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Protein
Submitted name:

Neuraminidase 1 (lysosomal sialidase)

Gene

NEU1

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Neuraminidase 1 (lysosomal sialidase)Imported
Submitted name:
Sialidase 1 (Lysosomal sialidase)Imported
Gene namesi
Name:NEU1Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 44HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSPTRG00000017990.

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000030706.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini88 – 377SialidaseInterPro annotationAdd BLAST290

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IE33. Eukaryota.
COG4409. LUCA.
GeneTreeiENSGT00720000108878.
KOiK01186.
OMAiGTEMFAP.
OrthoDBiEOG091G0HAW.
TreeFamiTF331063.

Family and domain databases

InterProiView protein in InterPro
IPR011040. Sialidase.
IPR026856. Sialidase_fam.
IPR036278. Sialidase_sf.
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiView protein in Pfam
PF13088. BNR_2. 1 hit.
SUPFAMiSSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Complete.

H2QSP6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGERPSTAL PDRRWGPRIL GFWGGCRVWV FAAIFLLLSL AASWSKAEND
60 70 80 90 100
FGLVQPLVTM EQLLWVSGRQ IGSVDTFRIP LITATPRGTL LAFAEARKMS
110 120 130 140 150
SSDEGAKFIA LRRSMDQGST WSPTAFIVND GDVPDGLNLG AVVSDVETGV
160 170 180 190 200
VFLFYSLCAH KAGCQVASTM LVWSKDDGVS WSTPRNLSLD IGTEVFAPGP
210 220 230 240 250
GSGIQKQREP RKGRLIVCGH GTLERDGVFC LLSDDHGASW RYGSGVSGIP
260 270 280 290 300
YGQPKQENDF NPDECQPYEL PDGSVVINAR NQNNYHCHCR IVLRSYDACD
310 320 330 340 350
TLRPRDVTFD PELVDPVVAA GAVVTSSGIV FFSNPAHPEF RVNLTLRWSF
360 370 380 390 400
SNGTSWRKET VQLWPGPSGY SSLATLEGSM DGEEQAPQLY VLYEKGRNHY
410
TESISVAKIS VYGTL
Length:415
Mass (Da):45,467
Last modified:March 21, 2012 - v1
Checksum:i360E60A256DEA07F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03049300 Genomic DNA. No translation available.
GABC01006645 mRNA. Translation: JAA04693.1.
GABF01010554 mRNA. Translation: JAA11591.1.
GABD01005088 mRNA. Translation: JAA28012.1.
GABE01011106 mRNA. Translation: JAA33633.1.
RefSeqiXP_001160380.1. XM_001160380.2.

Genome annotation databases

EnsembliENSPTRT00000033233; ENSPTRP00000030706; ENSPTRG00000017990.
GeneIDi471968.
KEGGiptr:471968.

Similar proteinsi

Entry informationi

Entry nameiH2QSP6_PANTR
AccessioniPrimary (citable) accession number: H2QSP6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 25, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported