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H2J7A6

- H2J7A6_MARPK

UniProt

H2J7A6 - H2J7A6_MARPK

Protein

Elongation factor Tu

Gene

tuf

Organism
Marinitoga piezophila (strain DSM 14283 / JCM 11233 / KA3)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (21 Mar 2012)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi81 – 855GTPUniRule annotation
    Nucleotide bindingi136 – 1394GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMPIE443254:GI5V-882-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    Ordered Locus Names:Marpi_0882Imported
    OrganismiMarinitoga piezophila (strain DSM 14283 / JCM 11233 / KA3)Imported
    Taxonomic identifieri443254 [NCBI]
    Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeMarinitoga
    ProteomesiUP000007161: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    KOiK02358.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    H2J7A6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKEKFVRSK PHMNIGTIGH IDHGKTTLTA AITKSLALKG YADFTPFEQI    50
    DKAPEEKQRG ITINIAHVEY ETDHRHYAHI DCPGHADYIK NMITGAAQMD 100
    GAILVVAATD GVMPQTREHV LLSRQVNVPA IVVFINKTDM VDDEEIIELV 150
    EMEVRELLNQ YEFPGDEVPV IKGSALKALE ADSQDDPWVQ KIYELMDAVD 200
    SYFPEPQRPV DQPFLMPVED VFSITGRGTV VTGRIERGAI HPGDEVEIVG 250
    MTDEIKKTVV TGVEMFRKLL DEGIAGDNVG CLLRGIDKDE VWRGQVLAKP 300
    GSITPHKKFK AQIYVLKKEE GGRHTPFKKG YRPQFYIRTA DVTGTLLEFE 350
    GGAEMVMPGD NIVTTVELIY PVALEKNMRF AVREGGRTVG AGVVTEIVE 399
    Length:399
    Mass (Da):44,311
    Last modified:March 21, 2012 - v1
    Checksum:i306CBBCBE330F25B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003257 Genomic DNA. Translation: AEX85298.1.
    RefSeqiWP_014296370.1. NC_016751.1.
    YP_005096596.1. NC_016751.1.

    Genome annotation databases

    EnsemblBacteriaiAEX85298; AEX85298; Marpi_0882.
    GeneIDi11603126.
    KEGGimpz:Marpi_0882.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003257 Genomic DNA. Translation: AEX85298.1 .
    RefSeqi WP_014296370.1. NC_016751.1.
    YP_005096596.1. NC_016751.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEX85298 ; AEX85298 ; Marpi_0882 .
    GeneIDi 11603126.
    KEGGi mpz:Marpi_0882.

    Phylogenomic databases

    KOi K02358.

    Enzyme and pathway databases

    BioCyci MPIE443254:GI5V-882-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Marinitoga piezophila KA3."
      Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Jebbar M.
      , Vannier P., Oger P., Cario A., Bartlett D., Noll K.M., Woyke T.
      Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 14283 / JCM 11233 / KA3Imported.

    Entry informationi

    Entry nameiH2J7A6_MARPK
    AccessioniPrimary (citable) accession number: H2J7A6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 21, 2012
    Last sequence update: March 21, 2012
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3