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H2QS92

- H2QS92_PANTR

UniProt

H2QS92 - H2QS92_PANTR

Protein
Submitted name:

Coagulation factor XIII, A1 polypeptide

Gene

F13A1

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (21 Mar 2012)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 calcium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei315 – 3151UniRule annotation
    Active sitei374 – 3741UniRule annotation
    Active sitei397 – 3971UniRule annotation
    Metal bindingi437 – 4371Calcium
    Metal bindingi439 – 4391Calcium
    Metal bindingi486 – 4861Calcium
    Metal bindingi491 – 4911Calcium

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

    GO - Biological processi

    1. blood coagulation Source: Ensembl
    2. peptide cross-linking Source: Ensembl

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Coagulation factor XIII, A1 polypeptideImported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:F13A1Imported
    OrganismiPan troglodytes (Chimpanzee)Imported
    Taxonomic identifieri9598 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
    ProteomesiUP000002277: Chromosome 6

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00740000115156.
    KOiK03917.
    OMAiCEEDAVY.
    OrthoDBiEOG7WT40M.
    TreeFamiTF324278.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view]
    PANTHERiPTHR11590. PTHR11590. 1 hit.
    PfamiPF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
    SMARTiSM00460. TGc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H2QS92-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSETSRTAFG GRRAVPPNNS NAAEDDLPTV ELQGVVPRGV NLQEFLNVTS    50
    VHLFKERWDT NKVDHHTDKY ENNKLIVRRG QSFYVQIDFN RPYDPRRDLF 100
    RVEYVIGRYP QENKGTYIPV PIVSELQSGK WGAKIVMRED RSVRLSIQSS 150
    PKCIVGKFRM YVAVWTPYGV LRTSRNPETD TYILFNPWCE DDAVYLDNEK 200
    EREEYVLNDI GVIFYGEVND IKTRSWSYGQ FEDGILDTCL YVMDRAQMDL 250
    SGRGNPIKVS RVGSAMVNAK DDEGVLVGSW DNIYAYGVPP SAWTGSVDIL 300
    LEYRSSENPV RYGQCWVFAG VFNTFLRCLG IPARIVTNYF SAHDNDANLQ 350
    MDIFLEEDGN VNSKLTKDSV WNYHCWNEAW MTRPDLPVGF GGWQAVDSTP 400
    QENSDGMYRC GPASVQAIKH GHVCFQFDAP FVFAEVNSDL IYITAKKDGT 450
    HVVENVDATH IGKLIVTKQI GGDGMMDITD TYKFQEGQEE ERLALETALM 500
    YGAKKPLNTE GVVKSRSNVD MDFEVENAVL GKDFKLSITF RNNSHNRYTI 550
    TAYLSANITF YTGVPKAEFK KETFDVTLEP LSFKKEAVLI QAGEYMGQLL 600
    EQASLHFFVT ARINETRDVL AKQKSTVLTI PEIIIKVRGT QVVGSDMTVT 650
    VEFTNPLKET LRNVWIHLDG PGITRPMKKM FREIRPNSTV QWEEVCRPWV 700
    SGHRKLIASM SSDSLRHVYG ELDVQIQRRP SM 732
    Length:732
    Mass (Da):83,291
    Last modified:March 21, 2012 - v1
    Checksum:iB2CBF4AFF850A54A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACZ03047284 Genomic DNA. No translation available.
    AACZ03047285 Genomic DNA. No translation available.
    AACZ03047286 Genomic DNA. No translation available.
    AACZ03047287 Genomic DNA. No translation available.
    AACZ03047288 Genomic DNA. No translation available.
    AACZ03047289 Genomic DNA. No translation available.
    AACZ03047290 Genomic DNA. No translation available.
    AACZ03047291 Genomic DNA. No translation available.
    AACZ03047292 Genomic DNA. No translation available.
    GABE01004747 mRNA. Translation: JAA39992.1.
    RefSeqiXP_518220.3. XM_518220.3.

    Genome annotation databases

    EnsembliENSPTRT00000032699; ENSPTRP00000030210; ENSPTRG00000017694.
    GeneIDi462413.
    KEGGiptr:462413.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACZ03047284 Genomic DNA. No translation available.
    AACZ03047285 Genomic DNA. No translation available.
    AACZ03047286 Genomic DNA. No translation available.
    AACZ03047287 Genomic DNA. No translation available.
    AACZ03047288 Genomic DNA. No translation available.
    AACZ03047289 Genomic DNA. No translation available.
    AACZ03047290 Genomic DNA. No translation available.
    AACZ03047291 Genomic DNA. No translation available.
    AACZ03047292 Genomic DNA. No translation available.
    GABE01004747 mRNA. Translation: JAA39992.1 .
    RefSeqi XP_518220.3. XM_518220.3.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSPTRT00000032699 ; ENSPTRP00000030210 ; ENSPTRG00000017694 .
    GeneIDi 462413.
    KEGGi ptr:462413.

    Organism-specific databases

    CTDi 2162.

    Phylogenomic databases

    GeneTreei ENSGT00740000115156.
    KOi K03917.
    OMAi CEEDAVY.
    OrthoDBi EOG7WT40M.
    TreeFami TF324278.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view ]
    PANTHERi PTHR11590. PTHR11590. 1 hit.
    Pfami PF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
    SMARTi SM00460. TGc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Initial sequence of the chimpanzee genome and comparison with the human genome."
      Chimpanzee sequencing and analysis consortium
      Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
    3. "De novo assembly of the reference chimpanzee transcriptome from NextGen mRNA sequences."
      Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.
      Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Skeletal muscleImported.

    Entry informationi

    Entry nameiH2QS92_PANTR
    AccessioniPrimary (citable) accession number: H2QS92
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 21, 2012
    Last sequence update: March 21, 2012
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3