKKSTPLK YEVGDLIWAK FKRRPWWPCR ICSDPLINTH 350
SKMKVSNRRP YRQYYVEAFG DPSERAWVAG KAIVMFEGRH QFEELPVLRR 400
RGKQKEKGYR HKVPQKILSK WEASVGLAEQ YDVPKGSKNR KCIPGSIKLD 450
SEEDMPFEDC TNDPESEHDL LLNGCLKSLA FDSEHSADEK EKPCAKSRAR 500
KSSDNPKRTS VKKGHIQFEA HKDERRGKIP ENLGLNFISG DISDTQASNE 550
LSRIANSLTG SNTAPGSFLF SSCGKNTAKK EFETSNGDSL LGLPEGALIS 600
KCSREKNKPQ RSLVCGSKVK LCYIGAGDEE KRSDSISICT TSDDGSSDLD 650
PIEHSSESDN SVLEIPDAFD RTENMLSMQK NEKIKYSRFA ATNTRVKAKQ 700
KPLISNSHTD HLMGCTKSAE PGTETSQVNL SDLKASTLVH KPQSDFTNDA 750
LSPKFNMSSS ISSENSLIKG GAANQALLHS KSKQPKFRSI KCKHKENPVM 800
VEPPVINEEC SLKCCSSDTK GSPLASISKS GKVDGLKLLN NMHEKTRDSS 850
DIETAVVKHV LSELKELSYR SLGEDVSDSG TSKPSKPLLF SSASSQNHIP 900
IEPDYKFSTL LMMLKDMHDS KTKEQRLMTA QNLVSYRSPG RGDCSTNSPV 950
GVSKVLVSGG STHNSEKKGD GTQNSANPSP SGGDSALSGE LSASLPGLVS 1000
DKRDLPASGK SRSDCVTRRN CGRSKPSSKL RDAFSAQMVK NTVNRKALKT 1050
ERKRKLNQLP SVTLDAVLQG DREHGGSLRG GAEDPSKEDP LQIMGHLTSE 1100
DGDHFSDVHF DSKVKQSDPG KISEKGLSFE NGKGPELDSV MNSENDELNG 1150
VNQVVPKKRW QRLNQRRTKP RKRMNRFKEK ENSECAFRVL LPSDPVQEGR 1200
DEFPEHRTPP SASILEEPLT EQNHADCLDS VGPRLNVCDK SSASIGDMEK 1250
EPGIPSLTPQ AELPEPAVRS EKKRLRKPSK WLLEYTEEYD QIFAPKKKQK 1300
KVQEQVHKVS SRCEEESLLA RGRSSAQNKQ VDENSLISTK EEPPVLEREA 1350
PFLEGPLAQS ELGGGHAELP QLTLSVPVAP EVSPRPALES EELLVKTPGN 1400
YESKRQRKPT KKLLESNDLD PGFMPKKGDL GLSKKCYEAG HLENGITESC 1450
ATSYSKDFGG GTTKIFDKPR KRKRQRHAAA KMQCKKVKND DSSKEIPGSE 1500
GELMPHRTAT SPKETVEEGV EHDPGMPASK KMQGERGGGA ALKENVCQNC 1550
EKLGELLLCE AQCCGAFHLE CLGLTEMPRG KFICNECRTG IHTCFVCKQS 1600
GEDVKRCLLP LCGKFYHEEC VQKYPPTVMQ NKGFRCSLHI CITCHAANPA 1650
NVSASKGRLM RCVRCPVAYH ANDFCLAAGS KILASNSIIC PNHFTPRRGC 1700
RNHEHVNVSW CFVCSEGGSL LCCDSCPAAF HRECLNIDIP EGNWYCNDCK 1750
AGKKPHYREI VWVKVGRYRW WPAEICHPRA VPSNIDKMRH DVGEFPVLFF 1800
GSNDYLWTHQ ARVFPYMEGD VSSKDKMGKG VDGTYKKALQ EAAARFEELK 1850
AQKELRQLQE DRKNDKKPPP YKHIKVNRPI GRVQIFTADL SEIPRCNCKA 1900
TDENPCGIDS ECINRMLLYE CHPTVCPAGG RCQNQCFSKR QYPEVEIFRT 1950
LQRGWGLRTK TDIKKGEFVN EYVGELIDEE ECRARIRYAQ EHDITNFYML 2000
TLDKDRIIDA GPKGNYARFM NHCCQPNCET QKWSVNGDTR VGLFALSDIK 2050
AGTELTFNYN LECLGNGKTV CKCGAPNCSG FLGVRPKNQP IATEEKSKKF 2100
KKKQQGKRRT QGEITKERED ECFSCGDAGQ LVSCKKPGCP KVYHADCLNL 2150
TKRPAGKWEC PWHQCDICGK EAASFCEMCP SSFCKQHREG MLFISKLDGR 2200
LSCTEHDPCG PNPLEPGEIR EYVPPPVPLP PGPSTHLAEQ STGMAAQAPK 2250
MSDKPPADTN QTLSLSKKAL AGTCQRPLLP ERPLERTDSR PQPLDKVRDL 2300
AGSGTKSQSL VSSQRPLDRP PAVAGPRPQL SDKPSPVTSP SSSPSVRSQP 2350
LERPLGTADP RLDKSIGAAS PRPQSLEKTP VPTGLRLPPP DRLLITSSPK 2400
PQTSDRPTDK PHASLSQRLP PPEKVLSAVV QTLVAKEKAL RPVDQNTQSK 2450
NRAALVMDLI DLTPRQKERA ASPHEVTPQA DEKMPVLESS SWPASKGLGH 2500
MPRAVEKGCV SDPLQTSGKA AAPSEDPWQA VKSLTQARLL SQPPAKAFLY 2550
EPTTQASGRA SAGAEQTPGP LSQSLGLVKQ AKQMVGGQQL PALAAKSGQS 2600
FRSLGKAPAS LPTEEKKLVT TEQSPWALGK ASSRAGLWPI VAGQTLAQSC 2650
WSAGSTQTLA QTCWSLGRGQ DPKPEQNTLP ALNQAPSSHK CAESEQK 2697
Length:2,697
Mass (Da):296,787
Last modified:March 21, 2012 - v1
Checksum:i602F82967C45359E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACZ03043090 Genomic DNA. No translation available.
AACZ03043091 Genomic DNA. No translation available.
AACZ03043092 Genomic DNA. No translation available.
AACZ03043093 Genomic DNA. No translation available.
AACZ03043094 Genomic DNA. No translation available.
AACZ03043095 Genomic DNA. No translation available.
AACZ03043096 Genomic DNA. No translation available.
AACZ03043097 Genomic DNA. No translation available.
AACZ03043098 Genomic DNA. No translation available.
AACZ03043099 Genomic DNA. No translation available.
AACZ03043100 Genomic DNA. No translation available.
AACZ03043101 Genomic DNA. No translation available.
AACZ03043102 Genomic DNA. No translation available.
AACZ03043103 Genomic DNA. No translation available.
AACZ03043104 Genomic DNA. No translation available.
AACZ03043105 Genomic DNA. No translation available.
AACZ03043106 Genomic DNA. No translation available.
AACZ03043107 Genomic DNA. No translation available.
AACZ03043108 Genomic DNA. No translation available.
GABD01002572 mRNA. Translation: JAA30528.1.
GABE01004826 mRNA. Translation: JAA39913.1.
RefSeqiXP_527132.2. XM_527132.3.

