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H2QSP6

- H2QSP6_PANTR

UniProt

H2QSP6 - H2QSP6_PANTR

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Protein
Submitted name:

Sialidase 1 (Lysosomal sialidase)

Gene

NEU1

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: Ensembl

GO - Biological processi

  1. oligosaccharide catabolic process Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase 1 (Lysosomal sialidase)Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:NEU1Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
ProteomesiUP000002277: Chromosome 6

Subcellular locationi

GO - Cellular componenti

  1. cell junction Source: Ensembl
  2. extracellular vesicular exosome Source: Ensembl
  3. lysosome Source: Ensembl
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliH2QSP6.
SMRiH2QSP6. Positions 55-396.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00720000108878.
InParanoidiH2QSP6.
KOiK01186.
OMAiGTEMFAP.
OrthoDBiEOG779NXT.
TreeFamiTF331063.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR026856. Sialidase_fam.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
SUPFAMiSSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Complete.

H2QSP6-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MTGERPSTAL PDRRWGPRIL GFWGGCRVWV FAAIFLLLSL AASWSKAEND
60 70 80 90 100
FGLVQPLVTM EQLLWVSGRQ IGSVDTFRIP LITATPRGTL LAFAEARKMS
110 120 130 140 150
SSDEGAKFIA LRRSMDQGST WSPTAFIVND GDVPDGLNLG AVVSDVETGV
160 170 180 190 200
VFLFYSLCAH KAGCQVASTM LVWSKDDGVS WSTPRNLSLD IGTEVFAPGP
210 220 230 240 250
GSGIQKQREP RKGRLIVCGH GTLERDGVFC LLSDDHGASW RYGSGVSGIP
260 270 280 290 300
YGQPKQENDF NPDECQPYEL PDGSVVINAR NQNNYHCHCR IVLRSYDACD
310 320 330 340 350
TLRPRDVTFD PELVDPVVAA GAVVTSSGIV FFSNPAHPEF RVNLTLRWSF
360 370 380 390 400
SNGTSWRKET VQLWPGPSGY SSLATLEGSM DGEEQAPQLY VLYEKGRNHY
410
TESISVAKIS VYGTL
Length:415
Mass (Da):45,467
Last modified:March 21, 2012 - v1
Checksum:i360E60A256DEA07F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACZ03049300 Genomic DNA. No translation available.
GABC01006645 mRNA. Translation: JAA04693.1.
GABF01010554 mRNA. Translation: JAA11591.1.
GABD01005088 mRNA. Translation: JAA28012.1.
GABE01011106 mRNA. Translation: JAA33633.1.
RefSeqiXP_001160380.1. XM_001160380.1.

Genome annotation databases

EnsembliENSPTRT00000033233; ENSPTRP00000030706; ENSPTRG00000017990.
GeneIDi471968.
KEGGiptr:471968.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACZ03049300 Genomic DNA. No translation available.
GABC01006645 mRNA. Translation: JAA04693.1 .
GABF01010554 mRNA. Translation: JAA11591.1 .
GABD01005088 mRNA. Translation: JAA28012.1 .
GABE01011106 mRNA. Translation: JAA33633.1 .
RefSeqi XP_001160380.1. XM_001160380.1.

3D structure databases

ProteinModelPortali H2QSP6.
SMRi H2QSP6. Positions 55-396.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSPTRT00000033233 ; ENSPTRP00000030706 ; ENSPTRG00000017990 .
GeneIDi 471968.
KEGGi ptr:471968.

Organism-specific databases

CTDi 4758.

Phylogenomic databases

GeneTreei ENSGT00720000108878.
InParanoidi H2QSP6.
KOi K01186.
OMAi GTEMFAP.
OrthoDBi EOG779NXT.
TreeFami TF331063.

Family and domain databases

Gene3Di 2.120.10.10. 1 hit.
InterProi IPR026856. Sialidase_fam.
IPR011040. Sialidases.
[Graphical view ]
PANTHERi PTHR10628. PTHR10628. 1 hit.
SUPFAMi SSF50939. SSF50939. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Initial sequence of the chimpanzee genome and comparison with the human genome."
    Chimpanzee sequencing and analysis consortium
    Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  3. "De novo assembly of the reference chimpanzee transcriptome from NextGen mRNA sequences."
    Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.
    Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Adipose stromalImported, Skeletal muscleImported, SkinImported and Smooth vascularImported.

Entry informationi

Entry nameiH2QSP6_PANTR
AccessioniPrimary (citable) accession number: H2QSP6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 29, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3