Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

H2PA76 (H2PA76_PONAB) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length684 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. RuleBase RU004542 SAAS SAAS001214

Subcellular location

Nucleus By similarity RuleBase RU004542.

Sequence similarities

Contains 1 SET domain.

Contains 1 post-SET domain. RuleBase RU004541

Contains 1 pre-SET domain. RuleBase RU004542

Contains SET domain. SAAS SAAS001214

Contains post-SET domain. SAAS SAAS001214

Contains pre-SET domain. SAAS SAAS001214

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSPPYP00000015320

Ontologies

Keywords
   Cellular componentChromosome SAAS SAAS007728
Nucleus RuleBase RU004542 SAAS SAAS001214
   LigandS-adenosyl-L-methionine SAAS SAAS001214
   Molecular functionMethyltransferase RuleBase RU004541 SAAS SAAS001214
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA catabolic process, endonucleolytic

Inferred from electronic annotation. Source: Ensembl

DNA double-strand break processing

Inferred from electronic annotation. Source: Ensembl

DNA integration

Inferred from electronic annotation. Source: InterPro

negative regulation of cell cycle arrest

Inferred from electronic annotation. Source: Ensembl

negative regulation of chromosome organization

Inferred from electronic annotation. Source: Ensembl

positive regulation of double-strand break repair via nonhomologous end joining

Inferred from electronic annotation. Source: Ensembl

transposition, DNA-mediated

Inferred from electronic annotation. Source: InterPro

   Cellular_componentchromosome

Inferred from electronic annotation. Source: UniProtKB-KW

nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionendonuclease activity

Inferred from electronic annotation. Source: Ensembl

histone-lysine N-methyltransferase activity

Inferred from electronic annotation. Source: InterPro

structure-specific DNA binding

Inferred from electronic annotation. Source: Ensembl

transposase activity

Inferred from electronic annotation. Source: InterPro

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
H2PA76 [UniParc].

Last modified March 21, 2012. Version 1.
Checksum: DA995A4A4B24B1ED

FASTA68477,995
        10         20         30         40         50         60 
MFAEAAKTTR PCGMAEFKEK PEAPTEQLDV ACGQENLPVG AWPPGAAPAP FQYTPDHVVG 

        70         80         90        100        110        120 
PGADIDPTQI TFPGCICVKT PCLPGTCSCL RHGENYDDNS CLRDIGSGGK YAEPVFECNV 

       130        140        150        160        170        180 
LCQCSDHCRN RVVQKGLQFH FQVFKTHKKG WGLRTLEFIS KGRFVCEYAG EVLGFSEVQR 

       190        200        210        220        230        240 
RIHLQTKSDS NYIIAIREHV YNGQVMETFV DPTYIGNIGR FLNHSCEPNL LMIPVRIDSM 

       250        260        270        280        290        300 
VPKLALFAAK DIVPEEELSY DYSGRYLNLT GSEDKERLDN GKLRKPCYCG AKSCTAFLPF 

       310        320        330        340        350        360 
DSSLYCPLEK SNISCGNEKE PSMCGSAPSV FPSCKRLTLE TMKMMLDKKQ IRAIFLFEFK 

       370        380        390        400        410        420 
MGRKAAETTR NINNAFGPGT ANERTVQWWF KKFCKGDESL EDEERSGRPS EVDNDQLRAI 

       430        440        450        460        470        480 
IEADPLTTTR EVAEELNVNH STVVRHLKQI GKVKKLDKWV PHELTENQKN RRFEVSSSLI 

       490        500        510        520        530        540 
LRNHNEPFLD RIVTCDEKWI LYDNRRRSAQ WLDQEEAPKH FPKPILHPKK VMVTIWWSAA 

       550        560        570        580        590        600 
GLIHYSFLNP GETITSEKYA QEIDEMHQKL QRLQLALVNR KGPILLHDNA RPHVAQPTLQ 

       610        620        630        640        650        660 
KLNELGYEVL PHPPYSPDLL PTNYHVFKHL NNFLQGKRFH NQQDAENAFQ EFVKSRSTDF 

       670        680 
YATGINQLIS RWQKCVDCNG SYFD 

« Hide

References

« Hide 'large scale' references
[1]"A 6x draft sequence assembly of the Pongo pygmaeus abelii genome."
Wilson R.K., Mardis E.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
ABGA01372566 Genomic DNA. No translation available.
ABGA01372567 Genomic DNA. No translation available.
ABGA01372568 Genomic DNA. No translation available.
ABGA01372569 Genomic DNA. No translation available.
RefSeqXP_002813545.1. XM_002813499.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSPPYT00000015930; ENSPPYP00000015320; ENSPPYG00000013699.
GeneID100447656.
KEGGpon:100447656.

Organism-specific databases

CTD6419.

Phylogenomic databases

GeneTreeENSGT00750000117632.
KOK11433.
OMARRRSAQW.
OrthoDBEOG744T8D.
TreeFamTF352220.

Family and domain databases

InterProIPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR003606. Pre-SET_Zn-bd_sub.
IPR001214. SET_dom.
IPR001888. Transposase_1.
IPR002492. Transposase_Tc1-like.
[Graphical view]
PfamPF01498. HTH_Tnp_Tc3_2. 1 hit.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
PF01359. Transposase_1. 1 hit.
[Graphical view]
SMARTSM00508. PostSET. 1 hit.
SM00468. PreSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEPS50868. POST_SET. 1 hit.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH2PA76_PONAB
AccessionPrimary (citable) accession number: H2PA76
Entry history
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: April 16, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)