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Protein

Hexokinase

Gene

HK3

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Name:HK3Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
ProteomesiUP000001595 Componenti: Chromosome 5

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000017995.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000017159.
InParanoidiH2PHH1.
KOiK00844.
OMAiSDCEGQD.
OrthoDBiEOG7S21X5.
TreeFamiTF314238.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H2PHH1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSIGSSGLR QGEEALSCPE EGLPGPSDSS ELVQECLQQF KVTRAQLQQI
60 70 80 90 100
QASLLGSMEQ ALRGQASPAP AVRMLPTYVG STPHGTEQGD FVVLELGATG
110 120 130 140 150
ASLRVLWVTL TGIEGHRVEP RSQEFVIPQE VMLGAGQQLF DFAAHCLSEF
160 170 180 190 200
LDAQPVNKQG LQLGFSFSFP CHQTGLDRST LISWTKGFRC SGVEGQDVVQ
210 220 230 240 250
LLRDAIRRQG AYNIDVVAVV NDTVGTMMGC EPGVRPCEVG LVVDTGTNAC
260 270 280 290 300
YMEEARHVAV LDEDRGRVCV SVEWGSFSDD GALGPVLTTF DHTLDHESLN
310 320 330 340 350
PGAQRFEKMI GGLYLGELVR LVLAHLAQCG VLFGGCTSPA LLSQGSILLE
360 370 380 390 400
HVAEMEDPSA GAARVHAVLQ DLGLSPRASD VELVQHVCAA VCTRAAQLCA
410 420 430 440 450
AALAAVLSCL QHSREQQTLQ VAVATGGRVC ERHPRFCSIL QGTVMLLAPE
460 470 480 490 500
CDVSFIPSAD GGGRGVAMVT AVAARLAAHR RLLEETLAPF RLNHDQLAAV
510 520 530 540 550
QAQMRKAMAK GLRGEASSLR MLPTFVRATP DGSERGDFLA LDLGGTNFRV
560 570 580 590 600
LLVRVTTGVQ ITSQIYSIPE SVAQGSGQQL FDHIVDCIVD FQQKQGLSGQ
610 620 630 640 650
SLPLGFTFSF PCRQLGLDQG ILLNWTKGFN ASDCEGRDVV SLLREAITRR
660 670 680 690 700
QAVELNVVAI VNDTVGTMMS CGYEDPRCEI GLIVGTGTNA CYMEELRNVA
710 720 730 740 750
GVPGDSGRMC INMEWGAFGD DGSLAMLSTR FDASVDQASI NPGKQRFEKM
760 770 780 790 800
ISGMYLGEIV RHILLYLTSL GVLFRGQQTQ RLQTRDIFKT KFLSEIESDS
810 820 830 840 850
LALRQVRAIL EDLGLPLTSD DALMVLEVCQ AVSQRAAQLC GAGVAAVVEK
860 870 880 890 900
IRENRGVEEL AVSVGVDGTL YKLHPHFSSL VAATVRELAP HCVVTFLQSE
910 920
DGSGKGAALV TAVACRLAQL TRV
Length:923
Mass (Da):99,013
Last modified:March 21, 2012 - v1
Checksum:iEC8F3976AD2850F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABGA01362719 Genomic DNA. No translation available.
ABGA01362720 Genomic DNA. No translation available.
RefSeqiXP_002816300.1. XM_002816254.2.

Genome annotation databases

EnsembliENSPPYT00000018714; ENSPPYP00000017995; ENSPPYG00000016080.
GeneIDi100458288.
KEGGipon:100458288.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABGA01362719 Genomic DNA. No translation available.
ABGA01362720 Genomic DNA. No translation available.
RefSeqiXP_002816300.1. XM_002816254.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000017995.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPPYT00000018714; ENSPPYP00000017995; ENSPPYG00000016080.
GeneIDi100458288.
KEGGipon:100458288.

Organism-specific databases

CTDi3101.

Phylogenomic databases

GeneTreeiENSGT00390000017159.
InParanoidiH2PHH1.
KOiK00844.
OMAiSDCEGQD.
OrthoDBiEOG7S21X5.
TreeFamiTF314238.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome."
    Wilson R.K., Mardis E.
    Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiH2PHH1_PONAB
AccessioniPrimary (citable) accession number: H2PHH1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: July 22, 2015
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.