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H2NP64

- H2NP64_PONAB

UniProt

H2NP64 - H2NP64_PONAB

Protein
Submitted name:

Uncharacterized protein

Gene

IDH2

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 2 (09 Jan 2013)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. isocitrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:IDH2Imported
    OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
    Taxonomic identifieri9601 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
    ProteomesiUP000001595: Chromosome 15

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrial inner membrane Source: Ensembl

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00390000012547.
    OMAiCFQYAIG.
    OrthoDBiEOG7QNVKS.
    TreeFamiTF300428.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR004790. Isocitrate_DH_NADP.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11822. PTHR11822. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00127. nadp_idh_euk. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H2NP64-1 [UniParc]FASTAAdd to Basket

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    MLERVSLASG SANPPALIPL AGPGGSHACS SCGAGISAAP REEPAGPGRR    50
    VPTPAGRWTR RRPWPRLLPG KAQWGGGPGS PAPVVSARPA PARPSVNPRS 100
    GSREERRALG PLPPCLFALL LGMAGYLRVV RSLCRASGSR PAWAPAALTA 150
    PTSQEQPRRH YADRRIKVAK PVVEMDGDEM TRIIWQFIKE KLILPHVDIQ 200
    LKYFDLGLPN RDQTDDQVTI DSALATQKYS VAVKCATITP DEARVEEFKL 250
    KKMWKSPNGT IRNILGGTVF REPIICKNIP RLVPGWTKPI TIGRHAHGDQ 300
    YKATDFVADR AGTFKMVFTP KDGSGVKEWE VYNFPAGGVG VGMYNTDESI 350
    SGFAHSCFQY AIQKKWPLYM STKNTILKAY DGRFKDIFQE IFDKHYKTDF 400
    DKNKIWYEHR LIDDMVAQVL KSSGGFVWAC KNYDGDVQSD ILAQGFGSLG 450
    LMTSVLVCPD GKTIEAEAAH GTVTRHYREH QKGRPTSTNP IASIFAWTRG 500
    LEHRGKLDGN QDLIRFAQTL EKVCVETVES GAMTKDLAGC IHGLSNVKLN 550
    EHFLNTTDFL DTIKSNLDRA LGRQ 574
    Length:574
    Mass (Da):63,273
    Last modified:January 9, 2013 - v2
    Checksum:i738C607EC0506A24
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    ABGA01164031 Genomic DNA. No translation available.
    ABGA01164032 Genomic DNA. No translation available.
    ABGA01164033 Genomic DNA. No translation available.
    ABGA01164034 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSPPYT00000007998; ENSPPYP00000007685; ENSPPYG00000006775.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    ABGA01164031 Genomic DNA. No translation available.
    ABGA01164032 Genomic DNA. No translation available.
    ABGA01164033 Genomic DNA. No translation available.
    ABGA01164034 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSPPYT00000007998 ; ENSPPYP00000007685 ; ENSPPYG00000006775 .

    Phylogenomic databases

    GeneTreei ENSGT00390000012547.
    OMAi CFQYAIG.
    OrthoDBi EOG7QNVKS.
    TreeFami TF300428.

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR004790. Isocitrate_DH_NADP.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11822. PTHR11822. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00127. nadp_idh_euk. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome."
      Wilson R.K., Mardis E.
      Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiH2NP64_PONAB
    AccessioniPrimary (citable) accession number: H2NP64
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 21, 2012
    Last sequence update: January 9, 2013
    Last modified: October 1, 2014
    This is version 18 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3