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H2HC70

- H2HC70_CORDH

UniProt

H2HC70 - H2HC70_CORDH

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Protein
Submitted name:

Alanine aminotransferase

Gene

alaT

Organism
Corynebacterium diphtheriae (strain HC01)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. L-alanine:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Enzyme and pathway databases

BioCyciCDIP698967:GHQ6-2096-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Alanine aminotransferaseImported (EC:2.6.1.2Imported)
Gene namesi
Name:alaTImported
Ordered Locus Names:CDHC01_2038Imported
OrganismiCorynebacterium diphtheriae (strain HC01)Imported
Taxonomic identifieri698967 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000007157: Chromosome

Structurei

3D structure databases

ProteinModelPortaliH2HC70.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK14260.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

H2HC70 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MNNKKETPQA APAQRKRTRR IFDQSDKLKN VLYEIRGPVT AEAEAMELDG
60 70 80 90 100
HRILKLNTGN PAIFGFEAPD VIMRDMIASL PTSQGYSTSK GIIPARRAIV
110 120 130 140 150
TRYEVIPGFP AFDVDDVYIG NGVSELITMT TQALLNNGDE VLIPMPDYPL
160 170 180 190 200
WTAATSLAGG KPVHYLCDEE DDWNPSIEDI KSKITERTKA IVVINPNNPT
210 220 230 240 250
GAVYSKEVLQ KIVDVAREHD LLILADEIYD RILYDGAVHT NIAALAPDLL
260 270 280 290 300
CITFNGLSKA YRVAGYRAGW MIVTGPKNNA RGFIEGLDLL SGTRLCANVP
310 320 330 340 350
GQHAIQVALG GRQSIYDLTG QGGRLLEQRN VTWEKLNAIP GVSCVKPMGA
360 370 380 390 400
LYAFPKLDLE YYDIKDDAQL MLDLLRQEKI LMVQGTGFNW DKPDHFRVVT
410 420
LPWASQLSEA MDRLGNFLAS YKQ
Length:423
Mass (Da):46,909
Last modified:March 21, 2012 - v1
Checksum:iBD8FD73B6CF0EA58
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003212 Genomic DNA. Translation: AEX75279.1.
RefSeqiYP_005136827.1. NC_016786.1.

Genome annotation databases

EnsemblBacteriaiAEX75279; AEX75279; CDHC01_2038.
GeneIDi11708059.
KEGGicdt:CDHC01_2038.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003212 Genomic DNA. Translation: AEX75279.1 .
RefSeqi YP_005136827.1. NC_016786.1.

3D structure databases

ProteinModelPortali H2HC70.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEX75279 ; AEX75279 ; CDHC01_2038 .
GeneIDi 11708059.
KEGGi cdt:CDHC01_2038.

Phylogenomic databases

KOi K14260.

Enzyme and pathway databases

BioCyci CDIP698967:GHQ6-2096-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProi IPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
Pfami PF00155. Aminotran_1_2. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia."
    Trost E., Blom J., de Castro Soares S., Huang I.H., Al-Dilaimi A., Schroder J., Jaenicke S., Dorella F.A., Rocha F.S., Miyoshi A., Azevedo V., Schneider M.P., Silva A., Camello T.C., Sabbadini P.S., Santos C.S., Santos L.S., Hirata R. Jr.
    , Mattos-Guaraldi A.L., Efstratiou A., Schmitt M.P., Ton-That H., Tauch A.
    J. Bacteriol. 194:3199-3215(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HC01Imported.

Entry informationi

Entry nameiH2HC70_CORDH
AccessioniPrimary (citable) accession number: H2HC70
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 1, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3