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H2I6M1 (H2I6M1_CORDV) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Phosphoserine aminotransferase EMBL AEX82939.1
EC=2.6.1.52 EMBL AEX82939.1
Gene names
Name:serC EMBL AEX82939.1
Ordered Locus Names:CDVA01_0670 EMBL AEX82939.1
OrganismCorynebacterium diphtheriae (strain VA01) [Complete proteome] [HAMAP] EMBL AEX82939.1
Taxonomic identifier698971 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium ›

Protein attributes

Sequence length376 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine By similarity. SAAS SAAS022278

Catalytic activity

4-phosphonooxy-L-threonine + 2-oxoglutarate = (3R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + L-glutamate. SAAS SAAS022278

O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate. SAAS SAAS022278

Cofactor

Binds 1 pyridoxal phosphate per subunit By similarity. SAAS SAAS022278

Pathway

Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3. SAAS SAAS022278

Subunit structure

Homodimer By similarity. SAAS SAAS022278

Subcellular location

Cytoplasm By similarity SAAS SAAS022278.

Sequences

Sequence LengthMass (Da)Tools
H2I6M1 [UniParc].

Last modified March 21, 2012. Version 1.
Checksum: D42C88B21851316E

FASTA37640,069
        10         20         30         40         50         60 
MSEYPILPST LIPADPRFGC GPSKVRPAQL NAIVNAGADV IGTSHRQPAV KNIVGSIREG 

        70         80         90        100        110        120 
LSSLFSLPDG YEIVLSLGGA TAFWDAATFG LIEKKSGHLT FGEFSGKFAK ASAQAPWLDE 

       130        140        150        160        170        180 
PTIISAEPGD TPTPVAMEGC DVIAWAHNET STGAMVPVIR PENSDGQLVA IDATSGAGGL 

       190        200        210        220        230        240 
PVDMHNADVY YFSPQKCFAS DGGLWLAAMS PAALERIEKI NASDRFIPAF LNLQTAVDNS 

       250        260        270        280        290        300 
RKNQTYNTPA VGTLLMLENQ VEWMNANGGL DAMVERTTAN SSALYEWAEK RAETTPYVTD 

       310        320        330        340        350        360 
PAKRSLVVGT IDFDDSIDAA ALAKVLRANG ILDVEPYRKL GRNQLRIGMF PAIDTADVDT 

       370 
LTAAIDYVLD NGFAQA

« Hide

References

[1]"Pangenomic Study of Corynebacterium diphtheriae That Provides Insights into the Genomic Diversity of Pathogenic Isolates from Cases of Classical Diphtheria, Endocarditis, and Pneumonia."
Trost E., Blom J., de Castro Soares S., Huang I.H., Al-Dilaimi A., Schroder J., Jaenicke S., Dorella F.A., Rocha F.S., Miyoshi A., Azevedo V., Schneider M.P., Silva A., Camello T.C., Sabbadini P.S., Santos C.S., Santos L.S., Hirata R.Jr. expand/collapse author list , Mattos-Guaraldi A.L., Efstratiou A., Schmitt M.P., Ton-That H., Tauch A.
J. Bacteriol. 194:3199-3215(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: VA01 EMBL AEX82939.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003217 Genomic DNA. Translation: AEX82939.1.
RefSeqYP_005144579.1. NC_016790.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEX82939; AEX82939; CDVA01_0670.
GeneID11719162.
KEGGcdv:CDVA01_0670.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00831.

Enzyme and pathway databases

BioCycCDIP698971:GHYD-692-MONOMER.
UniPathwayUPA00135; UER00197.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProIPR000192. Aminotrans_V/Cys_dSase.
IPR022278. Pser_aminoTfrase.
IPR006272. Pser_aminoTfrase_mycobac.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERPTHR21152:SF8. PTHR21152:SF8. 1 hit.
PfamPF00266. Aminotran_5. 1 hit.
[Graphical view]
PIRSFPIRSF000525. SerC. 1 hit.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR01366. serC_3. 1 hit.
ProtoNetSearch...

Entry information

Entry nameH2I6M1_CORDV
AccessionPrimary (citable) accession number: H2I6M1
Entry history
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: May 29, 2013
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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