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Protein
Submitted name:

TGM3 isoform 1

Gene

TGM3

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Cofactori

Ca2+UniRule annotationNote: Binds 1 Ca2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei273UniRule annotation1
Active sitei331UniRule annotation1
Active sitei354UniRule annotation1
Metal bindingi394CalciumUniRule annotation1
Metal bindingi396CalciumUniRule annotation1
Metal bindingi444CalciumUniRule annotation1
Metal bindingi449CalciumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
TGM3 isoform 1Imported
Submitted name:
Transglutaminase 3Imported
Gene namesi
Name:TGM3Imported
ORF Names:CR201_G0018423Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
Proteomesi
  • UP000001595 Componenti: Chromosome 20

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000012109

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini265 – 357TGcInterPro annotationAdd BLAST93

Phylogenomic databases

eggNOGiENOG410IFMV Eukaryota
ENOG410XQEZ LUCA
GeneTreeiENSGT00760000119108
InParanoidiH2P1F0
KOiK05620
OMAiKADNMIR
OrthoDBiEOG091G030K
TreeFamiTF324278

Family and domain databases

Gene3Di2.60.40.10, 3 hits
3.90.260.10, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002931 Transglutaminase-like
IPR036985 Transglutaminase-like_sf
IPR023608 Transglutaminase_animal
IPR013808 Transglutaminase_AS
IPR008958 Transglutaminase_C
IPR036238 Transglutaminase_C_sf
IPR001102 Transglutaminase_N
PfamiView protein in Pfam
PF00927 Transglut_C, 2 hits
PF01841 Transglut_core, 1 hit
PF00868 Transglut_N, 1 hit
PIRSFiPIRSF000459 TGM_EBP42, 1 hit
SMARTiView protein in SMART
SM00460 TGc, 1 hit
SUPFAMiSSF49309 SSF49309, 2 hits
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00547 TRANSGLUTAMINASES, 1 hit

Sequencei

Sequence statusi: Complete.

H2P1F0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAALGVQSVK WQTAFNRQAH HTDKFSSQEL ILRRGQNFQI LMIMNKGLDS
60 70 80 90 100
NERLEFIVST GPYPSESAMT KAVFPLSNGS SGGWSAVLQA SNGNTLTISI
110 120 130 140 150
SSPASAPVGR YTMALQIFSQ GGVSSVKLGT FILLFNPWLN VDSVFMGNHA
160 170 180 190 200
EREEYVQEDA GIIYVGSTNR IGMIGWNFGQ FEEDILSICL SILDRSLNFR
210 220 230 240 250
RDAATDVARR NDPKYVGRVL SAMINSNDDN GVLAGNWSGT YTGGRDPRNW
260 270 280 290 300
NGSVEILKNW KKSGFSPVRY GQCWVFAGTL NTALRSLGIP SRVITNFNSA
310 320 330 340 350
HDTDRNLSVD VYYDPMGNPL DKGSDSVWNF HVWNEGWFVR SDLGPAYGGW
360 370 380 390 400
QVLDATPQER SQGVFQCGPA SVIGVREGDV QLNFDMPFIF AEVNADRITW
410 420 430 440 450
LYDDTTGKQR KNSVNSHAIG RYISTKAVGS NARMDVTEKY KYPEGSDQER
460 470 480 490 500
QVFQKALGKL KPNASFGATS SMGLETEEQE PSIIGKLKVA GMLAVGKEVN
510 520 530 540 550
LVLLLKNLSR DTKTVTVNMT AWTIIYNGTL VHEVWKDSAT MSLDPEEEAE
560 570 580 590 600
HPIKISYAQY EKYLKSDNMI RITAVCKVPD ESEVVVERDI ILDNPTLTLE
610 620 630 640 650
VLNEARVRKP VNVQMLFSNP LDEPVRDCVL MVEGSGLLLG TLKIDVPTLR
660 670 680 690
PKERSRVRFE ILPTRSGTKQ LLADFSCNKF PAIKAMLSID VAE
Length:693
Mass (Da):76,886
Last modified:March 21, 2012 - v1
Checksum:i6A842DEADFADAF5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABGA01347326 Genomic DNA No translation available.
ABGA01347327 Genomic DNA No translation available.
ABGA01347328 Genomic DNA No translation available.
NDHI03003419 Genomic DNA Translation: PNJ57196.1
RefSeqiXP_002830165.1, XM_002830119.1

Genome annotation databases

EnsembliENSPPYT00000012587; ENSPPYP00000012109; ENSPPYG00000010843
GeneIDi100454156
KEGGipon:100454156

Similar proteinsi

Entry informationi

Entry nameiH2P1F0_PONAB
AccessioniPrimary (citable) accession number: H2P1F0
Secondary accession number(s): A0A2J8VI49
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: May 23, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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