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Protein

Alpha-amylase

Gene

LOC101163630

Organism
Oryzias latipes (Japanese rice fish) (Japanese killifish)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi115CalciumCombined sources1
Metal bindingi173Calcium; via carbonyl oxygenCombined sources1
Metal bindingi182CalciumCombined sources1
Metal bindingi216Calcium; via carbonyl oxygenCombined sources1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase
Biological processCarbohydrate metabolismUniRule annotationSAAS annotation
LigandCalciumCombined sources, Metal-bindingCombined sources

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseUniRule annotationSAAS annotation (EC:3.2.1.1UniRule annotationSAAS annotation)
Gene namesi
Name:LOC101163630Imported
OrganismiOryzias latipes (Japanese rice fish) (Japanese killifish)Imported
Taxonomic identifieri8090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeBeloniformesAdrianichthyidaeOryziinaeOryzias
Proteomesi
  • UP000001038 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_501299449316 – 512Alpha-amylaseSequence analysisAdd BLAST497

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi43 ↔ 101Combined sources
Disulfide bondi85 ↔ 130Combined sources
Disulfide bondi156 ↔ 175Combined sources
Disulfide bondi394 ↔ 400Combined sources
Disulfide bondi466 ↔ 478Combined sources

Interactioni

Protein-protein interaction databases

STRINGi8090.ENSORLP00000024837

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3VM5X-ray2.85A16-512[»]
SMRiH2N0D4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 414AamyInterPro annotationAdd BLAST389
Domaini423 – 511Aamy_CInterPro annotationAdd BLAST89

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2212 Eukaryota
COG0366 LUCA
GeneTreeiENSGT00390000002882
InParanoidiH2N0D4
KOiK01176
OMAiHPWWEVY
OrthoDBiEOG091G07V6
TreeFamiTF312850

Family and domain databases

Gene3Di2.60.40.1180, 1 hit
InterProiView protein in InterPro
IPR006048 A-amylase/branching_C
IPR031319 A-amylase_C
IPR006046 Alpha_amylase
IPR006047 Glyco_hydro_13_cat_dom
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF02806 Alpha-amylase_C, 1 hit
PRINTSiPR00110 ALPHAAMYLASE
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SM00632 Aamy_C, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit

Sequencei

Sequence statusi: Complete.

H2N0D4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLFVLIALF GLGFAQHNPN TRDGRTAIVH LFEWRWADIA AECERFLGPK
60 70 80 90 100
GFAGVQISPP NEHILVSSPW RPWWQRYQPI SYNLCSRSGG ENELRDMITR
110 120 130 140 150
CNNVGVNVYV DAVINHMCGA GGGEGTHSSC GSWFNANNKD FPSVPYSNLD
160 170 180 190 200
FNDGKCKTGS GNIENYGDPY QVRDCRLVGL LDLALEKDYV RGKVADFMNK
210 220 230 240 250
LIDMGVAGFR VDACKHMWPG DLDNVYRRLN NLNTKWFPGG SRPFIFQEVI
260 270 280 290 300
DLGGEPITTG EYVGLGRVTE FKYGARLGEL FRKWNGQKLS YTKNWGEGWG
310 320 330 340 350
FMADGNAVVF TDNHDNQRGH GAGGASILTF WDPRLYKMAV GYMLAHPYGF
360 370 380 390 400
TRVMSSYSWD RNFVNGKDEN DWIGPPSNGD GSTKPVPINP DQTCGDGWVC
410 420 430 440 450
EHRWRQIMNM VQFRNVVNGQ PHANWWDNGN NQVAFGRGNR GFIVFNNDDW
460 470 480 490 500
ALDVTLNTGL PGGTYCDVIS GNKDGGSCTG KQITVGGDGR AHFYINNSEE
510
DPFIAIHADS KL
Length:512
Mass (Da):57,167
Last modified:March 21, 2012 - v1
Checksum:iFFDA8EFC8F527D02
GO

Sequence databases

RefSeqiXP_004085115.1, XM_004085067.2

Genome annotation databases

EnsembliENSORLT00000024838; ENSORLP00000024837; ENSORLG00000020006
GeneIDi101163630
KEGGiola:101163630

Similar proteinsi

Entry informationi

Entry nameiH2N0D4_ORYLA
AccessioniPrimary (citable) accession number: H2N0D4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: March 28, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

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