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H2P1F0

- H2P1F0_PONAB

UniProt

H2P1F0 - H2P1F0_PONAB

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Protein
Submitted name:

Uncharacterized protein

Gene

TGM3

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cofactori

Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei273 – 2731UniRule annotation
Active sitei331 – 3311UniRule annotation
Active sitei354 – 3541UniRule annotation
Metal bindingi394 – 3941Calcium
Metal bindingi396 – 3961Calcium
Metal bindingi444 – 4441Calcium
Metal bindingi449 – 4491Calcium

GO - Molecular functioni

  1. calcium ion binding Source: Ensembl
  2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

GO - Biological processi

  1. cell envelope organization Source: Ensembl
  2. keratinocyte differentiation Source: Ensembl
  3. peptide cross-linking Source: Ensembl
  4. protein tetramerization Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TGM3Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
ProteomesiUP000001595: Chromosome 20

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. extracellular vesicular exosome Source: Ensembl
  3. extrinsic component of cytoplasmic side of plasma membrane Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119108.
InParanoidiH2P1F0.
KOiK05620.
OMAiEILPTRS.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H2P1F0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAALGVQSVK WQTAFNRQAH HTDKFSSQEL ILRRGQNFQI LMIMNKGLDS
60 70 80 90 100
NERLEFIVST GPYPSESAMT KAVFPLSNGS SGGWSAVLQA SNGNTLTISI
110 120 130 140 150
SSPASAPVGR YTMALQIFSQ GGVSSVKLGT FILLFNPWLN VDSVFMGNHA
160 170 180 190 200
EREEYVQEDA GIIYVGSTNR IGMIGWNFGQ FEEDILSICL SILDRSLNFR
210 220 230 240 250
RDAATDVARR NDPKYVGRVL SAMINSNDDN GVLAGNWSGT YTGGRDPRNW
260 270 280 290 300
NGSVEILKNW KKSGFSPVRY GQCWVFAGTL NTALRSLGIP SRVITNFNSA
310 320 330 340 350
HDTDRNLSVD VYYDPMGNPL DKGSDSVWNF HVWNEGWFVR SDLGPAYGGW
360 370 380 390 400
QVLDATPQER SQGVFQCGPA SVIGVREGDV QLNFDMPFIF AEVNADRITW
410 420 430 440 450
LYDDTTGKQR KNSVNSHAIG RYISTKAVGS NARMDVTEKY KYPEGSDQER
460 470 480 490 500
QVFQKALGKL KPNASFGATS SMGLETEEQE PSIIGKLKVA GMLAVGKEVN
510 520 530 540 550
LVLLLKNLSR DTKTVTVNMT AWTIIYNGTL VHEVWKDSAT MSLDPEEEAE
560 570 580 590 600
HPIKISYAQY EKYLKSDNMI RITAVCKVPD ESEVVVERDI ILDNPTLTLE
610 620 630 640 650
VLNEARVRKP VNVQMLFSNP LDEPVRDCVL MVEGSGLLLG TLKIDVPTLR
660 670 680 690
PKERSRVRFE ILPTRSGTKQ LLADFSCNKF PAIKAMLSID VAE
Length:693
Mass (Da):76,886
Last modified:March 21, 2012 - v1
Checksum:i6A842DEADFADAF5A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ABGA01347326 Genomic DNA. No translation available.
ABGA01347327 Genomic DNA. No translation available.
ABGA01347328 Genomic DNA. No translation available.
RefSeqiXP_002830165.1. XM_002830119.1.

Genome annotation databases

EnsembliENSPPYT00000012587; ENSPPYP00000012109; ENSPPYG00000010843.
GeneIDi100454156.
KEGGipon:100454156.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ABGA01347326 Genomic DNA. No translation available.
ABGA01347327 Genomic DNA. No translation available.
ABGA01347328 Genomic DNA. No translation available.
RefSeqi XP_002830165.1. XM_002830119.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSPPYT00000012587 ; ENSPPYP00000012109 ; ENSPPYG00000010843 .
GeneIDi 100454156.
KEGGi pon:100454156.

Organism-specific databases

CTDi 7053.

Phylogenomic databases

GeneTreei ENSGT00760000119108.
InParanoidi H2P1F0.
KOi K05620.
OMAi EILPTRS.
OrthoDBi EOG7WT40M.
TreeFami TF324278.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome."
    Wilson R.K., Mardis E.
    Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiH2P1F0_PONAB
AccessioniPrimary (citable) accession number: H2P1F0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 29, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3