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Protein
Submitted name:

Transglutaminase 1

Gene

TGM1

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Cofactori

Ca2+UniRule annotationNote: Binds 1 Ca2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei378UniRule annotation1
Active sitei437UniRule annotation1
Active sitei460UniRule annotation1
Metal bindingi500CalciumUniRule annotation1
Metal bindingi502CalciumUniRule annotation1
Metal bindingi549CalciumUniRule annotation1
Metal bindingi554CalciumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Transglutaminase 1Imported
Gene namesi
Name:TGM1Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
Proteomesi
  • UP000001595 Componenti: Chromosome 14

Subcellular locationi

Interactioni

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000006477

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini370 – 463TGcInterPro annotationAdd BLAST94

Phylogenomic databases

eggNOGiENOG410IFMV Eukaryota
ENOG410XQEZ LUCA
GeneTreeiENSGT00760000119108
InParanoidiH2NKW2
KOiK05619
OMAiNMREDIT
OrthoDBiEOG091G030K
TreeFamiTF324278

Family and domain databases

Gene3Di2.60.40.10, 3 hits
3.90.260.10, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002931 Transglutaminase-like
IPR036985 Transglutaminase-like_sf
IPR023608 Transglutaminase_animal
IPR013808 Transglutaminase_AS
IPR008958 Transglutaminase_C
IPR036238 Transglutaminase_C_sf
IPR001102 Transglutaminase_N
PfamiView protein in Pfam
PF00927 Transglut_C, 2 hits
PF01841 Transglut_core, 1 hit
PF00868 Transglut_N, 1 hit
PIRSFiPIRSF000459 TGM_EBP42, 1 hit
SMARTiView protein in SMART
SM00460 TGc, 1 hit
SUPFAMiSSF49309 SSF49309, 2 hits
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00547 TRANSGLUTAMINASES, 1 hit

Sequencei

Sequence statusi: Complete.

H2NKW2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMDGPRSDVG RWGGNPLQPP TTPSPEPEPE PDRRSRRGGG GRSFWARCCG
60 70 80 90 100
CCSCRNAADD DWGPEPSDSR GRGSSSGTRR PGSRGSDSRR PVSRGSGVNA
110 120 130 140 150
AGDGTIQEGM LVVNGVDLLS SRSDQNRREH HTDEYEYDEL IVRRGQPFHM
160 170 180 190 200
LLLLSRTYES SDRITLELLI GNNPEVGKGT HVIIPVGKGG SGGWKAQVVK
210 220 230 240 250
ASGQNLNLRV HTSPNAIIGK FQFTVRTQSD AGEFQLPFDP RNEIYILFNP
260 270 280 290 300
WCPEDIVYVD HEDWRQEYVL NESGRIYYGT EAQIGERTWN YGQFDHGVLD
310 320 330 340 350
ACLYILDRRG MPYGGRGDPV SVSRVISAMV NSLDDNGVLI GNWSGDYSRG
360 370 380 390 400
TNPSAWVGSV EILLSYLRTG YSVPYGQCWV FAGVTTTVLR CLGLATRTVT
410 420 430 440 450
NFNSAHDTDT SLTMDIYFDE NMKPLEHLNH DSVWNFHVWN DCWMKRPDLP
460 470 480 490 500
SGFDGWQVVD ATPQETSSGI FCCGPCSVES IKNGLVYMKY DTPFIFAEVN
510 520 530 540 550
SDKVYWQRQD DGSFKIVYVE EKAIGTLIVT KAIGSNMRED ITYLYKHPEG
560 570 580 590 600
SDAERKAVET AAAHGSKPNV YANRGSAEDV AMQVEAQDAV MGQDLMVSVM
610 620 630 640 650
LTNHSSSRRT VKLHLYLSVT FYTGVSGTIF KETKKEVELA PGASDRVTMP
660 670 680 690 700
VAYEEYRPHL VDQGAMLLNV SGHVKESGQV LAKQHTFRLR TPDLSLTLLG
710 720 730 740 750
AAVVGQECEV QIVFKNPLPV TLTNVVFRLE GSGLQRPKIL NVGDIGGNET
760 770 780 790 800
VTLRQTFVPV RPGPRQLIAS LDSPQLSQVH GVIQVDVAPA PRDGGFFSDA
810
GGDSHLGETI PMASRGGA
Length:818
Mass (Da):89,960
Last modified:March 21, 2012 - v1
Checksum:iC1972B6948EAD967
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABGA01219945 Genomic DNA No translation available.
ABGA01219946 Genomic DNA No translation available.
RefSeqiXP_002824650.1, XM_002824604.2

Genome annotation databases

EnsembliENSPPYT00000006732; ENSPPYP00000006477; ENSPPYG00000005695
GeneIDi100457869
KEGGipon:100457869

Similar proteinsi

Entry informationi

Entry nameiH2NKW2_PONAB
AccessioniPrimary (citable) accession number: H2NKW2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: April 25, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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