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Protein
Submitted name:

Sialidase 1 (Lysosomal sialidase)

Gene

NEU1

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase 1 (Lysosomal sialidase)Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:NEU1Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 6

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 44HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSPTRG00000017990.

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000030706.

Structurei

3D structure databases

ProteinModelPortaliH2QSP6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini88 – 377SialidasesInterPro annotationAdd BLAST290

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IE33. Eukaryota.
COG4409. LUCA.
GeneTreeiENSGT00720000108878.
KOiK01186.
OMAiRNQYTES.
OrthoDBiEOG091G0HAW.
TreeFamiTF331063.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR026856. Sialidase_fam.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF13088. BNR_2. 1 hit.
[Graphical view]
SUPFAMiSSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Complete.

H2QSP6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGERPSTAL PDRRWGPRIL GFWGGCRVWV FAAIFLLLSL AASWSKAEND
60 70 80 90 100
FGLVQPLVTM EQLLWVSGRQ IGSVDTFRIP LITATPRGTL LAFAEARKMS
110 120 130 140 150
SSDEGAKFIA LRRSMDQGST WSPTAFIVND GDVPDGLNLG AVVSDVETGV
160 170 180 190 200
VFLFYSLCAH KAGCQVASTM LVWSKDDGVS WSTPRNLSLD IGTEVFAPGP
210 220 230 240 250
GSGIQKQREP RKGRLIVCGH GTLERDGVFC LLSDDHGASW RYGSGVSGIP
260 270 280 290 300
YGQPKQENDF NPDECQPYEL PDGSVVINAR NQNNYHCHCR IVLRSYDACD
310 320 330 340 350
TLRPRDVTFD PELVDPVVAA GAVVTSSGIV FFSNPAHPEF RVNLTLRWSF
360 370 380 390 400
SNGTSWRKET VQLWPGPSGY SSLATLEGSM DGEEQAPQLY VLYEKGRNHY
410
TESISVAKIS VYGTL
Length:415
Mass (Da):45,467
Last modified:March 21, 2012 - v1
Checksum:i360E60A256DEA07F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03049300 Genomic DNA. No translation available.
GABC01006645 mRNA. Translation: JAA04693.1.
GABF01010554 mRNA. Translation: JAA11591.1.
GABD01005088 mRNA. Translation: JAA28012.1.
GABE01011106 mRNA. Translation: JAA33633.1.
RefSeqiXP_001160380.1. XM_001160380.2.

Genome annotation databases

EnsembliENSPTRT00000033233; ENSPTRP00000030706; ENSPTRG00000017990.
GeneIDi471968.
KEGGiptr:471968.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03049300 Genomic DNA. No translation available.
GABC01006645 mRNA. Translation: JAA04693.1.
GABF01010554 mRNA. Translation: JAA11591.1.
GABD01005088 mRNA. Translation: JAA28012.1.
GABE01011106 mRNA. Translation: JAA33633.1.
RefSeqiXP_001160380.1. XM_001160380.2.

3D structure databases

ProteinModelPortaliH2QSP6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000030706.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000033233; ENSPTRP00000030706; ENSPTRG00000017990.
GeneIDi471968.
KEGGiptr:471968.

Organism-specific databases

CTDi4758.

Phylogenomic databases

eggNOGiENOG410IE33. Eukaryota.
COG4409. LUCA.
GeneTreeiENSGT00720000108878.
KOiK01186.
OMAiRNQYTES.
OrthoDBiEOG091G0HAW.
TreeFamiTF331063.

Gene expression databases

BgeeiENSPTRG00000017990.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR026856. Sialidase_fam.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF13088. BNR_2. 1 hit.
[Graphical view]
SUPFAMiSSF50939. SSF50939. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiH2QSP6_PANTR
AccessioniPrimary (citable) accession number: H2QSP6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: November 2, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.