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Protein

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

Gene

SHJG_5257

Organism
Streptomyces hygroscopicus subsp. jinggangensis (strain 5008)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Cofactori

(R)-lipoateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.-UniRule annotation)
Gene namesi
Ordered Locus Names:SHJG_5257Imported
OrganismiStreptomyces hygroscopicus subsp. jinggangensis (strain 5008)Imported
Taxonomic identifieri1133850 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000007170 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi1133850.SHJG_5257.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 84Lipoyl-bindingInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Keywords - Domaini

LipoylUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4107RN0. Bacteria.
COG0508. LUCA.
KOiK00627.
OMAiKHYYNIG.
OrthoDBiPOG091H05OF.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H2K5J0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTMTEASVR EFKMPDVGEG LTEAEILKWY VQPGDTVTDG QVVCEVETAK
60 70 80 90 100
AAVELPIPYD GVVRELHFPE GTTVDVGTPI IAVAVAGAGG AAPKAPAEQP
110 120 130 140 150
AAAPAPAKDE PKPEGRQPVL VGYGVAASST RRRPRKGPEV TVPAPAQAVQ
160 170 180 190 200
AELNGHGGAV AGKSRPLAKP PVRKLAKDLG VDLAAITPSG PDGIITREDV
210 220 230 240 250
HAAATPRTAE PAAPVTAAPA APAAPAPVAS YDTAREIRIP VKGVRKATAQ
260 270 280 290 300
AMVGSAFTAP HVTEFVTVDV TRTMKLVEEL KQDKEMQGLR VNPLLLIAKA
310 320 330 340 350
LLVAIKRNPD INASWDEANQ EIVRKRYVNL GIAAATPRGL IVPNIKDAQD
360 370 380 390 400
KTLPELAQAL GELVSTAREG KTSPAAMQGG TVTITNVGVF GVDTGTPILN
410 420 430 440 450
PGESAILAVG AIKLQPWVHK GKVKPRQVTT LALSFDHRLV DGELGSKVLA
460
DVAAVLEQPK RLITWA
Length:466
Mass (Da):48,623
Last modified:March 21, 2012 - v1
Checksum:iBDE231BE6C80F70F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003275 Genomic DNA. Translation: AEY90525.1.
RefSeqiWP_014673839.1. NC_017765.1.

Genome annotation databases

EnsemblBacteriaiAEY90525; AEY90525; SHJG_5257.
GeneIDi12805143.
KEGGishy:SHJG_5257.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003275 Genomic DNA. Translation: AEY90525.1.
RefSeqiWP_014673839.1. NC_017765.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi1133850.SHJG_5257.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEY90525; AEY90525; SHJG_5257.
GeneIDi12805143.
KEGGishy:SHJG_5257.

Phylogenomic databases

eggNOGiENOG4107RN0. Bacteria.
COG0508. LUCA.
KOiK00627.
OMAiKHYYNIG.
OrthoDBiPOG091H05OF.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiH2K5J0_STRHJ
AccessioniPrimary (citable) accession number: H2K5J0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: November 30, 2016
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.