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H2QS92

- H2QS92_PANTR

UniProt

H2QS92 - H2QS92_PANTR

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Protein
Submitted name:

Coagulation factor XIII, A1 polypeptide

Gene
F13A1
Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

Cofactori

Binds 1 calcium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei315 – 3151 By similarityUniRule annotation
Active sitei374 – 3741 By similarityUniRule annotation
Active sitei397 – 3971 By similarityUniRule annotation
Metal bindingi437 – 4371Calcium By similarityUniRule annotation
Metal bindingi439 – 4391Calcium By similarityUniRule annotation
Metal bindingi486 – 4861Calcium By similarityUniRule annotation
Metal bindingi491 – 4911Calcium By similarityUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

GO - Biological processi

  1. blood coagulation Source: Ensembl
  2. peptide cross-linking Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Coagulation factor XIII, A1 polypeptideImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:F13A1Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
ProteomesiUP000002277: Chromosome 6

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00740000115156.
KOiK03917.
OMAiCEEDAVY.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H2QS92-1 [UniParc]FASTAAdd to Basket

« Hide

MSETSRTAFG GRRAVPPNNS NAAEDDLPTV ELQGVVPRGV NLQEFLNVTS    50
VHLFKERWDT NKVDHHTDKY ENNKLIVRRG QSFYVQIDFN RPYDPRRDLF 100
RVEYVIGRYP QENKGTYIPV PIVSELQSGK WGAKIVMRED RSVRLSIQSS 150
PKCIVGKFRM YVAVWTPYGV LRTSRNPETD TYILFNPWCE DDAVYLDNEK 200
EREEYVLNDI GVIFYGEVND IKTRSWSYGQ FEDGILDTCL YVMDRAQMDL 250
SGRGNPIKVS RVGSAMVNAK DDEGVLVGSW DNIYAYGVPP SAWTGSVDIL 300
LEYRSSENPV RYGQCWVFAG VFNTFLRCLG IPARIVTNYF SAHDNDANLQ 350
MDIFLEEDGN VNSKLTKDSV WNYHCWNEAW MTRPDLPVGF GGWQAVDSTP 400
QENSDGMYRC GPASVQAIKH GHVCFQFDAP FVFAEVNSDL IYITAKKDGT 450
HVVENVDATH IGKLIVTKQI GGDGMMDITD TYKFQEGQEE ERLALETALM 500
YGAKKPLNTE GVVKSRSNVD MDFEVENAVL GKDFKLSITF RNNSHNRYTI 550
TAYLSANITF YTGVPKAEFK KETFDVTLEP LSFKKEAVLI QAGEYMGQLL 600
EQASLHFFVT ARINETRDVL AKQKSTVLTI PEIIIKVRGT QVVGSDMTVT 650
VEFTNPLKET LRNVWIHLDG PGITRPMKKM FREIRPNSTV QWEEVCRPWV 700
SGHRKLIASM SSDSLRHVYG ELDVQIQRRP SM 732
Length:732
Mass (Da):83,291
Last modified:March 21, 2012 - v1
Checksum:iB2CBF4AFF850A54A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACZ03047284 Genomic DNA. No translation available.
AACZ03047285 Genomic DNA. No translation available.
AACZ03047286 Genomic DNA. No translation available.
AACZ03047287 Genomic DNA. No translation available.
AACZ03047288 Genomic DNA. No translation available.
AACZ03047289 Genomic DNA. No translation available.
AACZ03047290 Genomic DNA. No translation available.
AACZ03047291 Genomic DNA. No translation available.
AACZ03047292 Genomic DNA. No translation available.
GABE01004747 mRNA. Translation: JAA39992.1.
RefSeqiXP_518220.3. XM_518220.3.

Genome annotation databases

EnsembliENSPTRT00000032699; ENSPTRP00000030210; ENSPTRG00000017694.
GeneIDi462413.
KEGGiptr:462413.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACZ03047284 Genomic DNA. No translation available.
AACZ03047285 Genomic DNA. No translation available.
AACZ03047286 Genomic DNA. No translation available.
AACZ03047287 Genomic DNA. No translation available.
AACZ03047288 Genomic DNA. No translation available.
AACZ03047289 Genomic DNA. No translation available.
AACZ03047290 Genomic DNA. No translation available.
AACZ03047291 Genomic DNA. No translation available.
AACZ03047292 Genomic DNA. No translation available.
GABE01004747 mRNA. Translation: JAA39992.1 .
RefSeqi XP_518220.3. XM_518220.3.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSPTRT00000032699 ; ENSPTRP00000030210 ; ENSPTRG00000017694 .
GeneIDi 462413.
KEGGi ptr:462413.

Organism-specific databases

CTDi 2162.

Phylogenomic databases

GeneTreei ENSGT00740000115156.
KOi K03917.
OMAi CEEDAVY.
OrthoDBi EOG7WT40M.
TreeFami TF324278.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Initial sequence of the chimpanzee genome and comparison with the human genome."
    Chimpanzee sequencing and analysis consortium
    Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  3. "De novo assembly of the reference chimpanzee transcriptome from NextGen mRNA sequences."
    Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.
    Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Skeletal muscleImported.

Entry informationi

Entry nameiH2QS92_PANTR
AccessioniPrimary (citable) accession number: H2QS92
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: September 3, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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