Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cytochrome P450 family 2 subfamily S member 1

Gene

CYP2S1

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 family 2 subfamily S member 1Imported
Gene namesi
Name:CYP2S1Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
Proteomesi
  • UP000001595 Componenti: Chromosome 19

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei294 – 317HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_500356655027 – 563Sequence analysisAdd BLAST537

Interactioni

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000011204.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
GeneTreeiENSGT00880000137861.
InParanoidiH2NYX1.
OMAiQLRKFTM.
OrthoDBiEOG091G0BT8.
TreeFamiTF352043.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR008067. Cyt_P450_E_grp-I_CYP2A-like.
IPR036396. Cyt_P450_sf.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00463. EP450I.
PR01684. EP450ICYP2A.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.

Sequencei

Sequence statusi: Complete.

H2NYX1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEATGTWALL LALLLLLTLA LSGTRARGHL PPGPTPLPLL GNLLQLRPGA
60 70 80 90 100
LYSGLMRLSK KYGPVFTIYL GPWRPVVVLV GQEAVREALG GQAEEFSGRG
110 120 130 140 150
TVAMLERTFD GHGVFFSNGE RWRQLRKFTM LALRDLGMGK REGEELIQAE
160 170 180 190 200
ARCLVEAFQG TEGRPFDPSL LLAQATSNVV CSLLFGLRFS YEDKEFQAVV
210 220 230 240 250
QAAGGTLLGV SSRGGQTYEM FSWFLRPLPG PHKQLLHHVS TLAAFTVRQV
260 270 280 290 300
QQHQGNLDAS GPARDLVDAF LLKMAQEEQN PDTEFTNKNM LMTVIYLLFA
310 320 330 340 350
GTMTVSATVG YTLLLLMKYP HVQKRVREEL NRELGAGQAP SLGDRTRLPY
360 370 380 390 400
TDAVLHEAQR LLALVPMGIP RTLMRTTHFR GYTLPQGTEV FPLLGSILHD
410 420 430 440 450
PNIFKHPEEF NPDRMLDADG RFRKHEAFLP FSLGKRVCLG EGLAKAELFL
460 470 480 490 500
FFTTILQAFS LESPCPPGTL SLKPTISGLF NIPPASTVGM DRVNVSRVYT
510 520 530 540 550
VGSHIYTPAA VFRSLSHGPH THLTHAAVKM HNHTPIHNYK GHKATAALAF
560
HRHKYTPSAI TST
Length:563
Mass (Da):62,173
Last modified:March 21, 2012 - v1
Checksum:iB00EA3C0E58F686B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABGA01395126 Genomic DNA. No translation available.
ABGA01395127 Genomic DNA. No translation available.
ABGA01395128 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSPPYT00000011642; ENSPPYP00000011204; ENSPPYG00000010009.

Similar proteinsi

Entry informationi

Entry nameiH2NYX1_PONAB
AccessioniPrimary (citable) accession number: H2NYX1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 25, 2017
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported