H2PM86 (H2PM86_PONAB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSPPYP00000019722

Gene names

Name:

GCK Ensembl ENSPPYP00000019722

Organism

Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) [Reference proteome] Ensembl ENSPPYP00000019722

Taxonomic identifier

9601 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Ponginae › Pongo

Protein attributes

Sequence length	464 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities	Belongs to the hexokinase family. RuleBase RU004510
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSPPYP00000019722

Ontologies

Keywords
Biological process	Glycolysis RuleBase RU004049 SAAS SAAS001312
Ligand	ATP-binding RuleBase RU004049 SAAS SAAS001312 Nucleotide-binding
Molecular function	Kinase RuleBase RU004049 SAAS SAAS001312 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	NADP metabolic process Inferred from electronic annotation. Source: Compara calcium ion import Inferred from electronic annotation. Source: Compara cellular glucose homeostasis Inferred from electronic annotation. Source: Compara detection of glucose Inferred from electronic annotation. Source: Compara glucose 6-phosphate metabolic process Inferred from electronic annotation. Source: GOC glycolysis Inferred from electronic annotation. Source: UniProtKB-KW negative regulation of gluconeogenesis Inferred from electronic annotation. Source: Compara positive regulation of glycogen biosynthetic process Inferred from electronic annotation. Source: Compara positive regulation of insulin secretion Inferred from electronic annotation. Source: Compara regulation of potassium ion transport Inferred from electronic annotation. Source: Compara
Cellular_component	mitochondrion Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glucokinase activity Inferred from electronic annotation. Source: Compara glucose binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	H2PM86 [UniParc]. Last modified March 21, 2012. Version 1. Checksum: 9BE5C53B5C91E338	FASTA	464	52,064
	10 20 30 40 50 60 MLDDRARMEA AKEKVEQILA EFQLQEEDLK KVMRRMQKEM DRGLRLETHE EASVKMLPTY 70 80 90 100 110 120 VRSTPEGSEV GDFLSLDLGG TNFRVMLVKV GEGEEGQWSV KTKHQMYSIP EDAMTGTAEM 130 140 150 160 170 180 LFDYISECIS DFLDKHQMKH KKLPLGFTFS FPVRHEDIDK GILLNWTKGF KASGAEGNNV 190 200 210 220 230 240 VGLLRDAIKR RGDFEMDVVA MVNDTVATMI SCYYEDHQCE VGMIVGTGCN ACYMEEMENV 250 260 270 280 290 300 ELVEGDEGRM CVNTEWGAFG DSGELDEFLL EYDRLVDESS ANPGQQLYEK LIGGKYMGEL 310 320 330 340 350 360 VRLVLLRLVD ENLLFHGEAS EQLRTRGAFE TRFVSQVESD TGDRKQIYNI LSTLGLRPST 370 380 390 400 410 420 TDCDIVRRAC ESVSTRAAHM CSAGLAGVIN RMRESRSEDV MRITVGVDGS VYKLHPSFKE 430 440 450 460 RFHASVRRLT PSCEITFIES EEGSGRGAAL VSAVACKKAC MLGQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A 6x draft sequence assembly of the Pongo pygmaeus abelii genome." Wilson R.K., Mardis E. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ABGA01364142 Genomic DNA. No translation available. ABGA01364143 Genomic DNA. No translation available.
RefSeq	XP_002818042.1. XM_002817996.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSPPYT00000020498; ENSPPYP00000019722; ENSPPYG00000017596.
GeneID	100459152.
KEGG	pon:100459152.
Organism-specific databases
CTD	2645.
Phylogenomic databases
GeneTree	ENSGT00390000017159.
KO	K12407.
OMA	ISGKYMG.
Family and domain databases
InterPro	IPR001312. Hexokinase. IPR022673. Hexokinase_C. IPR019807. Hexokinase_CS. IPR022672. Hexokinase_N. [Graphical view]
PANTHER	PTHR19443. PTHR19443. 1 hit.
Pfam	PF00349. Hexokinase_1. 1 hit. PF03727. Hexokinase_2. 1 hit. [Graphical view]
PRINTS	PR00475. HEXOKINASE.
PROSITE	PS00378. HEXOKINASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

H2PM86_PONAB

Accession

Primary (citable) accession number: H2PM86

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2012
Last sequence update:	March 21, 2012
Last modified:	April 3, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)