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H2QI73

- H2QI73_PANTR

UniProt

H2QI73 - H2QI73_PANTR

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Protein
Submitted name: Hexokinase 2
Gene
HK2
Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: Ensembl

GO - Biological processi

  1. apoptotic mitochondrial changes Source: Ensembl
  2. glucose metabolic process Source: Ensembl
  3. glycolytic process Source: UniProtKB-KW
  4. regulation of glucose import Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase 2Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:HK2Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
ProteomesiUP000002277: Mitochondrion, UP000002277: Unplaced

Subcellular locationi

GO - Cellular componenti

  1. mitochondrial outer membrane Source: Ensembl
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000017159.
KOiK00844.
OMAiHHLGLES.
OrthoDBiEOG7S21X5.
TreeFamiTF314238.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H2QI73-1 [UniParc]FASTAAdd to Basket

« Hide

MIASHLLAYF FTELNHDQVQ KVDQYLYHMR LSDETLLEIS KRFRKEMEKG    50
LGATTHPTAA VKMLPTFVRS TPDGTEHGEF LALDLGGTNF RVLWVKVTDN 100
GLQKVEMENQ IYAIPEDIMR GSGTQLFDHI AECLANFMDK LQIKDKKLPL 150
GFTFSFPCHQ TKLDESFLVS WTKGFKSSGV EGRDVVALIR KAIQRRGDFD 200
IDIVAVVNDT VGTMMTCGYD DHNCEIGLIV GTGSNACYME EMRHIDMVEG 250
DEGRMCINME WGAFGDDGSL NDIRTEFDQE IDMGSLNPGK QLFEKMISGM 300
YMGELVRLIL VKMAKEELLF GGKLSPELLN TGRFETKDIS DIEGEKDGIR 350
KAREVLMRLG LDPTQEDCVA THRICQIVST RSASLCAATL AAVLQRIKEN 400
KGEERLRSTI GVDGSVYKKH PHFAKRLHKT VRRLVPGCDV RFLRSEDGSG 450
KGAAMVTAVA YRLADQHRAR QKTLEHLQLS HDQLLEVKRR MKVEMERGLS 500
KETHASAPVK MLPTYVCATP DGTEKGDFLA LDLGGTNFRV LLVRVRNGKW 550
GGVEMHNKIY AVPQEVMHGT GDELFDHIVQ CIADFLEYMG MKGVSLPLGF 600
TFSFPCQQNS LDESILLKWT KGFKASGCEG EDVVTLLKEA IHRREEFDLD 650
VVAVVNDTVG TMMTCGFEDP HCEVGLIVGT GSNACYMEEM RNVELVEGEE 700
GRMCVNMEWG AFGDNGCLDD FRTEFDVAVD ELSLNPGKQR FEKMISGMYL 750
GEIVRNILID FTKRGLLFRG RISERLKTRG IFETKFLSQI ESDCLALLQV 800
RAILQHLGLE STCDDSIIVK EVCTVVARRA AQLCGAGMAA VVDKIRENRG 850
LDALKVTVGV DGTLYKLHPH FAKVMHETVK DLAPKCDVSF LQSEDGSGKG 900
AALITAVACR IREAGQR 917
Length:917
Mass (Da):102,338
Last modified:March 21, 2012 - v1
Checksum:i16A1A37A18CB840C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACZ03013144 Genomic DNA. No translation available.
AACZ03013145 Genomic DNA. No translation available.
AACZ03013146 Genomic DNA. No translation available.
AACZ03013147 Genomic DNA. No translation available.
GABF01001991 mRNA. Translation: JAA20154.1.
GABD01000403 mRNA. Translation: JAA32697.1.
RefSeqiXP_001162535.1. XM_001162535.3.

Genome annotation databases

EnsembliENSPTRT00000022509; ENSPTRP00000020771; ENSPTRG00000012104.
GeneIDi741291.
KEGGiptr:741291.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACZ03013144 Genomic DNA. No translation available.
AACZ03013145 Genomic DNA. No translation available.
AACZ03013146 Genomic DNA. No translation available.
AACZ03013147 Genomic DNA. No translation available.
GABF01001991 mRNA. Translation: JAA20154.1 .
GABD01000403 mRNA. Translation: JAA32697.1 .
RefSeqi XP_001162535.1. XM_001162535.3.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSPTRT00000022509 ; ENSPTRP00000020771 ; ENSPTRG00000012104 .
GeneIDi 741291.
KEGGi ptr:741291.

Organism-specific databases

CTDi 3099.

Phylogenomic databases

GeneTreei ENSGT00390000017159.
KOi K00844.
OMAi HHLGLES.
OrthoDBi EOG7S21X5.
TreeFami TF314238.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
PROSITEi PS00378. HEXOKINASES. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of the chimpanzee Y chromosome."
    Hughes J.F., Pyntikova T., Skaletsky H., Minx P.J., Rozen S., Wilson R.K., Page D.C.
    Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Initial sequence of the chimpanzee genome and comparison with the human genome."
    Chimpanzee sequencing and analysis consortium
    Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  4. "De novo assembly of the reference chimpanzee transcriptome from NextGen mRNA sequences."
    Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.
    Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: SkinImported and Smooth vascularImported.

Entry informationi

Entry nameiH2QI73_PANTR
AccessioniPrimary (citable) accession number: H2QI73
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: June 11, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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