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H2P1W1

- H2P1W1_PONAB

UniProt

H2P1W1 - H2P1W1_PONAB

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Protein
Submitted name: Uncharacterized protein
Gene
TGM2
Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Cofactori

Binds 1 calcium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei277 – 2771 By similarityUniRule annotation
Active sitei335 – 3351 By similarityUniRule annotation
Active sitei358 – 3581 By similarityUniRule annotation
Metal bindingi398 – 3981Calcium By similarity
Metal bindingi400 – 4001Calcium By similarity
Metal bindingi447 – 4471Calcium By similarity
Metal bindingi452 – 4521Calcium By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

GO - Biological processi

  1. apoptotic cell clearance Source: Ensembl
  2. branching involved in salivary gland morphogenesis Source: Ensembl
  3. peptide cross-linking Source: InterPro
  4. positive regulation of cell adhesion Source: Ensembl
  5. salivary gland cavitation Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TGM2Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
ProteomesiUP000001595: Chromosome 20

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00740000115156.
KOiK05625.
OMAiANGRDHH.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H2P1W1-1 [UniParc]FASTAAdd to Basket

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MAEDLVLERC DLELETNGRD HHTADLCREK LVVRRGQPFW LTLHFEGRNY    50
EASVDSLTFS VVTGPAPSQE AGTKARFPLR DAVEEGDWTA TVVDQQDCTL 100
SLQLTTPADA PIGLYRLSLE ASTGYQGSSF VLGHFILLFN SWCPADAVYL 150
DSEEERQEYV LTQQGFIYQG SAKFIKNIPW NFGQFEDGIL DICLMLLDVN 200
PKFLKNAGRD CSRRSSPIYV GRVVSGMVNC NDDQGVLLGR WDNNYGDGIS 250
PMSWIGSVDI LRRWKNHGCQ RVKYGQCWVF AAVACTVLRC LGIPTRVVTN 300
YNSAHDQNSN LLIEYFRNEF GEIQGDKSEM IWNFHCWVES WMTRPDLQPG 350
YEGWQALDPT PQEKSEGTYC CGPVPVRAIK EGDLSTKYDA PFVFAEVNAD 400
VVDWIQQDDG SVHKSINHSL IVGLKISTKS VGRDEREDIT HTYKYPEGSS 450
EEREAFTRAN HLNKLAEKEE TGMAMRIRVG QSMNMGSDFD VFAHITNNTA 500
EEYVCRLLLC ARTVSYNGIL GPECGTKYLL NLNLEPFSEK SVPLCILYEK 550
YRDCLTESNL IKVRALLVEP VINSYLLAER DLYLENPEIK IRILGEPKQK 600
RKLVAEVSLQ NPLPVALEGC TFTVEGAGLT EEQKTVEIPD PVEAGEEVKV 650
RIDLLPLHVG LHKLVVNFES DKLKAVKGFR NVIIGPA 687
Length:687
Mass (Da):77,309
Last modified:January 9, 2013 - v2
Checksum:iB8B8FDA61E38F8E9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ABGA01201687 Genomic DNA. No translation available.
ABGA01201688 Genomic DNA. No translation available.
ABGA01201689 Genomic DNA. No translation available.
ABGA01201690 Genomic DNA. No translation available.
RefSeqiXP_002830335.1. XM_002830289.2.

Genome annotation databases

EnsembliENSPPYT00000012759; ENSPPYP00000012278; ENSPPYG00000010993.
GeneIDi100441290.
KEGGipon:100441290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ABGA01201687 Genomic DNA. No translation available.
ABGA01201688 Genomic DNA. No translation available.
ABGA01201689 Genomic DNA. No translation available.
ABGA01201690 Genomic DNA. No translation available.
RefSeqi XP_002830335.1. XM_002830289.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSPPYT00000012759 ; ENSPPYP00000012278 ; ENSPPYG00000010993 .
GeneIDi 100441290.
KEGGi pon:100441290.

Organism-specific databases

CTDi 7052.

Phylogenomic databases

GeneTreei ENSGT00740000115156.
KOi K05625.
OMAi ANGRDHH.
OrthoDBi EOG7WT40M.
TreeFami TF324278.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome."
    Wilson R.K., Mardis E.
    Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiH2P1W1_PONAB
AccessioniPrimary (citable) accession number: H2P1W1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: January 9, 2013
Last modified: July 9, 2014
This is version 19 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi