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H2QPA4 (H2QPA4_PANTR) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Superoxide dismutase [Cu-Zn] RuleBase RU000393
EC=1.15.1.1 RuleBase RU000393
Gene names
Name:ENSG00000109610 Ensembl ENSPTRP00000027474
Synonyms:SOD3 EMBL JAA07374.1
OrganismPan troglodytes (Chimpanzee) [Reference proteome] Ensembl ENSPTRP00000027474
Taxonomic identifier9598 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Pan

Protein attributes

Sequence length240 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity. RuleBase RU000393

Catalytic activity

2 superoxide + 2 H+ = O2 + H2O2. RuleBase RU000393

Cofactor

Binds 1 copper ion per subunit By similarity. RuleBase RU000393

Binds 1 zinc ion per subunit By similarity. RuleBase RU000393

Sequence similarities

Belongs to the Cu-Zn superoxide dismutase family. RuleBase RU000393

Sequences

Sequence LengthMass (Da)Tools
H2QPA4 [UniParc].

Last modified March 21, 2012. Version 1.
Checksum: 585B8DEBFC506CF4

FASTA24025,851
        10         20         30         40         50         60 
MLALLCSCLL LAAGASDAWT GEDSAEPNSD SAEWIRDMYA KVTEIWQEVM QRRDDDGALH 

        70         80         90        100        110        120 
AACQVQPSAT LDAAQPRVTG VVLFRQLAPR AKLDAFFALE GFPTEPNSSS RAIHVHQFGD 

       130        140        150        160        170        180 
LSQGCESTGP HYNPLAVPHP QHPGDFGNFA VRDGSLWRYR AGLAASLAGP HSIVGRAVVV 

       190        200        210        220        230        240 
HAGEDDLGRG GNQASVENGN AGRRLACCVV GVCGPGLWER QAREHSERKK RRRESECKAA

« Hide

References

« Hide 'large scale' references
[1]"Initial sequence of the chimpanzee genome and comparison with the human genome."
Chimpanzee sequencing and analysis consortium
Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
[3]"De novo assembly of the reference chimpanzee transcriptome from NextGen mRNA sequences."
Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.
Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Adipose stromal EMBL JAA07374.1, Skeletal muscle EMBL JAA36341.1, Skin EMBL JAA32942.1 and Smooth vascular EMBL JAA16261.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AACZ03031637 Genomic DNA. No translation available.
GABC01003964 mRNA. Translation: JAA07374.1.
GABF01005884 mRNA. Translation: JAA16261.1.
GABD01000158 mRNA. Translation: JAA32942.1.
GABE01008398 mRNA. Translation: JAA36341.1.
GABE01008397 mRNA. Translation: JAA36342.1.
RefSeqXP_001164716.1. XM_001164716.3.

3D structure databases

ModBaseSearch...

Proteomic databases

PRIDEH2QPA4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSPTRT00000029775; ENSPTRP00000027474; ENSPTRG00000015956.
GeneID461143.
KEGGptr:461143.

Organism-specific databases

CTD6649.

Phylogenomic databases

GeneTreeENSGT00530000063226.
KOK16627.
OMACCVIGIC.

Family and domain databases

Gene3D2.60.40.200. 1 hit.
InterProIPR024134. SOD_Cu/Zn_/chaperones.
IPR018152. SOD_Cu/Zn_BS.
IPR024141. SOD_Cu/Zn_extracel.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PANTHERPTHR10003. PTHR10003. 1 hit.
PTHR10003:SF10. PTHR10003:SF10. 1 hit.
PfamPF00080. Sod_Cu. 1 hit.
[Graphical view]
PRINTSPR00068. CUZNDISMTASE.
SUPFAMSSF49329. SOD_Cu_Zn. 1 hit.
PROSITEPS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH2QPA4_PANTR
AccessionPrimary (citable) accession number: H2QPA4
Entry history
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: May 1, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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