H2QQG8 (H2QQG8_PANTR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Nei endonuclease VIII-like 3 EMBL JAA07560.1

Submitted name:
Uncharacterized protein Ensembl ENSPTRP00000028509

Gene names

Name:	ENSG00000109674 Ensembl ENSPTRP00000028509
Synonyms:	NEIL3 EMBL JAA07560.1

Organism

Pan troglodytes (Chimpanzee) [Reference proteome] Ensembl ENSPTRP00000028509

Taxonomic identifier

9598 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Pan

Protein attributes

Sequence length	606 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Endonuclease EMBL JAA07560.1 Hydrolase Nuclease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	base-excision repair Inferred from electronic annotation. Source: InterPro nucleotide-excision repair Inferred from electronic annotation. Source: InterPro
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA-(apurinic or apyrimidinic site) lyase activity Inferred from electronic annotation. Source: InterPro damaged DNA binding Inferred from electronic annotation. Source: InterPro endonuclease activity Inferred from electronic annotation. Source: UniProtKB-KW hydrolase activity, hydrolyzing N-glycosyl compounds Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	H2QQG8 [UniParc]. Last modified March 21, 2012. Version 1. Checksum: 0E84967C9EE00955	FASTA	606	68,025
	10 20 30 40 50 60 MVEGPGCTLN GEKIRARVLP GQAVTSVRGS ALRSLQGRAL RLAASTAVVS PQAAALNNND 70 80 90 100 110 120 SSQNVLSLFN GYVYSGVETL GKELFMYFGP KALRIHFGMK GFIMINPLEY KYKNGASPVL 130 140 150 160 170 180 EVQLTKDLIC FFDSSVELRN SMESQQRIRM MKELDVCSSE FSFLRAESEV KKQKGRMLGD 190 200 210 220 230 240 VLMDQNVLPG VGNIIKNEAL FDSGLHPAVK VCQLTDEQIH HLMKMIRDFS ILFYRCRKAG 250 260 270 280 290 300 LALSKHYKVY KRPNCGQCHC RITVCRFGDN NRMTYFCPHC QKENPQHVDI CKLPTRNTII 310 320 330 340 350 360 SWTSSRVDHV MDSVARKSEE HWTCVVCTLI NKPSSKACDA CLTSRPIDSV LKSEENSTVF 370 380 390 400 410 420 SHLMKYPCNT FGKPHTEVKI NRKTAFGTTT LVLTDFSNKS STLERKTKQN QILDEEFQNS 430 440 450 460 470 480 TPTNVCLNDI QHPSKKTTND ITQLSSKVNI SPTISSESKL FSPAHKKLKT AHYSSAELKS 490 500 510 520 530 540 CNPGYSNSEL QINITDGPHT LNPDSPRCSK HNRLCILRVV RKDGENKGRQ FYACPLPREA 550 560 570 580 590 600 QCGFFEWADL SFPFCNHGKR SIMKTVLKIG PNNGKNFFVC PLGKEKQCNF FQWAENGPGI KIIPGC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Initial sequence of the chimpanzee genome and comparison with the human genome." Chimpanzee sequencing and analysis consortium Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.
[3]	"De novo assembly of the reference chimpanzee transcriptome from NextGen mRNA sequences." Maudhoo M.D., Meehan D.T., Norgren R.B.Jr. Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Adipose stromal EMBL JAA07560.1 and Skeletal muscle EMBL JAA42838.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AACZ03031124 Genomic DNA. No translation available. AACZ03031125 Genomic DNA. No translation available. AACZ03031126 Genomic DNA. No translation available. GABC01003778 mRNA. Translation: JAA07560.1. GABE01001901 mRNA. Translation: JAA42838.1.
RefSeq	XP_526741.2. XM_526741.3.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSPTRT00000030869; ENSPTRP00000028509; ENSPTRG00000016617.
GeneID	471359.
KEGG	ptr:471359.
Organism-specific databases
CTD	55247.
Phylogenomic databases
GeneTree	ENSGT00510000048146.
KO	K10569.
OMA	TKDLICF.
Family and domain databases
InterPro	IPR015886. DNA_glyclase/AP_lyase_DNA-bd. IPR015887. DNA_glyclase_Znf_dom_DNA_BS. IPR012319. DNA_glycosylase/AP_lyase_cat. IPR010979. Ribosomal_S13-like_H2TH. IPR000214. Znf_DNA_glyclase/AP_lyase. IPR010666. Znf_GRF. IPR001876. Znf_RanBP2. [Graphical view]
Pfam	PF06831. H2TH. 1 hit. PF06839. zf-GRF. 2 hits. PF00641. zf-RanBP. 1 hit. [Graphical view]
SMART	SM00547. ZnF_RBZ. 1 hit. [Graphical view]
SUPFAM	SSF81624. Form_DNAglyc_cat. 1 hit. SSF46946. Ribosomal_H2TH. 1 hit.
PROSITE	PS51068. FPG_CAT. 1 hit. PS01242. ZF_FPG_1. 1 hit. PS51066. ZF_FPG_2. 1 hit. PS01358. ZF_RANBP2_1. 1 hit. PS50199. ZF_RANBP2_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

H2QQG8_PANTR

Accession

Primary (citable) accession number: H2QQG8

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2012
Last sequence update:	March 21, 2012
Last modified:	March 6, 2013
This is version 7 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)