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Protein
Submitted name:

Coagulation factor XIII, A1 polypeptide

Gene

F13A1

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei315 – 3151UniRule annotation
Active sitei374 – 3741UniRule annotation
Active sitei397 – 3971UniRule annotation

GO - Molecular functioni

  1. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

GO - Biological processi

  1. blood coagulation Source: Ensembl
  2. peptide cross-linking Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Coagulation factor XIII, A1 polypeptideImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:F13A1Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
ProteomesiUP000002277 Componenti: Chromosome 6

Subcellular locationi

GO - Cellular componenti

  1. blood microparticle Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119108.
InParanoidiH2QS92.
KOiK03917.
OMAiCEEDAVY.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H2QS92-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSETSRTAFG GRRAVPPNNS NAAEDDLPTV ELQGVVPRGV NLQEFLNVTS
60 70 80 90 100
VHLFKERWDT NKVDHHTDKY ENNKLIVRRG QSFYVQIDFN RPYDPRRDLF
110 120 130 140 150
RVEYVIGRYP QENKGTYIPV PIVSELQSGK WGAKIVMRED RSVRLSIQSS
160 170 180 190 200
PKCIVGKFRM YVAVWTPYGV LRTSRNPETD TYILFNPWCE DDAVYLDNEK
210 220 230 240 250
EREEYVLNDI GVIFYGEVND IKTRSWSYGQ FEDGILDTCL YVMDRAQMDL
260 270 280 290 300
SGRGNPIKVS RVGSAMVNAK DDEGVLVGSW DNIYAYGVPP SAWTGSVDIL
310 320 330 340 350
LEYRSSENPV RYGQCWVFAG VFNTFLRCLG IPARIVTNYF SAHDNDANLQ
360 370 380 390 400
MDIFLEEDGN VNSKLTKDSV WNYHCWNEAW MTRPDLPVGF GGWQAVDSTP
410 420 430 440 450
QENSDGMYRC GPASVQAIKH GHVCFQFDAP FVFAEVNSDL IYITAKKDGT
460 470 480 490 500
HVVENVDATH IGKLIVTKQI GGDGMMDITD TYKFQEGQEE ERLALETALM
510 520 530 540 550
YGAKKPLNTE GVVKSRSNVD MDFEVENAVL GKDFKLSITF RNNSHNRYTI
560 570 580 590 600
TAYLSANITF YTGVPKAEFK KETFDVTLEP LSFKKEAVLI QAGEYMGQLL
610 620 630 640 650
EQASLHFFVT ARINETRDVL AKQKSTVLTI PEIIIKVRGT QVVGSDMTVT
660 670 680 690 700
VEFTNPLKET LRNVWIHLDG PGITRPMKKM FREIRPNSTV QWEEVCRPWV
710 720 730
SGHRKLIASM SSDSLRHVYG ELDVQIQRRP SM
Length:732
Mass (Da):83,291
Last modified:March 21, 2012 - v1
Checksum:iB2CBF4AFF850A54A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03047284 Genomic DNA. No translation available.
AACZ03047285 Genomic DNA. No translation available.
AACZ03047286 Genomic DNA. No translation available.
AACZ03047287 Genomic DNA. No translation available.
AACZ03047288 Genomic DNA. No translation available.
AACZ03047289 Genomic DNA. No translation available.
AACZ03047290 Genomic DNA. No translation available.
AACZ03047291 Genomic DNA. No translation available.
AACZ03047292 Genomic DNA. No translation available.
GABE01004747 mRNA. Translation: JAA39992.1.
RefSeqiXP_009448724.1. XM_009450449.1.
XP_518220.3. XM_518220.4.

Genome annotation databases

EnsembliENSPTRT00000032699; ENSPTRP00000030210; ENSPTRG00000017694.
GeneIDi462413.
KEGGiptr:462413.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03047284 Genomic DNA. No translation available.
AACZ03047285 Genomic DNA. No translation available.
AACZ03047286 Genomic DNA. No translation available.
AACZ03047287 Genomic DNA. No translation available.
AACZ03047288 Genomic DNA. No translation available.
AACZ03047289 Genomic DNA. No translation available.
AACZ03047290 Genomic DNA. No translation available.
AACZ03047291 Genomic DNA. No translation available.
AACZ03047292 Genomic DNA. No translation available.
GABE01004747 mRNA. Translation: JAA39992.1.
RefSeqiXP_009448724.1. XM_009450449.1.
XP_518220.3. XM_518220.4.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000032699; ENSPTRP00000030210; ENSPTRG00000017694.
GeneIDi462413.
KEGGiptr:462413.

Organism-specific databases

CTDi2162.

Phylogenomic databases

GeneTreeiENSGT00760000119108.
InParanoidiH2QS92.
KOiK03917.
OMAiCEEDAVY.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Initial sequence of the chimpanzee genome and comparison with the human genome."
    Chimpanzee sequencing and analysis consortium
    Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  3. "De novo assembly of the reference chimpanzee transcriptome from NextGen mRNA sequences."
    Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.
    Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Skeletal muscleImported.

Entry informationi

Entry nameiH2QS92_PANTR
AccessioniPrimary (citable) accession number: H2QS92
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: April 1, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.