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Protein
Submitted name:

Hexokinase 2

Gene

HK2

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotationImported, Transferase
Biological processGlycolysisSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase 2Imported
Gene namesi
Name:HK2Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 2A

Organism-specific databases

VGNCiVGNC:265 HK2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSPTRG00000012104

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000020771

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 219Hexokinase_1InterPro annotationAdd BLAST198
Domaini225 – 459Hexokinase_2InterPro annotationAdd BLAST235
Domaini471 – 667Hexokinase_1InterPro annotationAdd BLAST197
Domaini673 – 907Hexokinase_2InterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the hexokinase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1369 Eukaryota
COG5026 LUCA
GeneTreeiENSGT00390000017159
KOiK00844
OMAiHAIAPVK
OrthoDBiEOG091G08MD
TreeFamiTF314238

Family and domain databases

InterProiView protein in InterPro
IPR001312 Hexokinase
IPR019807 Hexokinase_BS
IPR022673 Hexokinase_C
IPR022672 Hexokinase_N
PANTHERiPTHR19443 PTHR19443, 4 hits
PfamiView protein in Pfam
PF00349 Hexokinase_1, 2 hits
PF03727 Hexokinase_2, 2 hits
PROSITEiView protein in PROSITE
PS00378 HEXOKINASE_1, 2 hits
PS51748 HEXOKINASE_2, 2 hits

Sequencei

Sequence statusi: Complete.

H2QI73-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIASHLLAYF FTELNHDQVQ KVDQYLYHMR LSDETLLEIS KRFRKEMEKG
60 70 80 90 100
LGATTHPTAA VKMLPTFVRS TPDGTEHGEF LALDLGGTNF RVLWVKVTDN
110 120 130 140 150
GLQKVEMENQ IYAIPEDIMR GSGTQLFDHI AECLANFMDK LQIKDKKLPL
160 170 180 190 200
GFTFSFPCHQ TKLDESFLVS WTKGFKSSGV EGRDVVALIR KAIQRRGDFD
210 220 230 240 250
IDIVAVVNDT VGTMMTCGYD DHNCEIGLIV GTGSNACYME EMRHIDMVEG
260 270 280 290 300
DEGRMCINME WGAFGDDGSL NDIRTEFDQE IDMGSLNPGK QLFEKMISGM
310 320 330 340 350
YMGELVRLIL VKMAKEELLF AGKLSPELLN TGRFETKDIS DIEGEKDGIR
360 370 380 390 400
KAREVLMRLG LDPTQEDCVA THRICQIVST RSASLCAATL AAVLQRIKEN
410 420 430 440 450
KGEERLRSTI GVDGSVYKKH PHFAKRLHKT VRRLVPGCDV RFLRSEDGSG
460 470 480 490 500
KGAAMVTAVA YRLADQHRAR QKTLEHLQLS HDQLLEVKRR MKVEMERGLS
510 520 530 540 550
KETHASAPVK MLPTYVCATP DGTEKGDFLA LDLGGTNFRV LLVRVRNGKW
560 570 580 590 600
GGVEMHNKIY AVPQEVMHGT GDELFDHIVQ CIADFLEYMG MKGVSLPLGF
610 620 630 640 650
TFSFPCQQNS LDESILLKWT KGFKASGCEG EDVVTLLKEA IHRREEFDLD
660 670 680 690 700
VVAVVNDTVG TMMTCGFEDP HCEVGLIVGT GSNACYMEEM RNVELVEGEE
710 720 730 740 750
GRMCVNMEWG AFGDNGCLDD FRTEFDVAVD ELSLNPGKQR FEKMISGMYL
760 770 780 790 800
GEIVRNILID FTKRGLLFRG RISERLKTRG IFETKFLSQI ESDCLALLQV
810 820 830 840 850
RAILQHLGLE STCDDSIIVK EVCTVVARRA AQLCGAGMAA VVDKIRENRG
860 870 880 890 900
LDALKVTVGV DGTLYKLHPH FAKVMHETVK DLAPKCDVSF LQSEDGSGKG
910
AALITAVACR IREAGQR
Length:917
Mass (Da):102,352
Last modified:February 28, 2018 - v2
Checksum:i846F8E933F004D19
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04063591 Genomic DNA No translation available.
GABC01003500 mRNA Translation: JAA07838.1
RefSeqiXP_001162535.2, XM_001162535.5

Genome annotation databases

EnsembliENSPTRT00000022509; ENSPTRP00000020771; ENSPTRG00000012104
GeneIDi741291
KEGGiptr:741291

Similar proteinsi

Entry informationi

Entry nameiH2QI73_PANTR
AccessioniPrimary (citable) accession number: H2QI73
Secondary accession number(s): K7AIR3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: February 28, 2018
Last modified: April 25, 2018
This is version 45 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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