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Protein

Guanine nucleotide-binding protein subunit gamma

Gene

GNG2

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransducerUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Guanine nucleotide-binding protein subunit gammaUniRule annotation
Gene namesi
Name:GNG2Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

PTM / Processingi

Keywords - PTMi

LipoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiENSPTRG00000006342.

Interactioni

Subunit structurei

G proteins are composed of 3 units; alpha, beta and gamma.UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000010751.

Structurei

3D structure databases

SMRiH2Q8A8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 71G protein gammaInterPro annotationAdd BLAST67

Sequence similaritiesi

Belongs to the G protein gamma family.UniRule annotation

Phylogenomic databases

eggNOGiKOG4119. Eukaryota.
ENOG41122JF. LUCA.
GeneTreeiENSGT00760000119218.
KOiK07826.
OMAiETSEMAS.
OrthoDBiEOG091G17J0.
TreeFamiTF319909.

Family and domain databases

CDDicd00068. GGL. 1 hit.
InterProiView protein in InterPro
IPR015898. G-protein_gamma-like_dom.
IPR036284. GGL_sf.
IPR001770. Gprotein-gamma.
PANTHERiPTHR13809. PTHR13809. 1 hit.
PfamiView protein in Pfam
PF00631. G-gamma. 1 hit.
PRINTSiPR00321. GPROTEING.
SMARTiView protein in SMART
SM00224. GGL. 1 hit.
SUPFAMiSSF48670. SSF48670. 1 hit.
PROSITEiView protein in PROSITE
PS50058. G_PROTEIN_GAMMA. 1 hit.

Sequencei

Sequence statusi: Complete.

H2Q8A8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASNNTASIA QARKLVEQLK MEANIDRIKV SKAAADLMAY CEAHAKEDPL
60 70
LTPVPASENP FREKKFFCAI L
Length:71
Mass (Da):7,850
Last modified:March 21, 2012 - v1
Checksum:iEDB74E4135E7A37A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03094717 Genomic DNA. No translation available.
GABC01002803 mRNA. Translation: JAA08535.1.
GABF01006290 mRNA. Translation: JAA15855.1.
GABD01009772 mRNA. Translation: JAA23328.1.
GABE01006034 mRNA. Translation: JAA38705.1.
RefSeqiXP_001158320.1. XM_001158320.4.
XP_001158380.1. XM_001158380.3.
XP_016781570.1. XM_016926081.1.
XP_016781571.1. XM_016926082.1.
XP_016781572.1. XM_016926083.1.
XP_016781573.1. XM_016926084.1.

Genome annotation databases

EnsembliENSPTRT00000011613; ENSPTRP00000010751; ENSPTRG00000006342.
GeneIDi467457.
KEGGiptr:467457.

Similar proteinsi

Entry informationi

Entry nameiH2Q8A8_PANTR
AccessioniPrimary (citable) accession number: H2Q8A8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 25, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported