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Protein
Submitted name:

3-hydroxymethyl-3-methylglutaryl-CoA lyase

Gene

HMGCL

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
3-hydroxymethyl-3-methylglutaryl-CoA lyaseImported
Gene namesi
Name:HMGCLImported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSPTRG00000000339.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000000589.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 300Pyruvate carboxyltransferaseInterPro annotationAdd BLAST268

Phylogenomic databases

eggNOGiKOG2368. Eukaryota.
COG0119. LUCA.
GeneTreeiENSGT00390000017690.
KOiK01640.
OMAiFGGCPMA.
OrthoDBiEOG091G0DA9.
TreeFamiTF105363.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiView protein in InterPro
IPR013785. Aldolase_TIM.
IPR000138. HMG_CoA_lyase_AS.
IPR000891. PYR_CT.
PfamiView protein in Pfam
PF00682. HMGL-like. 1 hit.
PROSITEiView protein in PROSITE
PS01062. HMG_COA_LYASE. 1 hit.
PS50991. PYR_CT. 1 hit.

Sequencei

Sequence statusi: Complete.

H2PYB3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAMRKALPR RLVGLASLRA VSTSSMGTLP KRVKIVEVGP RDGLQNEKNI
60 70 80 90 100
VSTPVKIKLV DMLSEAGLSV IETTSFVSPK WVPQMGDHTE VLKGIQKFPG
110 120 130 140 150
INYPVLTPNL KGFEAAVAAG AKEVVIFGAA SELFTKKNIN CSIEESFQRF
160 170 180 190 200
DAILKAAQSA NISVRGYVSC ALGCPYEGKI SPAKVAEVTK KFYSMGCYEI
210 220 230 240 250
SLGDTIGVGT PGIMKDMLSA VMQEVPLAAL AVHCHDTYGQ ALANTLMALQ
260 270 280 290 300
MGVSVVDSSV AGLGGCPYAQ GASGNLATED LVYMLEGLGI HTGVNLQKLL
310 320
EAGNFICQAL NRKTSSKVAQ ATCKL
Length:325
Mass (Da):34,346
Last modified:March 21, 2012 - v1
Checksum:iB82D7667A103A650
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ03010449 Genomic DNA. No translation available.
AACZ03010450 Genomic DNA. No translation available.
AACZ03010451 Genomic DNA. No translation available.
GABF01007958 mRNA. Translation: JAA14187.1.
GABD01009657 mRNA. Translation: JAA23443.1.
RefSeqiXP_001166273.1. XM_001166273.4.

Genome annotation databases

EnsembliENSPTRT00000000664; ENSPTRP00000000589; ENSPTRG00000000339.
GeneIDi456624.
KEGGiptr:456624.

Similar proteinsi

Entry informationi

Entry nameiH2PYB3_PANTR
AccessioniPrimary (citable) accession number: H2PYB3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 25, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported