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Protein

Coatomer subunit delta

Gene

ARCN1

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.UniRule annotation

GO - Biological processi

Keywordsi

Biological processER-Golgi transportUniRule annotation, Protein transportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Coatomer subunit deltaUniRule annotation
Gene namesi
Name:ARCN1Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation, Cytoplasmic vesicleUniRule annotation, Golgi apparatusUniRule annotation, MembraneUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiH2Q4W6.

Expressioni

Gene expression databases

BgeeiENSPTRG00000004350.

Interactioni

Subunit structurei

Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.UniRule annotation

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000007459.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini271 – 511MHDInterPro annotationAdd BLAST241

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili147 – 179Sequence analysisAdd BLAST33

Sequence similaritiesi

Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2635. Eukaryota.
ENOG410XRH2. LUCA.
GeneTreeiENSGT00390000017207.
OMAiKTFVEMD.
OrthoDBiEOG091G08B5.
TreeFamiTF105760.

Family and domain databases

InterProiView protein in InterPro
IPR036168. AP2_Mu_C_sf.
IPR022775. AP_mu_sigma_su.
IPR027059. Coatomer_dsu.
IPR011012. Longin-like_dom_sf.
IPR028565. MHD.
PANTHERiPTHR10121. PTHR10121. 1 hit.
PfamiView protein in Pfam
PF00928. Adap_comp_sub. 1 hit.
PF01217. Clat_adaptor_s. 1 hit.
SUPFAMiSSF49447. SSF49447. 1 hit.
SSF64356. SSF64356. 1 hit.
PROSITEiView protein in PROSITE
PS51072. MHD. 1 hit.

Sequencei

Sequence statusi: Complete.

H2Q4W6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLLAAAVCT KAGKAIVSRQ FVEMTRTRIE GLLAAFPKLM NTGKQHTFVE
60 70 80 90 100
TESVRYVYQP MEKLYMVLIT TKNSNILEDL ETLRLFSRVI PEYCRALEEN
110 120 130 140 150
EISEHCFDLI FAFDEIVALG YRENVNLAQI RTFTEMDSHE EKVFRAVRET
160 170 180 190 200
QEREAKAEMR RKAKELQQAR RDAERQGKKA PGFGGFGSSA VSGGSTAAMI
210 220 230 240 250
TETIIETDKP KVAPAPARPS GPSKALKLGA KGKEVDNFVD KLKSEGETIM
260 270 280 290 300
SSSMGKRTSE ATKMHAPPIN MESVHMKIEE KITLTCGRDG GLQNMELHGM
310 320 330 340 350
IMLRISDDKY GRIRLHVENE DKKGVQLQTH PNVDKKLFTA ESLIGLKNPE
360 370 380 390 400
KSFPVNSDVG VLKWRLQTTE ESFIPLTINC WPSESGNGCD VNIEYELQED
410 420 430 440 450
NLELNDVVIT IPLPSGVGAP VIGEIDGEYR HDSRRNTLEW CLPVIDAKNK
460 470 480 490 500
SGSLEFSIAG QPNDFFPVQV SFVSKKNYCN IQVTKVTQVD GNSPVRFSTE
510
TTFLVDKYEI L
Length:511
Mass (Da):57,210
Last modified:March 21, 2012 - v1
Checksum:i4ED1F7D2D12A7F75
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03080838 Genomic DNA. No translation available.
AACZ03080839 Genomic DNA. No translation available.
AACZ03080840 Genomic DNA. No translation available.
GABC01000036 mRNA. Translation: JAA11302.1.
GABF01000886 mRNA. Translation: JAA21259.1.
GABF01000885 mRNA. Translation: JAA21260.1.
GABF01000884 mRNA. Translation: JAA21261.1.
GABF01000883 mRNA. Translation: JAA21262.1.
GABF01000882 mRNA. Translation: JAA21263.1.
GABF01000881 mRNA. Translation: JAA21264.1.
GABF01000880 mRNA. Translation: JAA21265.1.
GABD01003175 mRNA. Translation: JAA29925.1.
GABE01000211 mRNA. Translation: JAA44528.1.
RefSeqiXP_508795.2. XM_508795.5.

Genome annotation databases

EnsembliENSPTRT00000008080; ENSPTRP00000007459; ENSPTRG00000004350.
GeneIDi451590.

Similar proteinsi

Entry informationi

Entry nameiH2Q4W6_PANTR
AccessioniPrimary (citable) accession number: H2Q4W6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: January 31, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported