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Protein
Submitted name:

WAP four-disulfide core domain 2

Gene

WFDC2

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
WAP four-disulfide core domain 2Imported
Submitted name:
WFDC2 isoform 4Imported
Gene namesi
Name:WFDC2Imported
ORF Names:CK820_G0020002Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 20

Organism-specific databases

VGNCiVGNC:10138 WFDC2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_501457592831 – 124Sequence analysisAdd BLAST94

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi49 ↔ 61PROSITE-ProRule annotation
Disulfide bondi97 ↔ 109PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

PaxDbiH2QKF8

Expressioni

Gene expression databases

BgeeiENSPTRG00000013549

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000023271

Structurei

3D structure databases

ProteinModelPortaliH2QKF8
SMRiH2QKF8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 66WAPInterPro annotationAdd BLAST38
Domaini73 – 123WAPInterPro annotationAdd BLAST51

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J36N Eukaryota
ENOG41125F3 LUCA
GeneTreeiENSGT00730000111410
InParanoidiH2QKF8
OMAiDLNCTQE
OrthoDBiEOG091G0UW4

Family and domain databases

Gene3Di4.10.75.10, 2 hits
InterProiView protein in InterPro
IPR036645 Elafin-like_sf
IPR008197 WAP_dom
PfamiView protein in Pfam
PF00095 WAP, 2 hits
PRINTSiPR00003 4DISULPHCORE
SMARTiView protein in SMART
SM00217 WAP, 2 hits
SUPFAMiSSF57256 SSF57256, 2 hits
PROSITEiView protein in PROSITE
PS51390 WAP, 2 hits

Sequencei

Sequence statusi: Complete.

H2QKF8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPACRLGPLA AALLLSLLLF GFTLVSGTGA EKTGVCPELQ ADQNCTQECV
60 70 80 90 100
SDSECADNLK CCSAGCATFC SLPNDKEGSC PQVNINFPQL GLCRDQCQVD
110 120
SQCPGQMKCC RNGCGKVSCV TPNF
Length:124
Mass (Da):12,993
Last modified:March 21, 2012 - v1
Checksum:i9536B00B385259AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04052828 Genomic DNA No translation available.
NBAG03000253 Genomic DNA Translation: PNI59853.1
RefSeqiXP_009435581.1, XM_009437306.2

Genome annotation databases

EnsembliENSPTRT00000025216; ENSPTRP00000023271; ENSPTRG00000013549
GeneIDi458283
KEGGiptr:458283

Similar proteinsi

Entry informationi

Entry nameiH2QKF8_PANTR
AccessioniPrimary (citable) accession number: H2QKF8
Secondary accession number(s): A0A2J8MK01
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: May 23, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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