Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein phosphatase methylesterase 1

Gene

PPME1

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Demethylates proteins that have been reversibly carboxymethylated.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei156UniRule annotation1
Active sitei181UniRule annotation1
Active sitei349UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Serine esteraseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein phosphatase methylesterase 1UniRule annotation (EC:3.1.1.-UniRule annotation)
Short name:
PME-1UniRule annotation
Gene namesi
Name:PPME1Imported
ORF Names:CR201_G0023324Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
Proteomesi
  • UP000001595 Componenti: Chromosome 11

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliH2NEM5
SMRiH2NEM5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 362AB hydrolase-1InterPro annotationAdd BLAST284

Sequence similaritiesi

Belongs to the AB hydrolase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG2564 Eukaryota
COG0596 LUCA
GeneTreeiENSGT00390000004396
OMAiRIQCRIV
OrthoDBiEOG091G0D0P
TreeFamiTF314697

Family and domain databases

InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR000073 AB_hydrolase_1
IPR016812 PPase_methylesterase_euk
PANTHERiPTHR14189 PTHR14189, 1 hit
PfamiView protein in Pfam
PF12697 Abhydrolase_6, 1 hit
PIRSFiPIRSF022950 PPase_methylesterase_euk, 1 hit
SUPFAMiSSF53474 SSF53474, 2 hits

Sequencei

Sequence statusi: Complete.

H2NEM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSALEKSMHL GRLPSRPPLP GSGGSQSGAK MRMGPGRKRD FSPVPWSQYF
60 70 80 90 100
ESMEDVEVEN ETGKDTFRVY KSGSEGPVLL LLHGGGHSAL SWAVFTAAII
110 120 130 140 150
SRVQCRIVAL DLRSHGETKV KNPEDLSAET MAKDVGNVVE AMYGDLPPPI
160 170 180 190 200
MLIGHSMGGA IAVHTASSNL VPSLLGLCMI DVVEGTAMDA LNSMQNFLRG
210 220 230 240 250
RPKTFKSLEN AIEWSVKSGQ IRNLESARVS MVGQVKQCEG ITSPEGSKSI
260 270 280 290 300
VEGIIEEEEE DEEGSESISK RKKEDDMETK KDHPYTWRIE LAKTEKYWDG
310 320 330 340 350
WFRGLSNLFL SCPIPKLLLL AGVDRLDKDL TIGQMQGKFQ MQVLPQCGHA
360 370 380
VHEDAPDKVA EAVATFLIRH RFAEPIGGFQ CVFPGC
Length:386
Mass (Da):42,315
Last modified:January 9, 2013 - v2
Checksum:i37B25324583E8578
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABGA01002656 Genomic DNA No translation available.
ABGA01002657 Genomic DNA No translation available.
ABGA01002658 Genomic DNA No translation available.
ABGA01002659 Genomic DNA No translation available.
ABGA01002660 Genomic DNA No translation available.
ABGA01002661 Genomic DNA No translation available.
ABGA01002662 Genomic DNA No translation available.
NDHI03003437 Genomic DNA Translation: PNJ51347.1

Genome annotation databases

EnsembliENSPPYT00000004367; ENSPPYP00000004196; ENSPPYG00000003671

Similar proteinsi

Entry informationi

Entry nameiH2NEM5_PONAB
AccessioniPrimary (citable) accession number: H2NEM5
Secondary accession number(s): A0A2J8V1E4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: January 9, 2013
Last modified: May 23, 2018
This is version 42 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health