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H2I5B7 (H2I5B7_CORDV) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS001608

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site341Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2611Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1341Substrate By similarity HAMAP-Rule MF_01201
Binding site3091Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue341N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
H2I5B7 [UniParc].

Last modified March 21, 2012. Version 1.
Checksum: 33AE57F1B1D9235A

FASTA38241,337
        10         20         30         40         50         60 
MNLLETRISC EAIAANTRRL KDMVAPAQLM CVVKADGYNH GAPEVATVMA RNGADQFGVA 

        70         80         90        100        110        120 
TLAEAHQLRD AGITLPILCW IWSPEQDFSA AIDRDIDLAA VSMEHVRALI AEAMRRPAGT 

       130        140        150        160        170        180 
RVRVTVKIDT ELHRSGIDEA NWTEAFELLH ACPQINVTGV FSHLACADDL ESDYTDHQAE 

       190        200        210        220        230        240 
VFRRAIDAGR RVGLDLSVNH LAASPATLTR PDLHFDMVRP GLALYGHEPI AGLDHGLREA 

       250        260        270        280        290        300 
MTWIGSVTVV KPIAAGQGTS YNMTWHAPAD GYLCVVPVGY ADGLPRNVQG HLEVTIAGTR 

       310        320        330        340        350        360 
YPQVGRVCMD QIVVFLGDNS RGVAPGDEAI IFGPRDTQAM TVTELACATG TINYEILCRP 

       370        380 
TGRSHRTYSA LDAVAPTHPT ES 

« Hide

References

[1]"Pangenomic Study of Corynebacterium diphtheriae That Provides Insights into the Genomic Diversity of Pathogenic Isolates from Cases of Classical Diphtheria, Endocarditis, and Pneumonia."
Trost E., Blom J., de Castro Soares S., Huang I.H., Al-Dilaimi A., Schroder J., Jaenicke S., Dorella F.A., Rocha F.S., Miyoshi A., Azevedo V., Schneider M.P., Silva A., Camello T.C., Sabbadini P.S., Santos C.S., Santos L.S., Hirata R.Jr. expand/collapse author list , Mattos-Guaraldi A.L., Efstratiou A., Schmitt M.P., Ton-That H., Tauch A.
J. Bacteriol. 194:3199-3215(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: VA01 EMBL AEX82723.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003217 Genomic DNA. Translation: AEX82723.1.
RefSeqYP_005144363.1. NC_016790.1.

3D structure databases

ProteinModelPortalH2I5B7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEX82723; AEX82723; CDVA01_0454.
GeneID11718942.
KEGGcdv:CDVA01_0454.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycCDIP698971:GHYD-472-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameH2I5B7_CORDV
AccessionPrimary (citable) accession number: H2I5B7
Entry history
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: July 9, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)