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H2NKW2

- H2NKW2_PONAB

UniProt

H2NKW2 - H2NKW2_PONAB

Protein
Submitted name:

Uncharacterized protein

Gene

TGM1

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (21 Mar 2012)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 calcium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei378 – 3781UniRule annotation
    Active sitei437 – 4371UniRule annotation
    Active sitei460 – 4601UniRule annotation
    Metal bindingi500 – 5001CalciumUniRule annotation
    Metal bindingi502 – 5021CalciumUniRule annotation
    Metal bindingi549 – 5491CalciumUniRule annotation
    Metal bindingi554 – 5541CalciumUniRule annotation

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

    GO - Biological processi

    1. keratinocyte differentiation Source: Ensembl
    2. organ morphogenesis Source: Ensembl
    3. peptide cross-linking Source: InterPro

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:TGM1Imported
    OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
    Taxonomic identifieri9601 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
    ProteomesiUP000001595: Chromosome 14

    Subcellular locationi

    GO - Cellular componenti

    1. cell-cell adherens junction Source: Ensembl
    2. intrinsic component of membrane Source: Ensembl

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00740000115156.
    KOiK05619.
    OMAiGRWGGNP.
    OrthoDBiEOG7WT40M.
    TreeFamiTF324278.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view]
    PANTHERiPTHR11590. PTHR11590. 1 hit.
    PfamiPF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
    SMARTiSM00460. TGc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H2NKW2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMDGPRSDVG RWGGNPLQPP TTPSPEPEPE PDRRSRRGGG GRSFWARCCG    50
    CCSCRNAADD DWGPEPSDSR GRGSSSGTRR PGSRGSDSRR PVSRGSGVNA 100
    AGDGTIQEGM LVVNGVDLLS SRSDQNRREH HTDEYEYDEL IVRRGQPFHM 150
    LLLLSRTYES SDRITLELLI GNNPEVGKGT HVIIPVGKGG SGGWKAQVVK 200
    ASGQNLNLRV HTSPNAIIGK FQFTVRTQSD AGEFQLPFDP RNEIYILFNP 250
    WCPEDIVYVD HEDWRQEYVL NESGRIYYGT EAQIGERTWN YGQFDHGVLD 300
    ACLYILDRRG MPYGGRGDPV SVSRVISAMV NSLDDNGVLI GNWSGDYSRG 350
    TNPSAWVGSV EILLSYLRTG YSVPYGQCWV FAGVTTTVLR CLGLATRTVT 400
    NFNSAHDTDT SLTMDIYFDE NMKPLEHLNH DSVWNFHVWN DCWMKRPDLP 450
    SGFDGWQVVD ATPQETSSGI FCCGPCSVES IKNGLVYMKY DTPFIFAEVN 500
    SDKVYWQRQD DGSFKIVYVE EKAIGTLIVT KAIGSNMRED ITYLYKHPEG 550
    SDAERKAVET AAAHGSKPNV YANRGSAEDV AMQVEAQDAV MGQDLMVSVM 600
    LTNHSSSRRT VKLHLYLSVT FYTGVSGTIF KETKKEVELA PGASDRVTMP 650
    VAYEEYRPHL VDQGAMLLNV SGHVKESGQV LAKQHTFRLR TPDLSLTLLG 700
    AAVVGQECEV QIVFKNPLPV TLTNVVFRLE GSGLQRPKIL NVGDIGGNET 750
    VTLRQTFVPV RPGPRQLIAS LDSPQLSQVH GVIQVDVAPA PRDGGFFSDA 800
    GGDSHLGETI PMASRGGA 818
    Length:818
    Mass (Da):89,960
    Last modified:March 21, 2012 - v1
    Checksum:iC1972B6948EAD967
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    ABGA01219945 Genomic DNA. No translation available.
    ABGA01219946 Genomic DNA. No translation available.
    RefSeqiXP_002824650.1. XM_002824604.2.

    Genome annotation databases

    EnsembliENSPPYT00000006732; ENSPPYP00000006477; ENSPPYG00000005695.
    GeneIDi100457869.
    KEGGipon:100457869.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    ABGA01219945 Genomic DNA. No translation available.
    ABGA01219946 Genomic DNA. No translation available.
    RefSeqi XP_002824650.1. XM_002824604.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSPPYT00000006732 ; ENSPPYP00000006477 ; ENSPPYG00000005695 .
    GeneIDi 100457869.
    KEGGi pon:100457869.

    Organism-specific databases

    CTDi 7051.

    Phylogenomic databases

    GeneTreei ENSGT00740000115156.
    KOi K05619.
    OMAi GRWGGNP.
    OrthoDBi EOG7WT40M.
    TreeFami TF324278.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view ]
    PANTHERi PTHR11590. PTHR11590. 1 hit.
    Pfami PF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
    SMARTi SM00460. TGc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome."
      Wilson R.K., Mardis E.
      Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiH2NKW2_PONAB
    AccessioniPrimary (citable) accession number: H2NKW2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 21, 2012
    Last sequence update: March 21, 2012
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3