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H2PA76

- H2PA76_PONAB

UniProt

H2PA76 - H2PA76_PONAB

Protein
Submitted name:

Uncharacterized protein

Gene

SETMAR

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 14 (01 Oct 2014)
      Sequence version 1 (21 Mar 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

    GO - Molecular functioni

    1. endonuclease activity Source: Ensembl
    2. histone-lysine N-methyltransferase activity Source: InterPro
    3. structure-specific DNA binding Source: Ensembl
    4. transposase activity Source: InterPro
    5. zinc ion binding Source: InterPro

    GO - Biological processi

    1. DNA catabolic process, endonucleolytic Source: Ensembl
    2. DNA double-strand break processing Source: Ensembl
    3. DNA integration Source: InterPro
    4. negative regulation of cell cycle arrest Source: Ensembl
    5. negative regulation of chromosome organization Source: Ensembl
    6. positive regulation of double-strand break repair via nonhomologous end joining Source: Ensembl
    7. transposition, DNA-mediated Source: InterPro

    Keywords - Molecular functioni

    MethyltransferaseUniRule annotationSAAS annotation, Transferase

    Keywords - Ligandi

    S-adenosyl-L-methionineSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:SETMARImported
    OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
    Taxonomic identifieri9601 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
    ProteomesiUP000001595: Chromosome 3

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. chromosome Source: UniProtKB-KW
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    ChromosomeSAAS annotation, NucleusUniRule annotationSAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SET domain.UniRule annotation
    Contains 1 post-SET domain.UniRule annotation
    Contains 1 pre-SET domain.
    Contains SET domain.SAAS annotation
    Contains post-SET domain.SAAS annotation
    Contains pre-SET domain.SAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117632.
    KOiK11433.
    OMAiRRRSAQW.
    OrthoDBiEOG744T8D.
    TreeFamiTF352220.

    Family and domain databases

    InterProiIPR003616. Post-SET_dom.
    IPR007728. Pre-SET_dom.
    IPR003606. Pre-SET_Zn-bd_sub.
    IPR001214. SET_dom.
    IPR001888. Transposase_1.
    IPR002492. Transposase_Tc1-like.
    [Graphical view]
    PfamiPF01498. HTH_Tnp_Tc3_2. 1 hit.
    PF05033. Pre-SET. 1 hit.
    PF00856. SET. 1 hit.
    PF01359. Transposase_1. 1 hit.
    [Graphical view]
    SMARTiSM00508. PostSET. 1 hit.
    SM00468. PreSET. 1 hit.
    SM00317. SET. 1 hit.
    [Graphical view]
    PROSITEiPS50868. POST_SET. 1 hit.
    PS50867. PRE_SET. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H2PA76-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFAEAAKTTR PCGMAEFKEK PEAPTEQLDV ACGQENLPVG AWPPGAAPAP    50
    FQYTPDHVVG PGADIDPTQI TFPGCICVKT PCLPGTCSCL RHGENYDDNS 100
    CLRDIGSGGK YAEPVFECNV LCQCSDHCRN RVVQKGLQFH FQVFKTHKKG 150
    WGLRTLEFIS KGRFVCEYAG EVLGFSEVQR RIHLQTKSDS NYIIAIREHV 200
    YNGQVMETFV DPTYIGNIGR FLNHSCEPNL LMIPVRIDSM VPKLALFAAK 250
    DIVPEEELSY DYSGRYLNLT GSEDKERLDN GKLRKPCYCG AKSCTAFLPF 300
    DSSLYCPLEK SNISCGNEKE PSMCGSAPSV FPSCKRLTLE TMKMMLDKKQ 350
    IRAIFLFEFK MGRKAAETTR NINNAFGPGT ANERTVQWWF KKFCKGDESL 400
    EDEERSGRPS EVDNDQLRAI IEADPLTTTR EVAEELNVNH STVVRHLKQI 450
    GKVKKLDKWV PHELTENQKN RRFEVSSSLI LRNHNEPFLD RIVTCDEKWI 500
    LYDNRRRSAQ WLDQEEAPKH FPKPILHPKK VMVTIWWSAA GLIHYSFLNP 550
    GETITSEKYA QEIDEMHQKL QRLQLALVNR KGPILLHDNA RPHVAQPTLQ 600
    KLNELGYEVL PHPPYSPDLL PTNYHVFKHL NNFLQGKRFH NQQDAENAFQ 650
    EFVKSRSTDF YATGINQLIS RWQKCVDCNG SYFD 684
    Length:684
    Mass (Da):77,995
    Last modified:March 21, 2012 - v1
    Checksum:iDA995A4A4B24B1ED
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    ABGA01372566 Genomic DNA. No translation available.
    ABGA01372567 Genomic DNA. No translation available.
    ABGA01372568 Genomic DNA. No translation available.
    ABGA01372569 Genomic DNA. No translation available.
    RefSeqiXP_002813545.1. XM_002813499.2.

    Genome annotation databases

    EnsembliENSPPYT00000015930; ENSPPYP00000015320; ENSPPYG00000013699.
    GeneIDi100447656.
    KEGGipon:100447656.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    ABGA01372566 Genomic DNA. No translation available.
    ABGA01372567 Genomic DNA. No translation available.
    ABGA01372568 Genomic DNA. No translation available.
    ABGA01372569 Genomic DNA. No translation available.
    RefSeqi XP_002813545.1. XM_002813499.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSPPYT00000015930 ; ENSPPYP00000015320 ; ENSPPYG00000013699 .
    GeneIDi 100447656.
    KEGGi pon:100447656.

    Organism-specific databases

    CTDi 6419.

    Phylogenomic databases

    GeneTreei ENSGT00750000117632.
    KOi K11433.
    OMAi RRRSAQW.
    OrthoDBi EOG744T8D.
    TreeFami TF352220.

    Family and domain databases

    InterProi IPR003616. Post-SET_dom.
    IPR007728. Pre-SET_dom.
    IPR003606. Pre-SET_Zn-bd_sub.
    IPR001214. SET_dom.
    IPR001888. Transposase_1.
    IPR002492. Transposase_Tc1-like.
    [Graphical view ]
    Pfami PF01498. HTH_Tnp_Tc3_2. 1 hit.
    PF05033. Pre-SET. 1 hit.
    PF00856. SET. 1 hit.
    PF01359. Transposase_1. 1 hit.
    [Graphical view ]
    SMARTi SM00508. PostSET. 1 hit.
    SM00468. PreSET. 1 hit.
    SM00317. SET. 1 hit.
    [Graphical view ]
    PROSITEi PS50868. POST_SET. 1 hit.
    PS50867. PRE_SET. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome."
      Wilson R.K., Mardis E.
      Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiH2PA76_PONAB
    AccessioniPrimary (citable) accession number: H2PA76
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 21, 2012
    Last sequence update: March 21, 2012
    Last modified: October 1, 2014
    This is version 14 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3