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Protein

RuvB-like helicase

Gene

RUVBL1

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseUniRule annotationSAAS annotation, Hydrolase
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, Transcription, Transcription regulationUniRule annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RuvB-like helicaseUniRule annotation (EC:3.6.4.12UniRule annotation)
Gene namesi
Name:RUVBL1Imported
ORF Names:CR201_G0032072Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
Proteomesi
  • UP000001595 Componenti: Chromosome 3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000015029.

Structurei

3D structure databases

ProteinModelPortaliH2P9F3.
SMRiH2P9F3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 365AAAInterPro annotationAdd BLAST304

Sequence similaritiesi

Belongs to the RuvB family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1942. Eukaryota.
COG1224. LUCA.
GeneTreeiENSGT00890000139499.
InParanoidiH2P9F3.
KOiK04499.
OMAiDVHKRKE.
OrthoDBiEOG091G07C9.
TreeFamiTF300457.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR027417. P-loop_NTPase.
IPR027238. RuvB-like.
IPR037938. RUVBL1.
IPR010339. TIP49_C.
PANTHERiPTHR11093. PTHR11093. 1 hit.
PTHR11093:SF6. PTHR11093:SF6. 1 hit.
PfamiView protein in Pfam
PF06068. TIP49. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.

Sequencei

Sequence statusi: Complete.

H2P9F3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIEEVKSTT KTQRIASHSH VKGLGLDESG LAKQAASGLV GQENAREACG
60 70 80 90 100
VIVELIKSKK MAGRAVLLAG PPGTGKTALA LAIAQELGSK VPFCPMVGSE
110 120 130 140 150
VYSTEIKKTE VLMENFRRAI GLRIKETKEV YEGEVTELTP CETENPMGGY
160 170 180 190 200
GKTISHVIIG LKTAKGTKQL KLDPSIFESL QKERVEAGDV IYIEANSGAV
210 220 230 240 250
KRQGRCDTYA TEFDLEAEEY VPLPKGDVHK KKEIIQDVTL HDLDVANARP
260 270 280 290 300
QGGQDILSMM GQLMKPKKTE ITDKLRGEIN KVVNKYIDQG IAELVPGVLF
310 320 330 340 350
VDEVHMLDIE CFTYLHRALE SSIAPIVIFA SNRGNCVIRG TEDITSPHGI
360 370 380 390 400
PLDLLDRVMI IRTMLYTPQE MKQIIKIRAQ TEGINISEEA LNHLGEIGTK
410 420 430 440 450
TTLRYSVQLL TPANLLAKIN GKDSIEKEHV EEISELFYDA KSSAKILADQ

QDKYMK
Length:456
Mass (Da):50,228
Last modified:March 21, 2012 - v1
Checksum:i6095ADE692B1482B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABGA01304428 Genomic DNA. No translation available.
ABGA01304429 Genomic DNA. No translation available.
ABGA01304430 Genomic DNA. No translation available.
ABGA01304431 Genomic DNA. No translation available.
ABGA01304432 Genomic DNA. No translation available.
ABGA01304433 Genomic DNA. No translation available.
NDHI03003481 Genomic DNA. Translation: PNJ36965.1.
RefSeqiXP_002813209.2. XM_002813163.3.

Genome annotation databases

EnsembliENSPPYT00000015630; ENSPPYP00000015029; ENSPPYG00000013437.
GeneIDi100462068.
KEGGipon:100462068.

Similar proteinsi

Entry informationi

Entry nameiH2P9F3_PONAB
AccessioniPrimary (citable) accession number: H2P9F3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: March 28, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported