H2HYU8 (H2HYU8_CORDW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pseudouridine synthase RuleBase RU003887
EC=5.4.99.- RuleBase RU003887

Gene names

Ordered Locus Names:

CDPW8_1174 EMBL AEX69829.1

Organism

Corynebacterium diphtheriae (strain PW8) [Complete proteome] [HAMAP] EMBL AEX69829.1

Taxonomic identifier

698964 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium › Corynebacterium diphtheriae

Protein attributes

Sequence length	321 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the pseudouridine synthase rsuA family. RuleBase RU003887 Contains 1 S4 RNA-binding domain. SAAS SAAS006145

Ontologies

Keywords
Ligand	RNA-binding SAAS SAAS006145
Molecular function	Isomerase SAAS SAAS006145 RuleBase RU003887
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pseudouridine synthesis Inferred from electronic annotation. Source: InterPro
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW pseudouridine synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	H2HYU8 [UniParc]. Last modified March 21, 2012. Version 1. Checksum: 074033AD11D77483	FASTA	321	35,645
	10 20 30 40 50 60 MNRTARRDGT PEKPRRGSQG GFRGDYGKPK RSHAKPQSAN SDRPIKQRKQ RDSEMLISNA 70 80 90 100 110 120 RPARHQHVGR REAGDGSTEG IRLQKVLAQA GVASRRHAEI LIDAGRVEVN GKIVMTQGMR 130 140 150 160 170 180 VNPNVDVIRV DGVRVNVNEN LQYFVLNKPR GLQSTMSDDM GRPCVGDIVG ERISAGQRLF 190 200 210 220 230 240 HVGRLDAATE GLLLLTNDGE LANRLMHPRY EVSKTYLVTV LGEADKRLVK QLRDGIELDD 250 260 270 280 290 300 GPAKADLVQI IDTFQGKSLI RIELHEGRKH IVRRMLKTAG FPVQRLVRTK IHTIQLGEQT 310 320 PGAIRALNSS ELASLYKAVG M

References

[1]

"Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia." Trost E., Blom J., de Castro Soares S., Huang I.H., Al-Dilaimi A., Schroder J., Jaenicke S., Dorella F.A., Rocha F.S., Miyoshi A., Azevedo V., Schneider M.P., Silva A., Camello T.C., Sabbadini P.S., Santos C.S., Santos L.S., Hirata R. Jr. , Mattos-Guaraldi A.L., Efstratiou A., Schmitt M.P., Ton-That H., Tauch A. J. Bacteriol. 194:3199-3215(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PW8.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003216 Genomic DNA. Translation: AEX69829.1.
RefSeq	YP_005142734.1. NC_016789.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEX69829; AEX69829; CDPW8_1174.
GeneID	11716522.
KEGG	cdw:CDPW8_1174.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K06178.
Family and domain databases
Gene3D	3.10.290.10. 1 hit.
InterPro	IPR020103. PsdUridine_synth_cat_dom. IPR000748. PsdUridine_synth_RsuA/RluB/E/F. IPR018496. PsdUridine_synth_RsuA/RluB_CS. IPR006145. PsdUridine_synth_RsuA/RluD. IPR002942. S4_RNA-bd. [Graphical view]
Pfam	PF00849. PseudoU_synth_2. 1 hit. PF01479. S4. 1 hit. [Graphical view]
SMART	SM00363. S4. 1 hit. [Graphical view]
SUPFAM	SSF55120. PsdUridine_synth_cat_dom. 1 hit.
TIGRFAMs	TIGR00093. TIGR00093. 1 hit.
PROSITE	PS01149. PSI_RSU. 1 hit. PS50889. S4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

H2HYU8_CORDW

Accession

Primary (citable) accession number: H2HYU8

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2012
Last sequence update:	March 21, 2012
Last modified:	April 3, 2013
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)