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H2P1F0

- H2P1F0_PONAB

UniProt

H2P1F0 - H2P1F0_PONAB

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Protein
Submitted name: Uncharacterized protein
Gene
TGM3
Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Cofactori

Binds 1 calcium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei273 – 2731 By similarityUniRule annotation
Active sitei331 – 3311 By similarityUniRule annotation
Active sitei354 – 3541 By similarityUniRule annotation
Metal bindingi394 – 3941Calcium By similarityUniRule annotation
Metal bindingi396 – 3961Calcium By similarityUniRule annotation
Metal bindingi444 – 4441Calcium By similarityUniRule annotation
Metal bindingi449 – 4491Calcium By similarityUniRule annotation

GO - Molecular functioni

  1. GDP binding Source: Ensembl
  2. GTP binding Source: Ensembl
  3. GTPase activity Source: Ensembl
  4. calcium ion binding Source: Ensembl
  5. magnesium ion binding Source: Ensembl
  6. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

GO - Biological processi

  1. cell envelope organization Source: Ensembl
  2. keratinocyte differentiation Source: Ensembl
  3. peptide cross-linking Source: Ensembl
  4. protein tetramerization Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TGM3Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
ProteomesiUP000001595: Chromosome 20

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. extrinsic component of cytoplasmic side of plasma membrane Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00740000115034.
KOiK05620.
OMAiEILPTRS.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H2P1F0-1 [UniParc]FASTAAdd to Basket

« Hide

MAALGVQSVK WQTAFNRQAH HTDKFSSQEL ILRRGQNFQI LMIMNKGLDS    50
NERLEFIVST GPYPSESAMT KAVFPLSNGS SGGWSAVLQA SNGNTLTISI 100
SSPASAPVGR YTMALQIFSQ GGVSSVKLGT FILLFNPWLN VDSVFMGNHA 150
EREEYVQEDA GIIYVGSTNR IGMIGWNFGQ FEEDILSICL SILDRSLNFR 200
RDAATDVARR NDPKYVGRVL SAMINSNDDN GVLAGNWSGT YTGGRDPRNW 250
NGSVEILKNW KKSGFSPVRY GQCWVFAGTL NTALRSLGIP SRVITNFNSA 300
HDTDRNLSVD VYYDPMGNPL DKGSDSVWNF HVWNEGWFVR SDLGPAYGGW 350
QVLDATPQER SQGVFQCGPA SVIGVREGDV QLNFDMPFIF AEVNADRITW 400
LYDDTTGKQR KNSVNSHAIG RYISTKAVGS NARMDVTEKY KYPEGSDQER 450
QVFQKALGKL KPNASFGATS SMGLETEEQE PSIIGKLKVA GMLAVGKEVN 500
LVLLLKNLSR DTKTVTVNMT AWTIIYNGTL VHEVWKDSAT MSLDPEEEAE 550
HPIKISYAQY EKYLKSDNMI RITAVCKVPD ESEVVVERDI ILDNPTLTLE 600
VLNEARVRKP VNVQMLFSNP LDEPVRDCVL MVEGSGLLLG TLKIDVPTLR 650
PKERSRVRFE ILPTRSGTKQ LLADFSCNKF PAIKAMLSID VAE 693
Length:693
Mass (Da):76,886
Last modified:March 21, 2012 - v1
Checksum:i6A842DEADFADAF5A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ABGA01347326 Genomic DNA. No translation available.
ABGA01347327 Genomic DNA. No translation available.
ABGA01347328 Genomic DNA. No translation available.
RefSeqiXP_002830165.1. XM_002830119.1.

Genome annotation databases

EnsembliENSPPYT00000012587; ENSPPYP00000012109; ENSPPYG00000010843.
GeneIDi100454156.
KEGGipon:100454156.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ABGA01347326 Genomic DNA. No translation available.
ABGA01347327 Genomic DNA. No translation available.
ABGA01347328 Genomic DNA. No translation available.
RefSeqi XP_002830165.1. XM_002830119.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSPPYT00000012587 ; ENSPPYP00000012109 ; ENSPPYG00000010843 .
GeneIDi 100454156.
KEGGi pon:100454156.

Organism-specific databases

CTDi 7053.

Phylogenomic databases

GeneTreei ENSGT00740000115034.
KOi K05620.
OMAi EILPTRS.
OrthoDBi EOG7WT40M.
TreeFami TF324278.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome."
    Wilson R.K., Mardis E.
    Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiH2P1F0_PONAB
AccessioniPrimary (citable) accession number: H2P1F0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: July 9, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi