H2PA76 (H2PA76_PONAB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSPPYP00000015320

Gene names

Name:

SETMAR Ensembl ENSPPYP00000015320

Organism

Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) [Reference proteome] Ensembl ENSPPYP00000015320

Taxonomic identifier

9601 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Ponginae › Pongo

Protein attributes

Sequence length	684 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS007728 S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N(6)-methyl-L-lysine.
Subcellular location	Nucleus By similarity.
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 Contains 1 post-SET domain. SAAS SAAS001214 RuleBase RU004541 Contains 1 pre-SET domain. SAAS SAAS007728
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSPPYP00000015320

Ontologies

Keywords
Cellular component	Chromosome SAAS SAAS007728 Nucleus SAAS SAAS007728 RuleBase RU004542
Molecular function	Methyltransferase SAAS SAAS007728 RuleBase RU004541 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA catabolic process, endonucleolytic Inferred from electronic annotation. Source: Compara DNA double-strand break processing Inferred from electronic annotation. Source: Compara DNA integration Inferred from electronic annotation. Source: InterPro negative regulation of cell cycle arrest Inferred from electronic annotation. Source: Compara negative regulation of chromosome organization Inferred from electronic annotation. Source: Compara positive regulation of double-strand break repair via nonhomologous end joining Inferred from electronic annotation. Source: Compara transposition, DNA-mediated Inferred from electronic annotation. Source: InterPro
Cellular_component	chromosome Inferred from electronic annotation. Source: UniProtKB-KW nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	endonuclease activity Inferred from electronic annotation. Source: Compara histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro structure-specific DNA binding Inferred from electronic annotation. Source: Compara transposase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	H2PA76 [UniParc]. Last modified March 21, 2012. Version 1. Checksum: DA995A4A4B24B1ED	FASTA	684	77,995
	10 20 30 40 50 60 MFAEAAKTTR PCGMAEFKEK PEAPTEQLDV ACGQENLPVG AWPPGAAPAP FQYTPDHVVG 70 80 90 100 110 120 PGADIDPTQI TFPGCICVKT PCLPGTCSCL RHGENYDDNS CLRDIGSGGK YAEPVFECNV 130 140 150 160 170 180 LCQCSDHCRN RVVQKGLQFH FQVFKTHKKG WGLRTLEFIS KGRFVCEYAG EVLGFSEVQR 190 200 210 220 230 240 RIHLQTKSDS NYIIAIREHV YNGQVMETFV DPTYIGNIGR FLNHSCEPNL LMIPVRIDSM 250 260 270 280 290 300 VPKLALFAAK DIVPEEELSY DYSGRYLNLT GSEDKERLDN GKLRKPCYCG AKSCTAFLPF 310 320 330 340 350 360 DSSLYCPLEK SNISCGNEKE PSMCGSAPSV FPSCKRLTLE TMKMMLDKKQ IRAIFLFEFK 370 380 390 400 410 420 MGRKAAETTR NINNAFGPGT ANERTVQWWF KKFCKGDESL EDEERSGRPS EVDNDQLRAI 430 440 450 460 470 480 IEADPLTTTR EVAEELNVNH STVVRHLKQI GKVKKLDKWV PHELTENQKN RRFEVSSSLI 490 500 510 520 530 540 LRNHNEPFLD RIVTCDEKWI LYDNRRRSAQ WLDQEEAPKH FPKPILHPKK VMVTIWWSAA 550 560 570 580 590 600 GLIHYSFLNP GETITSEKYA QEIDEMHQKL QRLQLALVNR KGPILLHDNA RPHVAQPTLQ 610 620 630 640 650 660 KLNELGYEVL PHPPYSPDLL PTNYHVFKHL NNFLQGKRFH NQQDAENAFQ EFVKSRSTDF 670 680 YATGINQLIS RWQKCVDCNG SYFD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A 6x draft sequence assembly of the Pongo pygmaeus abelii genome." Wilson R.K., Mardis E. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ABGA01372566 Genomic DNA. No translation available. ABGA01372567 Genomic DNA. No translation available. ABGA01372568 Genomic DNA. No translation available. ABGA01372569 Genomic DNA. No translation available.
RefSeq	XP_002813545.1. XM_002813499.2.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSPPYT00000015930; ENSPPYP00000015320; ENSPPYG00000013699.
GeneID	100447656.
KEGG	pon:100447656.
Organism-specific databases
CTD	6419.
Phylogenomic databases
GeneTree	ENSGT00440000033232.
KO	K11433.
OMA	RRRSAQW.
Family and domain databases
InterPro	IPR003616. Post-SET_dom. IPR007728. Pre-SET_dom. IPR003606. Pre-SET_Zn-bd_sub. IPR001214. SET_dom. IPR001888. Transposase_1. IPR002492. Transposase_Tc1-like. [Graphical view]
Pfam	PF01498. HTH_Tnp_Tc3_2. 1 hit. PF05033. Pre-SET. 1 hit. PF00856. SET. 1 hit. PF01359. Transposase_1. 1 hit. [Graphical view]
SMART	SM00508. PostSET. 1 hit. SM00468. PreSET. 1 hit. SM00317. SET. 1 hit. [Graphical view]
PROSITE	PS50868. POST_SET. 1 hit. PS50867. PRE_SET. 1 hit. PS50280. SET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

H2PA76_PONAB

Accession

Primary (citable) accession number: H2PA76

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2012
Last sequence update:	March 21, 2012
Last modified:	March 6, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)