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H2QJU1

- H2QJU1_PANTR

UniProt

H2QJU1 - H2QJU1_PANTR

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Protein
Submitted name:

Uncharacterized protein

Gene

TGM3

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cofactori

Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei273 – 2731UniRule annotation
Active sitei331 – 3311UniRule annotation
Active sitei354 – 3541UniRule annotation
Metal bindingi394 – 3941CalciumUniRule annotation
Metal bindingi396 – 3961CalciumUniRule annotation
Metal bindingi444 – 4441CalciumUniRule annotation
Metal bindingi449 – 4491CalciumUniRule annotation

GO - Molecular functioni

  1. calcium ion binding Source: Ensembl
  2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

GO - Biological processi

  1. cell envelope organization Source: Ensembl
  2. keratinocyte differentiation Source: Ensembl
  3. peptide cross-linking Source: Ensembl
  4. protein tetramerization Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TGM3Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
ProteomesiUP000002277: Chromosome 20

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. extracellular vesicular exosome Source: Ensembl
  3. extrinsic component of cytoplasmic side of plasma membrane Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119108.
InParanoidiH2QJU1.
KOiK05620.
OMAiEILPTRS.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H2QJU1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAALGVQSIN WQTAFNRQAH HTDRFSSQEL ILRRGQNFQV LMIMNKGLGS
60 70 80 90 100
NERLEFIVST GPYPSESAMT KAVFPLSNGS SGGWSAVLQA SNGNTLTISI
110 120 130 140 150
SSPASAPIGR YTMALQIFSQ GGISSVKLGT FILLFNPWLN VDSVFMGNHA
160 170 180 190 200
EREEYVQEDA GIIFVGSTNR IGMIGWNFGQ FEEDILSICL SILDRSLNFR
210 220 230 240 250
RDAAADVARR NDPKYVGRVL SAMINSNDDN GVLAGNWSGT YTGGRDPRNW
260 270 280 290 300
NGSVEILKTW KKSGFSPVRY GQCWVFAGTL NTALRSLGIP SRVITNFNSA
310 320 330 340 350
HDTDRNLSVD VYYDPMGNPL DKGSDSVWNF HVWNEGWFVR SDLGPSYGGW
360 370 380 390 400
QVLDATPQER SQGVFQCGPA SVIGVREGDV QLNFDMPFIF AEVNADRITW
410 420 430 440 450
LYNNTTGKQW KNSVNSHTIG RYISTKAVGS NARMDVTDKY KYPEGSDQER
460 470 480 490 500
QVFQKALGKL KPNASFGATS SMGLETEEQE PSIIGKLKVA GMLAVGKEVS
510 520 530 540 550
LVLLLKNLSR DTKTVTVNMT AWTIIYNGTL VHEVWKDSAT MSLDPEEEAE
560 570 580 590 600
HPIKISYAQY EKYLKSDNMI RITAVCKVPD ESEVVVERDV ILDNPTLTLE
610 620 630 640 650
VLNEARVRKP VNVQMLFSNP LDEPVRDCVL MVEGSGLLLG NLKIDVPTLG
660 670 680 690
PKERSRVRFD ILPTRSGTKQ LLADFSCNKF PAIKAMLSID VAE
Length:693
Mass (Da):76,730
Last modified:March 21, 2012 - v1
Checksum:i3C787B2CB7D93611
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACZ03122182 Genomic DNA. No translation available.
AACZ03122183 Genomic DNA. No translation available.
RefSeqiXP_514468.2. XM_514468.3.

Genome annotation databases

EnsembliENSPTRT00000024449; ENSPTRP00000022553; ENSPTRG00000013174.
GeneIDi458043.
KEGGiptr:458043.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACZ03122182 Genomic DNA. No translation available.
AACZ03122183 Genomic DNA. No translation available.
RefSeqi XP_514468.2. XM_514468.3.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSPTRT00000024449 ; ENSPTRP00000022553 ; ENSPTRG00000013174 .
GeneIDi 458043.
KEGGi ptr:458043.

Organism-specific databases

CTDi 7053.

Phylogenomic databases

GeneTreei ENSGT00760000119108.
InParanoidi H2QJU1.
KOi K05620.
OMAi EILPTRS.
OrthoDBi EOG7WT40M.
TreeFami TF324278.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Initial sequence of the chimpanzee genome and comparison with the human genome."
    Chimpanzee sequencing and analysis consortium
    Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiH2QJU1_PANTR
AccessioniPrimary (citable) accession number: H2QJU1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 29, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3