Genome annotation databases

EnsembliENSPTRT00000042784; ENSPTRP00000044805; ENSPTRG00000017575.
GeneIDi471754.
KEGGiptr:471754.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACZ03043090 Genomic DNA. No translation available.
AACZ03043091 Genomic DNA. No translation available.
AACZ03043092 Genomic DNA. No translation available.
AACZ03043093 Genomic DNA. No translation available.
AACZ03043094 Genomic DNA. No translation available.
AACZ03043095 Genomic DNA. No translation available.
AACZ03043096 Genomic DNA. No translation available.
AACZ03043097 Genomic DNA. No translation available.
AACZ03043098 Genomic DNA. No translation available.
AACZ03043099 Genomic DNA. No translation available.
AACZ03043100 Genomic DNA. No translation available.
AACZ03043101 Genomic DNA. No translation available.
AACZ03043102 Genomic DNA. No translation available.
AACZ03043103 Genomic DNA. No translation available.
AACZ03043104 Genomic DNA. No translation available.
AACZ03043105 Genomic DNA. No translation available.
AACZ03043106 Genomic DNA. No translation available.
AACZ03043107 Genomic DNA. No translation available.
AACZ03043108 Genomic DNA. No translation available.
GABD01002572 mRNA. Translation: JAA30528.1 .
GABE01004826 mRNA. Translation: JAA39913.1 .
RefSeqi XP_527132.2. XM_527132.3.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSPTRT00000042784 ; ENSPTRP00000044805 ; ENSPTRG00000017575 .
GeneIDi 471754.
KEGGi ptr:471754.

Organism-specific databases

CTDi 64324.

Phylogenomic databases

GeneTreei ENSGT00740000114921.
KOi K15588.
OMAi ECRTGIH.
OrthoDBi EOG7Z69BG.
TreeFami TF329088.

Family and domain databases

Gene3Di 3.30.40.10. 3 hits.
InterProi IPR006560. AWS.
IPR003616. Post-SET_dom.
IPR000313. PWWP_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF00628. PHD. 1 hit.
PF00855. PWWP. 2 hits.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00570. AWS. 1 hit.
SM00249. PHD. 5 hits.
SM00508. PostSET. 1 hit.
SM00293. PWWP. 2 hits.
SM00184. RING. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
SUPFAMi SSF57903. SSF57903. 3 hits.
PROSITEi PS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50812. PWWP. 2 hits.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 2 hits.
PS50016. ZF_PHD_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Initial sequence of the chimpanzee genome and comparison with the human genome."
    Chimpanzee sequencing and analysis consortium
    Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  3. "De novo assembly of the reference chimpanzee transcriptome from NextGen mRNA sequences."
    Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.
    Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Skeletal muscleImported and SkinImported.

Entry informationi

Entry nameiH2R328_PANTR
AccessioniPrimary (citable) accession number: H2R328
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: July 9, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi