H2PTF0 (H2PTF0_PONAB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSPPYP00000021980

Gene names

Name:

LMX1B Ensembl ENSPPYP00000021980

Organism

Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) [Reference proteome] Ensembl ENSPPYP00000021980

Taxonomic identifier

9601 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Ponginae › Pongo

Protein attributes

Sequence length	372 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Nucleus By similarity RuleBase RU000682.
Sequence similarities	Contains 1 homeobox DNA-binding domain. SAAS SAAS001781 Contains 2 LIM zinc-binding domains. RuleBase RU000350 SAAS SAAS001781
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSPPYP00000021980

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS001781 RuleBase RU000682
Domain	Homeobox SAAS SAAS001781 RuleBase RU000682 LIM domain RuleBase RU000350 SAAS SAAS001781 Repeat SAAS SAAS001781
Ligand	DNA-binding SAAS SAAS001781 RuleBase RU000682 Metal-binding Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell death Inferred from electronic annotation. Source: Compara cell proliferation Inferred from electronic annotation. Source: Compara central nervous system neuron development Inferred from electronic annotation. Source: Compara cerebellum morphogenesis Inferred from electronic annotation. Source: Compara collagen fibril organization Inferred from electronic annotation. Source: Compara dopaminergic neuron differentiation Inferred from electronic annotation. Source: Compara dorsal/ventral pattern formation Inferred from electronic annotation. Source: Compara limb morphogenesis Inferred from electronic annotation. Source: Compara midbrain development Inferred from electronic annotation. Source: Compara neuron migration Inferred from electronic annotation. Source: Compara organ growth Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara trabecular meshwork development Inferred from electronic annotation. Source: Compara
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	H2PTF0 [UniParc]. Last modified March 21, 2012. Version 1. Checksum: 067106444A850397	FASTA	372	41,594
	10 20 30 40 50 60 MLDGIKMEEH ALRPGPATLG VLLGSDCPHP AVCEGCQRPI SDRFLMRVNE SSWHEECLQC 70 80 90 100 110 120 AACQQALTTS CYFRDRKLYC KQDYQQLFAA KCSGCMEKIA PTEFVMRALE CVYHLGCFCC 130 140 150 160 170 180 CVCERQLRKG DEFVLKEGQL LCKGDYEKEK DLLSSVSPDE SDSVKSEDED GDMKPAKGQG 190 200 210 220 230 240 SQSKGSGDDG KDPRRPKRPR TILTTQQRRA FKASFEVSSK PCRKVRETLA AETGLSVRVV 250 260 270 280 290 300 QVWFQNQRAK MKKLARRHQQ QQEQQNSQRL GQEVLSSRME GMMASYTPLA PPQQQIVAME 310 320 330 340 350 360 QSPYGSSDPF QQGLTPPQMP GNDSIFHDID SDTSLTSLSD CFLGSSDVGS LQARVGNPID 370 RLYSMQSSYF AS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A 6x draft sequence assembly of the Pongo pygmaeus abelii genome." Wilson R.K., Mardis E. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ABGA01375179 Genomic DNA. No translation available. ABGA01375180 Genomic DNA. No translation available. ABGA01375181 Genomic DNA. No translation available. ABGA01375182 Genomic DNA. No translation available. ABGA01375183 Genomic DNA. No translation available. ABGA01375184 Genomic DNA. No translation available. ABGA01375185 Genomic DNA. No translation available. ABGA01375186 Genomic DNA. No translation available. ABGA01375187 Genomic DNA. No translation available.
RefSeq	XP_002820263.1. XM_002820217.2.
3D structure databases
ProteinModelPortal	H2PTF0.
SMR	H2PTF0. Positions 33-150, 191-253.
ModBase	Search...
Proteomic databases
PRIDE	H2PTF0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSPPYT00000022887; ENSPPYP00000021980; ENSPPYG00000019614.
GeneID	100460413.
KEGG	pon:100460413.
Organism-specific databases
CTD	4010.
Phylogenomic databases
GeneTree	ENSGT00700000104050.
KO	K09371.
OMA	NRMEGMM.
Family and domain databases
Gene3D	1.10.10.60. 1 hit. 2.10.110.10. 2 hits.
InterPro	IPR017970. Homeobox_CS. IPR001356. Homeodomain. IPR009057. Homeodomain-like. IPR001781. Znf_LIM. [Graphical view]
Pfam	PF00046. Homeobox. 1 hit. PF00412. LIM. 2 hits. [Graphical view]
SMART	SM00389. HOX. 1 hit. SM00132. LIM. 2 hits. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit.
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. PS00478. LIM_DOMAIN_1. 2 hits. PS50023. LIM_DOMAIN_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

H2PTF0_PONAB

Accession

Primary (citable) accession number: H2PTF0

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2012
Last sequence update:	March 21, 2012
Last modified:	May 1, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)