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H2Q5W6

- H2Q5W6_PANTR

UniProt

H2Q5W6 - H2Q5W6_PANTR

Protein
Submitted name:

Uncharacterized protein

Gene

GPD1

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 15 (01 Oct 2014)
      Sequence version 1 (21 Mar 2012)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei120 – 1201SubstrateUniRule annotation
    Active sitei204 – 2041Proton acceptorUniRule annotation

    GO - Molecular functioni

    1. glycerol-3-phosphate dehydrogenase [NAD+] activity Source: InterPro
    2. glycerol-3-phosphate dehydrogenase activity Source: Ensembl
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. cellular response to cAMP Source: Ensembl
    2. cellular response to tumor necrosis factor Source: Ensembl
    3. gluconeogenesis Source: Ensembl
    4. glycerol-3-phosphate catabolic process Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Ligandi

    NADUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:GPD1Imported
    OrganismiPan troglodytes (Chimpanzee)Imported
    Taxonomic identifieri9598 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
    ProteomesiUP000002277: Chromosome 12

    Subcellular locationi

    GO - Cellular componenti

    1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
    2. mitochondrion Source: Ensembl

    Structurei

    3D structure databases

    ProteinModelPortaliH2Q5W6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni269 – 2702Substrate binding

    Sequence similaritiesi

    Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00390000003114.
    KOiK00006.
    OMAiPVGEFIH.
    OrthoDBiEOG7ZKSBS.
    TreeFamiTF300836.

    Family and domain databases

    Gene3Di1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    InterProiIPR008927. 6-PGluconate_DH_C-like.
    IPR013328. DH_multihelical.
    IPR006168. G3P_DH_NAD-dep.
    IPR006109. G3P_DH_NAD-dep_C.
    IPR017751. G3P_DH_NAD-dep_euk.
    IPR011128. G3P_DH_NAD-dep_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PANTHERiPTHR11728. PTHR11728. 1 hit.
    PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
    PF01210. NAD_Gly3P_dh_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
    PRINTSiPR00077. GPDHDRGNASE.
    SUPFAMiSSF48179. SSF48179. 1 hit.
    TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
    PROSITEiPS00957. NAD_G3PDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H2Q5W6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASKKVCIVG SGNWGSAIAK IVGGNAAQLA QFDPRVTMWV FEEDIGGKKL    50
    TEIINTQHEN VKYLPGHKLP PNVVAVPDVV QAAEDADILI FVVPHQFIGK 100
    ICDQLKGHLK ANATGISLIK GVDEGPNGLK LISEVIGERL GIPMSVLMGA 150
    NIASEVADEK FCETTIGCKD PAQGQLLKEL MQTPNFRITV VQEVDTVEIC 200
    GALKNVVAVG AGFCDGLGFG DNTKAAVIRL GLMEMIAFAK LFCSGPVSSA 250
    TFLESCGVAD LITTCYGGRN RKVAEAFART GKSIEQLEKE LLNGQKLQGP 300
    ETARELHSIL QHKGLVDKFP LFMAVYKVCY EGQPVGEFIH CLQNHPEHM 349
    Length:349
    Mass (Da):37,542
    Last modified:March 21, 2012 - v1
    Checksum:iCE7B62C4047576EF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACZ03088368 Genomic DNA. No translation available.
    RefSeqiXP_001154939.1. XM_001154939.2.

    Genome annotation databases

    EnsembliENSPTRT00000009103; ENSPTRP00000008412; ENSPTRG00000004925.
    GeneIDi741054.
    KEGGiptr:741054.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACZ03088368 Genomic DNA. No translation available.
    RefSeqi XP_001154939.1. XM_001154939.2.

    3D structure databases

    ProteinModelPortali H2Q5W6.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSPTRT00000009103 ; ENSPTRP00000008412 ; ENSPTRG00000004925 .
    GeneIDi 741054.
    KEGGi ptr:741054.

    Organism-specific databases

    CTDi 2819.

    Phylogenomic databases

    GeneTreei ENSGT00390000003114.
    KOi K00006.
    OMAi PVGEFIH.
    OrthoDBi EOG7ZKSBS.
    TreeFami TF300836.

    Family and domain databases

    Gene3Di 1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    InterProi IPR008927. 6-PGluconate_DH_C-like.
    IPR013328. DH_multihelical.
    IPR006168. G3P_DH_NAD-dep.
    IPR006109. G3P_DH_NAD-dep_C.
    IPR017751. G3P_DH_NAD-dep_euk.
    IPR011128. G3P_DH_NAD-dep_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    PANTHERi PTHR11728. PTHR11728. 1 hit.
    Pfami PF07479. NAD_Gly3P_dh_C. 1 hit.
    PF01210. NAD_Gly3P_dh_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000114. Glycerol-3-P_dh. 1 hit.
    PRINTSi PR00077. GPDHDRGNASE.
    SUPFAMi SSF48179. SSF48179. 1 hit.
    TIGRFAMsi TIGR03376. glycerol3P_DH. 1 hit.
    PROSITEi PS00957. NAD_G3PDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Initial sequence of the chimpanzee genome and comparison with the human genome."
      Chimpanzee sequencing and analysis consortium
      Nature 437:69-87(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiH2Q5W6_PANTR
    AccessioniPrimary (citable) accession number: H2Q5W6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 21, 2012
    Last sequence update: March 21, 2012
    Last modified: October 1, 2014
    This is version 15 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3