H2NN08 (H2NN08_PONAB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSPPYP00000007261

Gene names

Name:

TGM5 Ensembl ENSPPYP00000007261

Organism

Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) [Reference proteome] Ensembl ENSPPYP00000007261

Taxonomic identifier

9601 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Ponginae › Pongo

Protein attributes

Sequence length	720 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Binds 1 calcium ion per subunit By similarity. PIRSR PIRSR000459-2
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSPPYP00000007261

Ontologies

Keywords
Ligand	Calcium PIRSR PIRSR000459-2 Metal-binding PIRSR PIRSR000459-2
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	peptide cross-linking Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	278	1	By similarity PIRSR PIRSR000459-1
	Active site	337	1	By similarity PIRSR PIRSR000459-1
	Active site	360	1	By similarity PIRSR PIRSR000459-1
	Metal binding	400	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	402	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	448	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	453	1	Calcium By similarity PIRSR PIRSR000459-2

Sequences

	Sequence		Length	Mass (Da)
	H2NN08 [UniParc]. Last modified March 21, 2012. Version 1. Checksum: EF709B08A8FFE719	FASTA	720	80,948
	10 20 30 40 50 60 MAQGLEVALT DLQSSRNNVR HHTEEIAVDH LLVRRGQAFN LTLYFRNRGF QPGLDNIIFV 70 80 90 100 110 120 VETGPLPDLA LGTRAVFSLA RHHSPSPWIA WLETNEATST EVSLCAPPTA AVGRYLLKIH 130 140 150 160 170 180 IDSFQGSVTA YQLGEFILLF NPWCPEDAVY LDSEPQRQEY VMNDYGFIYQ GSKNWIRPCP 190 200 210 220 230 240 WNYGQFEEKI IDICLKLLDK SLHFQTDSAT DCALRGSPVY ISRVVCAMIN SNDDNGVLNG 250 260 270 280 290 300 NWSENYTDGA NPAEWTGSVA ILKQWYATGC QPVRYGQCWV FAAVMCTVMR CLGIPTRVIT 310 320 330 340 350 360 NFDSGHDTDG NLIIDEYYDN TGRILGNKKK DTIWNFHVWN ECWMARKDLP PGYGGWQVLD 370 380 390 400 410 420 ATPQEMSNGV YCCGPASVRA VKEGEVDLNY DTPFVFSMVN ADCMSWLVQG GKEQKLHQDT 430 440 450 460 470 480 SSVGNFISTK SIQSDERDDI TENYKYEEGS LQERQVFLKA LQKLKARRFH GSQRGAELQP 490 500 510 520 530 540 SRPTPLSQDS PRSLHTPSLR PSDVVQVSLK FKLLDPPNMG QDICFVLLAL NMSSQFKDLK 550 560 570 580 590 600 VNLSAQSLLH DGSPLSPFWQ DIAFITLSPK EAKTYPCKIS YSQYSQYLST DKLIRISALG 610 620 630 640 650 660 EEKSSPEKIL VNKIITLSYP SITINVLGAA VVNQPLSIQV IFSNPLSEQV EDCVLTVEGS 670 680 690 700 710 720 GLFKKQQKVF LGVLKPQHRA SIILETVPFK SGQRQIQANM RSNKFKDIKG YRNVYVDFAL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A 6x draft sequence assembly of the Pongo pygmaeus abelii genome." Wilson R.K., Mardis E. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ABGA01108661 Genomic DNA. No translation available.
RefSeq	XP_002825414.1. XM_002825368.2.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSPPYT00000007562; ENSPPYP00000007261; ENSPPYG00000006408.
GeneID	100459707.
KEGG	pon:100459707.
Organism-specific databases
CTD	9333.
Phylogenomic databases
GeneTree	ENSGT00690000101863.
KO	K05622.
OMA	PAEWTGS.
Family and domain databases
Gene3D	2.60.40.10. 3 hits.
InterPro	IPR023608. Gln_gamma-glutamylTfrase_euk. IPR013783. Ig-like_fold. IPR014756. Ig_E-set. IPR002931. Transglutaminase-like. IPR008958. Transglutaminase_C. IPR013808. Transglutaminase_CS. IPR001102. Transglutaminase_N. [Graphical view]
PANTHER	PTHR11590. PTHR11590. 1 hit.
Pfam	PF00927. Transglut_C. 2 hits. PF01841. Transglut_core. 1 hit. PF00868. Transglut_N. 1 hit. [Graphical view]
PIRSF	PIRSF000459. TGM_EBP42. 1 hit.
SMART	SM00460. TGc. 1 hit. [Graphical view]
SUPFAM	SSF81296. Ig_E-set. 1 hit. SSF49309. Transglut_C. 2 hits.
PROSITE	PS00547. TRANSGLUTAMINASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

H2NN08_PONAB

Accession

Primary (citable) accession number: H2NN08

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2012
Last sequence update:	March 21, 2012
Last modified:	March 6, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)