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Protein
Submitted name:

Uncharacterized protein

Gene

KCNQ4

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Potassium channelSAAS annotation
Biological processIon transport, Potassium transport, Transport
LigandPotassium

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:KCNQ4Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei99 – 121HelicalSequence analysisAdd BLAST23
Transmembranei133 – 153HelicalSequence analysisAdd BLAST21
Transmembranei174 – 199HelicalSequence analysisAdd BLAST26
Transmembranei239 – 258HelicalSequence analysisAdd BLAST20
Transmembranei299 – 324HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiH2PYS7.

Expressioni

Gene expression databases

BgeeiENSPTRG00000000597.

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000001033.

Structurei

3D structure databases

ProteinModelPortaliH2PYS7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini100 – 324Ion_transInterPro annotationAdd BLAST225
Domaini464 – 646KCNQ_channelInterPro annotationAdd BLAST183

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1419. Eukaryota.
COG1226. LUCA.
GeneTreeiENSGT00550000074513.
InParanoidiH2PYS7.
OMAiWAFVYHV.
OrthoDBiEOG091G02ZT.
TreeFamiTF315186.

Family and domain databases

InterProiView protein in InterPro
IPR005821. Ion_trans_dom.
IPR003937. K_chnl_volt-dep_KCNQ.
IPR013821. K_chnl_volt-dep_KCNQ_C.
IPR015573. KCQN4.
IPR028325. VG_K_chnl.
PANTHERiPTHR11537. PTHR11537. 1 hit.
PTHR11537:SF4. PTHR11537:SF4. 1 hit.
PfamiView protein in Pfam
PF00520. Ion_trans. 1 hit.
PF03520. KCNQ_channel. 1 hit.
PRINTSiPR00169. KCHANNEL.
PR01459. KCNQCHANNEL.

Sequencei

Sequence statusi: Complete.

H2PYS7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEAPPRRLG LGPPPGDAPR AELVALTAVQ SEQGEAGGGG SPRRLGLLGS
60 70 80 90 100
PLPPGAPLPG PGSGSGSACG QRSSAAHKRY RRLQNWVYNV LERPRGWAFV
110 120 130 140 150
YHVFIFLLVF SCLVLSVLST IQEHQELANE CLLILEFVMI VVFGLEYIVR
160 170 180 190 200
VWSAGCCCRY RGWQGRFRFA RKPFCVIDFI VFVASVAVIA AGTQGNIFAT
210 220 230 240 250
SALRSMRFLQ ILRMVRMDRR GGTWKLLGSV VYAHSKELIT AWYIGFLVLI
260 270 280 290 300
FASFLVYLAE KDANSDFSSY ADSLWWGTIT LTTIGYGDKT PHTWLGRVLA
310 320 330 340 350
AGFALLGISF FALPAGILGS GFALKVQEQH RQKHFEKRRM PAANLIQAAW
360 370 380 390 400
RLYSTDMSRA YLTATWYYYD SILPSFRELA LLFEHVQRAR NGGLRPLEVR
410 420 430 440 450
RAPVPDGAPS RYPPVATCHR PGSTSFCPGE SSRMGIKDRI RMGSSQRRTG
460 470 480 490 500
PSKQHLAPPT MPTSPSSEQV GEATSPTKVQ KSWSFNDRTR FRASLRLKPR
510 520 530 540 550
TSAEDAPSEE VAEEKSYQCE LTVDDIMPAV KTVIRSVRIL KFLVAKRKFK
560 570 580 590 600
ETLRPYDVKD VIEQYSAGHL DMLGRIKSLQ TRVDQIVGRG PGDRKAREKG
610 620 630 640 650
DKGPSDAEVV DEISMMGRVV KVEKQVQSIE HKLDLLLGFY SRCLRSGTSA
660 670 680 690
SLGAVQVPLF DPDITSDYHS PVDHEDISVS AQTLSISRSV STNMD
Length:695
Mass (Da):77,087
Last modified:March 21, 2012 - v1
Checksum:iEB8234CE1350F78E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03006109 Genomic DNA. No translation available.
AACZ03006110 Genomic DNA. No translation available.
AACZ03006111 Genomic DNA. No translation available.
RefSeqiXP_513360.2. XM_513360.4.

Genome annotation databases

EnsembliENSPTRT00000001143; ENSPTRP00000001033; ENSPTRG00000000597.
GeneIDi456800.

Similar proteinsi

Entry informationi

Entry nameiH2PYS7_PANTR
AccessioniPrimary (citable) accession number: H2PYS7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 25, 2017
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported