H2QS92 (H2QS92_PANTR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Coagulation factor XIII, A1 polypeptide EMBL JAA39992.1

Submitted name:
Uncharacterized protein Ensembl ENSPTRP00000030210

Gene names

Name:	ENSG00000124491 Ensembl ENSPTRP00000030210
Synonyms:	F13A1 EMBL JAA39992.1

Organism

Pan troglodytes (Chimpanzee) [Reference proteome] Ensembl ENSPTRP00000030210

Taxonomic identifier

9598 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Pan

Protein attributes

Sequence length	732 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Cofactor

Binds 1 calcium ion per subunit By similarity. PIRSR PIRSR000459-2

Ontologies

Keywords
Ligand	Calcium PIRSR PIRSR000459-2 Metal-binding PIRSR PIRSR000459-2
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	peptide cross-linking Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	315	1	By similarity PIRSR PIRSR000459-1
	Active site	374	1	By similarity PIRSR PIRSR000459-1
	Active site	397	1	By similarity PIRSR PIRSR000459-1
	Metal binding	437	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	439	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	486	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	491	1	Calcium By similarity PIRSR PIRSR000459-2

Sequences

	Sequence		Length	Mass (Da)
	H2QS92 [UniParc]. Last modified March 21, 2012. Version 1. Checksum: B2CBF4AFF850A54A	FASTA	732	83,291
	10 20 30 40 50 60 MSETSRTAFG GRRAVPPNNS NAAEDDLPTV ELQGVVPRGV NLQEFLNVTS VHLFKERWDT 70 80 90 100 110 120 NKVDHHTDKY ENNKLIVRRG QSFYVQIDFN RPYDPRRDLF RVEYVIGRYP QENKGTYIPV 130 140 150 160 170 180 PIVSELQSGK WGAKIVMRED RSVRLSIQSS PKCIVGKFRM YVAVWTPYGV LRTSRNPETD 190 200 210 220 230 240 TYILFNPWCE DDAVYLDNEK EREEYVLNDI GVIFYGEVND IKTRSWSYGQ FEDGILDTCL 250 260 270 280 290 300 YVMDRAQMDL SGRGNPIKVS RVGSAMVNAK DDEGVLVGSW DNIYAYGVPP SAWTGSVDIL 310 320 330 340 350 360 LEYRSSENPV RYGQCWVFAG VFNTFLRCLG IPARIVTNYF SAHDNDANLQ MDIFLEEDGN 370 380 390 400 410 420 VNSKLTKDSV WNYHCWNEAW MTRPDLPVGF GGWQAVDSTP QENSDGMYRC GPASVQAIKH 430 440 450 460 470 480 GHVCFQFDAP FVFAEVNSDL IYITAKKDGT HVVENVDATH IGKLIVTKQI GGDGMMDITD 490 500 510 520 530 540 TYKFQEGQEE ERLALETALM YGAKKPLNTE GVVKSRSNVD MDFEVENAVL GKDFKLSITF 550 560 570 580 590 600 RNNSHNRYTI TAYLSANITF YTGVPKAEFK KETFDVTLEP LSFKKEAVLI QAGEYMGQLL 610 620 630 640 650 660 EQASLHFFVT ARINETRDVL AKQKSTVLTI PEIIIKVRGT QVVGSDMTVT VEFTNPLKET 670 680 690 700 710 720 LRNVWIHLDG PGITRPMKKM FREIRPNSTV QWEEVCRPWV SGHRKLIASM SSDSLRHVYG 730 ELDVQIQRRP SM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Initial sequence of the chimpanzee genome and comparison with the human genome." Chimpanzee sequencing and analysis consortium Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.
[3]	"De novo assembly of the reference chimpanzee transcriptome from NextGen mRNA sequences." Maudhoo M.D., Meehan D.T., Norgren R.B.Jr. Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Skeletal muscle EMBL JAA39992.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AACZ03047284 Genomic DNA. No translation available. AACZ03047285 Genomic DNA. No translation available. AACZ03047286 Genomic DNA. No translation available. AACZ03047287 Genomic DNA. No translation available. AACZ03047288 Genomic DNA. No translation available. AACZ03047289 Genomic DNA. No translation available. AACZ03047290 Genomic DNA. No translation available. AACZ03047291 Genomic DNA. No translation available. AACZ03047292 Genomic DNA. No translation available. GABE01004747 mRNA. Translation: JAA39992.1.
RefSeq	XP_518220.3. XM_518220.3.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSPTRT00000032699; ENSPTRP00000030210; ENSPTRG00000017694.
GeneID	462413.
KEGG	ptr:462413.
Organism-specific databases
CTD	2162.
Phylogenomic databases
GeneTree	ENSGT00690000101887.
KO	K03917.
OMA	GTHVVEA.
Family and domain databases
Gene3D	2.60.40.10. 3 hits. 3.90.260.10. 1 hit.
InterPro	IPR023608. Gln_gamma-glutamylTfrase_euk. IPR013783. Ig-like_fold. IPR014756. Ig_E-set. IPR002931. Transglutaminase-like. IPR008958. Transglutaminase_C. IPR013808. Transglutaminase_CS. IPR001102. Transglutaminase_N. [Graphical view]
PANTHER	PTHR11590. PTHR11590. 1 hit.
Pfam	PF00927. Transglut_C. 2 hits. PF01841. Transglut_core. 1 hit. PF00868. Transglut_N. 1 hit. [Graphical view]
PIRSF	PIRSF000459. TGM_EBP42. 1 hit.
SMART	SM00460. TGc. 1 hit. [Graphical view]
SUPFAM	SSF81296. Ig_E-set. 1 hit. SSF49309. Transglut_C. 2 hits.
PROSITE	PS00547. TRANSGLUTAMINASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

H2QS92_PANTR

Accession

Primary (citable) accession number: H2QS92

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2012
Last sequence update:	March 21, 2012
Last modified:	May 29, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)