H2NP64 (H2NP64_PONAB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSPPYP00000007685

Gene names

Name:

IDH2 Ensembl ENSPPYP00000007685

Organism

Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) [Reference proteome] Ensembl ENSPPYP00000007685

Taxonomic identifier

9601 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Ponginae › Pongo

Protein attributes

Sequence length	574 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities	Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSPPYP00000007685

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004444
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	isocitrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	mitochondrial inner membrane Inferred from electronic annotation. Source: Compara
Molecular_function	NAD binding Inferred from electronic annotation. Source: InterPro isocitrate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	H2NP64 [UniParc]. Last modified January 9, 2013. Version 2. Checksum: 738C607EC0506A24	FASTA	574	63,273
	10 20 30 40 50 60 MLERVSLASG SANPPALIPL AGPGGSHACS SCGAGISAAP REEPAGPGRR VPTPAGRWTR 70 80 90 100 110 120 RRPWPRLLPG KAQWGGGPGS PAPVVSARPA PARPSVNPRS GSREERRALG PLPPCLFALL 130 140 150 160 170 180 LGMAGYLRVV RSLCRASGSR PAWAPAALTA PTSQEQPRRH YADRRIKVAK PVVEMDGDEM 190 200 210 220 230 240 TRIIWQFIKE KLILPHVDIQ LKYFDLGLPN RDQTDDQVTI DSALATQKYS VAVKCATITP 250 260 270 280 290 300 DEARVEEFKL KKMWKSPNGT IRNILGGTVF REPIICKNIP RLVPGWTKPI TIGRHAHGDQ 310 320 330 340 350 360 YKATDFVADR AGTFKMVFTP KDGSGVKEWE VYNFPAGGVG VGMYNTDESI SGFAHSCFQY 370 380 390 400 410 420 AIQKKWPLYM STKNTILKAY DGRFKDIFQE IFDKHYKTDF DKNKIWYEHR LIDDMVAQVL 430 440 450 460 470 480 KSSGGFVWAC KNYDGDVQSD ILAQGFGSLG LMTSVLVCPD GKTIEAEAAH GTVTRHYREH 490 500 510 520 530 540 QKGRPTSTNP IASIFAWTRG LEHRGKLDGN QDLIRFAQTL EKVCVETVES GAMTKDLAGC 550 560 570 IHGLSNVKLN EHFLNTTDFL DTIKSNLDRA LGRQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A 6x draft sequence assembly of the Pongo pygmaeus abelii genome." Wilson R.K., Mardis E. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ABGA01164031 Genomic DNA. No translation available. ABGA01164032 Genomic DNA. No translation available. ABGA01164033 Genomic DNA. No translation available. ABGA01164034 Genomic DNA. No translation available.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSPPYT00000007998; ENSPPYP00000007685; ENSPPYG00000006775.
Phylogenomic databases
OMA	QHQQGKP.
Family and domain databases
Gene3D	3.40.718.10. 1 hit.
InterPro	IPR019818. IsoCit/isopropylmalate_DH_CS. IPR004790. Isocitrate_DH_NADP. IPR024084. IsoPropMal-DH-like_dom. [Graphical view]
PANTHER	PTHR11822. PTHR11822. 1 hit.
Pfam	PF00180. Iso_dh. 1 hit. [Graphical view]
TIGRFAMs	TIGR00127. nadp_idh_euk. 1 hit.
PROSITE	PS00470. IDH_IMDH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

H2NP64_PONAB

Accession

Primary (citable) accession number: H2NP64

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2012
Last sequence update:	January 9, 2013
Last modified:	May 1, 2013
This is version 12 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)