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H2QJU2

- H2QJU2_PANTR

UniProt

H2QJU2 - H2QJU2_PANTR

Protein
Submitted name:

Uncharacterized protein

Gene

TGM6

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (21 Mar 2012)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 calcium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei274 – 2741UniRule annotation
    Active sitei333 – 3331UniRule annotation
    Active sitei356 – 3561UniRule annotation
    Metal bindingi396 – 3961CalciumUniRule annotation
    Metal bindingi398 – 3981CalciumUniRule annotation
    Metal bindingi445 – 4451CalciumUniRule annotation
    Metal bindingi450 – 4501CalciumUniRule annotation

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

    GO - Biological processi

    1. peptide cross-linking Source: InterPro

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:TGM6Imported
    OrganismiPan troglodytes (Chimpanzee)Imported
    Taxonomic identifieri9598 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
    ProteomesiUP000002277: Chromosome 20

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00740000115034.
    OMAiWRGSVAI.
    OrthoDBiEOG7WT40M.
    TreeFamiTF324278.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view]
    PANTHERiPTHR11590. PTHR11590. 1 hit.
    PfamiPF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
    SMARTiSM00460. TGc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H2QJU2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAGIRVTKVD WQRSRNGAAH HTQEYPCPEL VVRRGQSFSL TLELSRALDC    50
    EETLIFTVET GPRASEALHT KAVFQTSELE RGEGWTAARE AQMENTLTVS 100
    LASPPSAVIG RYLLSIRLSS HRKHSNRRLG EFVLLFNPWC AEDDVFLASE 150
    EERQEYVLND SGIIFRGVEK HIRAQGWNYG QFQEDILDIC LSILDRSPGH 200
    QNNPATDVSC RHNPIYVTRV ISAMVNSNND RGVVQGQWQG KYGGGTSPLH 250
    WRGSVAILQK WLKGRYKPVK YGQCWVFAGV MCTVLRCLGI ATRVVSNFNS 300
    AHDTDQNLSV DKYVDSFGRT LEDLTEDSMW NLHVWNESWF ARQDIGPSYN 350
    GWQVMDATPQ EESEGVFRCG PASVTAIREG DVHLAHDGPF VFAEVNADYI 400
    TWLWHEDESR ERVYSNTKKI GRCISTKAVG SDSRVDITDL YKYPEGSRKE 450
    RQVYSKAVNR LFGVEASGRR TWIRRAGGRC LWRDDLLEPA TKPSIAGKFK 500
    VLEPPMLGHD LRLALCLANL TSRAQRVRVN LSGATILYTR KPVAEILHES 550
    HAVRLGPQEE KRIPITISYS KYKEDLTEDK KILLAAMCLV TKGEKLLVEK 600
    DITLEDFITI KVLGPAMVGV AVTVEVTVVN PLIERVKDCA LMAEGSGLLQ 650
    EQLSIDVPTL EPQERASVQF DITPSKSGPR QLQVDLVSPH FPDIKGFVIV 700
    HVATAK 706
    Length:706
    Mass (Da):79,243
    Last modified:March 21, 2012 - v1
    Checksum:i77C0537E3C2BCDD7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACZ03122178 Genomic DNA. No translation available.
    AACZ03122179 Genomic DNA. No translation available.
    AACZ03122180 Genomic DNA. No translation available.
    AACZ03122181 Genomic DNA. No translation available.
    AACZ03122182 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSPTRT00000024450; ENSPTRP00000022554; ENSPTRG00000013175.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACZ03122178 Genomic DNA. No translation available.
    AACZ03122179 Genomic DNA. No translation available.
    AACZ03122180 Genomic DNA. No translation available.
    AACZ03122181 Genomic DNA. No translation available.
    AACZ03122182 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSPTRT00000024450 ; ENSPTRP00000022554 ; ENSPTRG00000013175 .

    Phylogenomic databases

    GeneTreei ENSGT00740000115034.
    OMAi WRGSVAI.
    OrthoDBi EOG7WT40M.
    TreeFami TF324278.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view ]
    PANTHERi PTHR11590. PTHR11590. 1 hit.
    Pfami PF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
    SMARTi SM00460. TGc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Initial sequence of the chimpanzee genome and comparison with the human genome."
      Chimpanzee sequencing and analysis consortium
      Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiH2QJU2_PANTR
    AccessioniPrimary (citable) accession number: H2QJU2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 21, 2012
    Last sequence update: March 21, 2012
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3