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Protein

Glutathione S-transferase

Gene

GSTM5

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferaseUniRule annotation (EC:2.5.1.18UniRule annotation)
Gene namesi
Name:GSTM5Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
Proteomesi
  • UP000001595 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000001233

Structurei

3D structure databases

ProteinModelPortaliH2N6H1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 88GST N-terminalInterPro annotationAdd BLAST88
Domaini90 – 207GST C-terminalInterPro annotationAdd BLAST118

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili97 – 117Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the GST superfamily. Mu family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IN5J Eukaryota
ENOG4110YU0 LUCA
GeneTreeiENSGT00550000074559
InParanoidiH2N6H1
KOiK00799
OrthoDBiEOG091G0K2E
TreeFamiTF353040

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR003081 GST_mu
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00043 GST_C, 1 hit
PF02798 GST_N, 1 hit
PRINTSiPR01267 GSTRNSFRASEM
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

H2N6H1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPMTLGYWDI RGLAHAIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK
60 70 80 90 100
FKLGLDFPNL PYLIDGTHKI TQSNAILRYI SRKHNLCGET EEEKIRVDML
110 120 130 140 150
ENQLMDSRME LVRLCNDPDF EKLKPKYLEE LPEKLKLYSE FLGKRPWFAG
160 170 180 190 200
DKITFVDFLA YDVLDVKRIF EPKCLDAFPN LKDFISRFEG LKKISAYMKS
210
SQFFRGLLFG KSATWNSK
Length:218
Mass (Da):25,730
Last modified:March 21, 2012 - v1
Checksum:i4063624782E6DEC4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABGA01031504 Genomic DNA No translation available.
RefSeqiXP_002810526.1, XM_002810480.3

Genome annotation databases

EnsembliENSPPYT00000001274; ENSPPYP00000001233; ENSPPYG00000001062
GeneIDi100453263
KEGGipon:100453263

Similar proteinsi

Entry informationi

Entry nameiH2N6H1_PONAB
AccessioniPrimary (citable) accession number: H2N6H1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: April 25, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health