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Protein
Submitted name:

Hydroxyacyl-CoA dehydrogenase

Gene

HADH

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei73Coenzyme AUniRule annotation1
Binding sitei80Coenzyme AUniRule annotation1
Binding sitei149Coenzyme AUniRule annotation1
Sitei170Important for catalytic activityUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Hydroxyacyl-CoA dehydrogenaseImported
Gene namesi
Name:HADHImported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiH2QQ04.

Expressioni

Gene expression databases

BgeeiENSPTRG00000016351.

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000028089.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 2143HCDH_NInterPro annotationAdd BLAST186
Domaini253 – 3303HCDHInterPro annotationAdd BLAST78

Phylogenomic databases

eggNOGiKOG2304. Eukaryota.
COG1250. LUCA.
GeneTreeiENSGT00880000137923.
InParanoidiH2QQ04.
OMAiMAHPMGP.
OrthoDBiEOG091G089P.
TreeFamiTF300886.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
InterProiView protein in InterPro
IPR022694. 3-OHacyl-CoA_DH.
IPR006176. 3-OHacyl-CoA_DH_NAD-bd.
IPR006108. 3HC_DH_C.
IPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR036291. NAD(P)-bd_dom_sf.
PfamiView protein in Pfam
PF00725. 3HCDH. 1 hit.
PF02737. 3HCDH_N. 1 hit.
PIRSFiPIRSF000105. HCDH. 2 hits.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

H2QQ04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFVTRQLMR SVSSSSTASA SAKKIIVKHV TVIGGGLMGA GIAQVAAATG
60 70 80 90 100
HTVVLVDQTE DILAKSKKGI EESLRKVAKK KFAENPKAGD EFVEKTLSTI
110 120 130 140 150
VTSTDAASVV HSTDLVVEAI VENLKVKNEL FKRLDKFAAE HTIFASNTSS
160 170 180 190 200
LQITSIANAT TRQDRFAGLH FFNPVPVMKL VEVIKTPMTS QKTFESLVDF
210 220 230 240 250
SKALGKHPVS CKDTPGFIVN RLLVPYLMEA IRLYERDFQT CGDSNSGLGF
260 270 280 290 300
SLKGDASKED IDTAMKLGAG YPMGPFELLD YVGLDTTKFI VDGWHEMDAE
310 320 330
NPLHQPSPSL NKLVAENKFG KKTGEGFYKY K
Length:331
Mass (Da):36,029
Last modified:March 21, 2012 - v1
Checksum:i75192160FDCF146D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03035168 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSPTRT00000030423; ENSPTRP00000028089; ENSPTRG00000016351.

Similar proteinsi

Entry informationi

Entry nameiH2QQ04_PANTR
AccessioniPrimary (citable) accession number: H2QQ04
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 25, 2017
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported