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Protein

Glutamate decarboxylase

Gene

SHJG_5522

Organism
Streptomyces hygroscopicus subsp. jinggangensis (strain 5008)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciSHYG1133850:GLLU-5569-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:SHJG_5522Imported
OrganismiStreptomyces hygroscopicus subsp. jinggangensis (strain 5008)Imported
Taxonomic identifieri1133850 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
ProteomesiUP000007170 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

KOiK01580.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

H2JM56-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALHRGPDKH EERTMSVNPF FGEANPVGGM TEAPPTHRLP DAALPPSTAY
60 70 80 90 100
QLVHDELMLD GNSRLNLATF VTTWMEPQAG VLMDECRDKN MIDKDEYPRT
110 120 130 140 150
AELERRCVAM LADLWNAPDP SAAVGCSTTG SSEACMLAGM ALKRRWAKRN
160 170 180 190 200
ADRYPGARPN LVMGVNVQVC WEKFCTFWEV EARTVPMEGD RFHLDPQAAA
210 220 230 240 250
ELCDENTIGV VGILGSTFDG SYEPVADLCA ALDALQERTG LDIPVHVDGA
260 270 280 290 300
SGGMVAPFLD EDLVWDFRLP RVASINTSGH KYGLVYPGVG WALWRDKEAL
310 320 330 340 350
PEELVFRVNY LGGDMPTFAL NFSRPGAQVV AQYYTFLRLG REGYRAVQQS
360 370 380 390 400
TRDVATSLAS RIEALGDFRL LTRGDQLPVF ALTTADHVTS YDVFDVSRRL
410 420 430 440 450
REGGWLVPAY TFPANREDLS VLRIVCRNGF SHDLADLFLD DLARLLPELR
460
RQPHPLTRDK EAATGFHH
Length:468
Mass (Da):52,029
Last modified:March 21, 2012 - v1
Checksum:iDA649017ABB956DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003275 Genomic DNA. Translation: AEY90789.1.
RefSeqiYP_006246662.1. NC_017765.1.

Genome annotation databases

EnsemblBacteriaiAEY90789; AEY90789; SHJG_5522.
KEGGishy:SHJG_5522.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003275 Genomic DNA. Translation: AEY90789.1.
RefSeqiYP_006246662.1. NC_017765.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEY90789; AEY90789; SHJG_5522.
KEGGishy:SHJG_5522.

Phylogenomic databases

KOiK01580.

Enzyme and pathway databases

BioCyciSHYG1133850:GLLU-5569-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genomic analysis of Streptomyces hygroscopicus subsp. jinggangensis 5008."
    Wu H., Bai L.
    Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 5008Imported.

Entry informationi

Entry nameiH2JM56_STRHJ
AccessioniPrimary (citable) accession number: H2JM56
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: April 1, 2015
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.