Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Sulfhydryl oxidase

Gene

QSOX2

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2.UniRule annotation

Cofactori

FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Sulfhydryl oxidaseUniRule annotation (EC:1.8.3.2UniRule annotation)
Gene namesi
Name:QSOX2Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei665 – 682HelicalSequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi476 ↔ 479Redox-activePROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

PaxDbiH2QY61.

Expressioni

Gene expression databases

BgeeiENSPTRG00000021547.

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000036896.

Structurei

3D structure databases

ProteinModelPortaliH2QY61.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 178ThioredoxinInterPro annotationAdd BLAST145
Domaini421 – 530ERV/ALR sulfhydryl oxidaseInterPro annotationAdd BLAST110

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1731. Eukaryota.
ENOG410XVJT. LUCA.
GeneTreeiENSGT00390000008045.
InParanoidiH2QY61.
OMAiLQTMRRY.
OrthoDBiEOG091G038J.
TreeFamiTF316749.

Family and domain databases

Gene3Di1.20.120.310. 1 hit.
InterProiView protein in InterPro
IPR036774. ERV/ALR_sulphydryl_oxid_sf.
IPR017905. ERV/ALR_sulphydryl_oxidase.
IPR036249. Thioredoxin-like_sf.
IPR013766. Thioredoxin_domain.
PfamiView protein in Pfam
PF04777. Evr1_Alr. 1 hit.
PF00085. Thioredoxin. 1 hit.
SUPFAMiSSF52833. SSF52833. 1 hit.
SSF69000. SSF69000. 1 hit.
PROSITEiView protein in PROSITE
PS51324. ERV_ALR. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

H2QY61-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAGAAVAR SPGIGAGPAL RARRSPPPRA ARLPRLLVLL AAAAVGPGAG
60 70 80 90 100
GAARLYRAGE DPVWVLDSGS VRGAPANSSA AWLVQFYWCG CGHCIGYAPT
110 120 130 140 150
WRALAGDVRD WASAIRVAAL DCMEEKNQAV CHDYDIHFYP TFRYFKAFTK
160 170 180 190 200
EFTTGENFKG PDRELRTVRQ TMIDFLQNHT EGSRPPACPR LDPIQPSDVL
210 220 230 240 250
SLLDNRGSHY VAIVFESNSS YLGREVILDL IPYESIVVTR ALDGDKAFLE
260 270 280 290 300
KLGVSSVPSC YLIYPNGSHG LINVVKPLRA FFSSYLKSLP DVRKKSLPLP
310 320 330 340 350
EKPHKEENSE IVVWREFDKS KLYTADLESG LHYLLRVELA AHKSLAGAEL
360 370 380 390 400
KTLKDFVTVL AKLFPGRPPV KKLLEMLQEW LASLPLDRIP YNAVLDLVNN
410 420 430 440 450
KMRISGIFLT NHIKWVGCQG SRSELRGYPC SLWKLFHTLT VEASTHPDAL
460 470 480 490 500
VGTGFEDDPQ AVLQTMRRYI HTFFGCKECG EHFEEMAKES MDSVKTPDQA
510 520 530 540 550
ILWLWKKHNM VNGRLAGHLS EDPRFPKLQW PTPDLCPACH EEIKGLASWD
560 570 580 590 600
EGHVLTLLKQ HYGRDNLLDT YSADQGDSSE GGTLARGEEE EKRLTPPEVS
610 620 630 640 650
HGDRDTQSVR PPGALGPRPA LPESLHHSLD GKLQSLDGPG AHKEVGGAAP
660 670 680 690
FLGVDFSSLD MSLCVVLYVA SSLFLMVMYF FFRVRSRRWK VKHHHPAV
Length:698
Mass (Da):77,489
Last modified:March 21, 2012 - v1
Checksum:iD0AFE8DC5224D196
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03070277 Genomic DNA. No translation available.
AACZ03070278 Genomic DNA. No translation available.
AACZ03070279 Genomic DNA. No translation available.
AACZ03070280 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSPTRT00000039927; ENSPTRP00000036896; ENSPTRG00000021547.

Similar proteinsi

Entry informationi

Entry nameiH2QY61_PANTR
AccessioniPrimary (citable) accession number: H2QY61
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 25, 2017
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported