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H2N4D1

- H2N4D1_PONAB

UniProt

H2N4D1 - H2N4D1_PONAB

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Protein
Submitted name: Uncharacterized protein
Gene
PTGS2
Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. heme binding Source: Ensembl
  2. peroxidase activity Source: InterPro
  3. prostaglandin-endoperoxide synthase activity Source: Ensembl

GO - Biological processi

  1. anagen Source: Ensembl
  2. brown fat cell differentiation Source: Ensembl
  3. cellular response to hypoxia Source: Ensembl
  4. cyclooxygenase pathway Source: Ensembl
  5. positive regulation of brown fat cell differentiation Source: Ensembl
  6. positive regulation of fever generation Source: Ensembl
  7. regulation of blood pressure Source: Ensembl
  8. regulation of cell proliferation Source: Ensembl
  9. response to oxidative stress Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:PTGS2Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
ProteomesiUP000001595: Chromosome 1

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. neuron projection Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000010743.
KOiK11987.
OrthoDBiEOG7RFTHC.
TreeFamiTF329675.

Family and domain databases

Gene3Di1.10.640.10. 1 hit.
InterProiIPR029576. COX-2.
IPR000742. EG-like_dom.
IPR010255. Haem_peroxidase.
IPR019791. Haem_peroxidase_animal.
[Graphical view]
PANTHERiPTHR11903:SF8. PTHR11903:SF8. 1 hit.
PfamiPF03098. An_peroxidase. 1 hit.
[Graphical view]
PRINTSiPR00457. ANPEROXIDASE.
SMARTiSM00181. EGF. 1 hit.
[Graphical view]
SUPFAMiSSF48113. SSF48113. 1 hit.
PROSITEiPS50026. EGF_3. 1 hit.
PS50292. PEROXIDASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H2N4D1-1 [UniParc]FASTAAdd to Basket

« Hide

MLARALLLCA VLALSHAANP CCSHPCQNRG VCMSVGFEQY KCDCTRTGFY    50
GENCSTPEFL TRIKLFLKPT PNTVHYILTH FKGFWNVVNN IPFLRNAIMS 100
YVLTSRSHLI DSPPTYNADY GYKSWEAFSN LSYYTRALPP VPDDCPTPLG 150
VKGKKQLPDS NEIVEKFLLR RKFIPDPQGT NMMFAFFAQH FTHQFFKSDH 200
KRGPAFTNGL GHGVDLNHIY GETLDRQHKL RLFKDGKMKY QIIDGEMYPP 250
TVKDTQAEMI YPPQVPEHLR FAVGQEVFGL VPGLMMYATI WLREHNRVCD 300
VLKQEHPEWG DEQLFQTSRL ILIGETIKIV IEDYVQHLSG YHFKLKFDPE 350
LLFNKQFQYQ NRIAAEFNTL YHWHPLLPDT FQIHDQKYNY QQFIYNNSIL 400
LEHGITQFVE SFTRQIAGRV AGGRNVPPAV QKVSQASIDQ SRQMKYQSFN 450
EYRKRFMLKP YESFEELTGE KEMSAELEAL YGDIDAMELY PGLLVEKPRP 500
DAIFGETMVE VGAPFSLKGL MGNVICSPAY WKPSTFGGEV GFQIINTASI 550
QSLICNNVKG CPFTSFSVPD PELIKTVTIN ASSSRSGLDD INPTVLLKER 600
STEL 604
Length:604
Mass (Da):69,057
Last modified:March 21, 2012 - v1
Checksum:i2E9980A4FD490561
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ABGA01049796 Genomic DNA. No translation available.
RefSeqiXP_002809734.1. XM_002809688.2.

Genome annotation databases

EnsembliENSPPYT00000000482; ENSPPYP00000000462; ENSPPYG00000000408.
GeneIDi100436566.
KEGGipon:100436566.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ABGA01049796 Genomic DNA. No translation available.
RefSeqi XP_002809734.1. XM_002809688.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSPPYT00000000482 ; ENSPPYP00000000462 ; ENSPPYG00000000408 .
GeneIDi 100436566.
KEGGi pon:100436566.

Organism-specific databases

CTDi 5743.

Phylogenomic databases

GeneTreei ENSGT00390000010743.
KOi K11987.
OrthoDBi EOG7RFTHC.
TreeFami TF329675.

Family and domain databases

Gene3Di 1.10.640.10. 1 hit.
InterProi IPR029576. COX-2.
IPR000742. EG-like_dom.
IPR010255. Haem_peroxidase.
IPR019791. Haem_peroxidase_animal.
[Graphical view ]
PANTHERi PTHR11903:SF8. PTHR11903:SF8. 1 hit.
Pfami PF03098. An_peroxidase. 1 hit.
[Graphical view ]
PRINTSi PR00457. ANPEROXIDASE.
SMARTi SM00181. EGF. 1 hit.
[Graphical view ]
SUPFAMi SSF48113. SSF48113. 1 hit.
PROSITEi PS50026. EGF_3. 1 hit.
PS50292. PEROXIDASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome."
    Wilson R.K., Mardis E.
    Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiH2N4D1_PONAB
AccessioniPrimary (citable) accession number: H2N4D1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: September 3, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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