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H2R1P1

- H2R1P1_PANTR

UniProt

H2R1P1 - H2R1P1_PANTR

Protein
Submitted name:

SET domain, bifurcated 2

Gene

SETDB2

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (21 Mar 2012)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. histone methyltransferase activity (H3-K9 specific) Source: Ensembl
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. chromosome segregation Source: Ensembl
    2. mitotic nuclear division Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    SET domain, bifurcated 2Imported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:SETDB2Imported
    OrganismiPan troglodytes (Chimpanzee)Imported
    Taxonomic identifieri9598 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
    ProteomesiUP000002277: Chromosome 13

    Subcellular locationi

    Nucleus UniRule annotation
    Nucleus By similarity

    GO - Cellular componenti

    1. chromosome Source: UniProtKB-KW
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    ChromosomeSAAS annotation, NucleusUniRule annotationSAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SET domain.UniRule annotation
    Contains 1 pre-SET domain.UniRule annotation
    Contains SET domain.SAAS annotation
    Contains pre-SET domain.SAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117355.
    KOiK11421.
    OMAiKCHFQRR.
    OrthoDBiEOG7ZD1TG.
    TreeFamiTF106411.

    Family and domain databases

    Gene3Di3.30.890.10. 1 hit.
    InterProiIPR016177. DNA-bd_dom.
    IPR001739. Methyl_CpG_DNA-bd.
    IPR007728. Pre-SET_dom.
    IPR001214. SET_dom.
    [Graphical view]
    PfamiPF01429. MBD. 1 hit.
    PF05033. Pre-SET. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view]
    SMARTiSM00317. SET. 1 hit.
    [Graphical view]
    SUPFAMiSSF54171. SSF54171. 1 hit.
    PROSITEiPS50982. MBD. 1 hit.
    PS50867. PRE_SET. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H2R1P1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGEKNGDAKT FWMELEDDGK VDFIFEQVQN VLQSLKQKIK DGSATNKEYI    50
    QAMILVNEAT IINSSTSIKG ASQKEVNAQS SDHMPVTQKE QENKSNAFPS 100
    TSCENSFPED CTFLTTENKE ILSLEDKVVD FREKDSSSNL SYQSHDCSGA 150
    CLMKMPLNLK GENPLQLPIK CHFQRRHAKT NSHSSALHVS YKTPCGRSLR 200
    NVEEVFRYLL ETECNFLFTD NFSFNTYVQL ARNYPKQKEV VSDVDISNGV 250
    ESVPISFCNE IDSRKLPQFK YRKTVWPRAY NLTNFSSMFT DSCDCSEGCI 300
    DITKCACLQL TARNAKTSPL SSDKITTGYK YKRLQRQIPT GIYECSLLCK 350
    CNRQLCQNRV VQHGPQVRLQ VFKTEQKGWG VRCLDDIDRG TFVCIYSGRL 400
    LSRANTEKSY GIDENGRDEN TMKNIFSKKR KLEVACSDCE VEVLPLGLET 450
    HPRTAKTEKC PPKFSNNPKE LTMETKYDNI SRIQYHSVIR DPESKTAIFQ 500
    HNGKKMEFVS SESVTPEDND GFKPPREHLN SKTKGAQKDS SSNHVDEFED 550
    NLLIESDVID ITKYREETPP RSRCNQATTL DNQNIKKAIE VQIQKPQEGR 600
    STACQRQQVF CDEELLSETK NTSSDSLTKF NKGNVFLLDA TKEGNVGRFL 650
    NHSCCPNLSV QNVFVETHNR NFPLVAFFTN RYVKARTELT WDYGYEAGTV 700
    PEKEIFCQCG VNKCRKKIL 719
    Length:719
    Mass (Da):81,940
    Last modified:March 21, 2012 - v1
    Checksum:i05DD253EA77F6EC5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACZ03092694 Genomic DNA. No translation available.
    AACZ03092695 Genomic DNA. No translation available.
    GABC01005395 mRNA. Translation: JAA05943.1.
    GABF01000456 mRNA. Translation: JAA21689.1.
    GABD01009723 mRNA. Translation: JAA23377.1.
    GABE01006282 mRNA. Translation: JAA38457.1.
    RefSeqiXP_001153947.1. XM_001153947.3.

    Genome annotation databases

    EnsembliENSPTRT00000048180; ENSPTRP00000042655; ENSPTRG00000005873.
    GeneIDi452719.
    KEGGiptr:452719.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACZ03092694 Genomic DNA. No translation available.
    AACZ03092695 Genomic DNA. No translation available.
    GABC01005395 mRNA. Translation: JAA05943.1 .
    GABF01000456 mRNA. Translation: JAA21689.1 .
    GABD01009723 mRNA. Translation: JAA23377.1 .
    GABE01006282 mRNA. Translation: JAA38457.1 .
    RefSeqi XP_001153947.1. XM_001153947.3.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSPTRT00000048180 ; ENSPTRP00000042655 ; ENSPTRG00000005873 .
    GeneIDi 452719.
    KEGGi ptr:452719.

    Organism-specific databases

    CTDi 83852.

    Phylogenomic databases

    GeneTreei ENSGT00750000117355.
    KOi K11421.
    OMAi KCHFQRR.
    OrthoDBi EOG7ZD1TG.
    TreeFami TF106411.

    Family and domain databases

    Gene3Di 3.30.890.10. 1 hit.
    InterProi IPR016177. DNA-bd_dom.
    IPR001739. Methyl_CpG_DNA-bd.
    IPR007728. Pre-SET_dom.
    IPR001214. SET_dom.
    [Graphical view ]
    Pfami PF01429. MBD. 1 hit.
    PF05033. Pre-SET. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view ]
    SMARTi SM00317. SET. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54171. SSF54171. 1 hit.
    PROSITEi PS50982. MBD. 1 hit.
    PS50867. PRE_SET. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Initial sequence of the chimpanzee genome and comparison with the human genome."
      Chimpanzee sequencing and analysis consortium
      Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
    3. "De novo assembly of the reference chimpanzee transcriptome from NextGen mRNA sequences."
      Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.
      Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Adipose stromalImported, Skeletal muscleImported, SkinImported and Smooth vascularImported.

    Entry informationi

    Entry nameiH2R1P1_PANTR
    AccessioniPrimary (citable) accession number: H2R1P1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 21, 2012
    Last sequence update: March 21, 2012
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3