Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

H2H669

- H2H669_CORDD

UniProt

H2H669 - H2H669_CORDD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Corynebacterium diphtheriae (strain CDCE 8392)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei147 – 1471UniRule annotation
Active sitei576 – 5761UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciCDIP698965:GHJP-1049-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:CDCE8392_1024Imported
OrganismiCorynebacterium diphtheriae (strain CDCE 8392)Imported
Taxonomic identifieri698965 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000007156: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

H2H669-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGTLCIHHFC RKAELVTAAI SDRVREDIRL LGRVLGRVIV QQEGEEVYEL
60 70 80 90 100
VEATRRMAFD VFHGDADPED LMVIFRDLDI TKTNLVARAF SYFALLANLA
110 120 130 140 150
EDLDDESVEA DVSLRKTFAK LKQEGVSAAD AASVIRSAEV APVLTAHPTE
160 170 180 190 200
TRRRTVFDTQ TRIKQLLKDA HHGGDMQVIE QEMYLRMTLL WQTALIRIAR
210 220 230 240 250
PTLEDEIDVG LRYYKKSLLE QVPALNRSIR HSMRETFGLQ LPDIAVMRPG
260 270 280 290 300
SWIGGDHDGN PYVNARTLTY ATRQAAKTVA RYYVEQLGEL ERELSLSDRY
310 320 330 340 350
SSCSKELLAL AEASGNNWES RVDEPYRRAV YGMRARMKSN VDALERPEKT
360 370 380 390 400
AGKKSSKRTP YATPEEFLRD LDVIDRSLRA HNDDVIADDR LARIRSAVTT
410 420 430 440 450
FGFHLYTLDI RQNSESFEAV IEEVFAAARR VPGGKRYSEL AETEKVELLI
460 470 480 490 500
QELQTPRPLL FPGALEVEDA FSADTTKELG IFLAAAQAVR DFGSRSIAHC
510 520 530 540 550
IISMTATVSD ILEPMVLLKE VGLRDVDVVP LFETIDDLRC GAAILRELWS
560 570 580 590 600
HPFYREHLRA RGDIQEVMLG YSDSNKDGGY LQANWALYDA ELGLVELCRE
610 620 630 640 650
HNIELRLAHG RGGAVGRGGG PTYDAILAQP KGAVSGSVRI TEQGEVISAK
660 670 680 690 700
YGAPETARRH LEAFVSGALE ASLLDTEPIA DPDRAYAIMR DLAGFSGQRY
710 720 730 740 750
QELVGDPGFI EYFTQSTPLH EIGELNLGSR PAARKQTTAI SDLRAIPWVL
760 770 780 790 800
SWSQSRTNIP GWFGVGSAVS RFVSAVPEKD RESRWQELRD LYATWPFFRS
810 820 830 840 850
VMSNMAQVMA KAEISLARLY ADLVDDPEVA DRIYALIAEE FELTRRAYLA
860 870 880 890 900
ITGNEALVSE NQRQARSLKR RYPYLLPLNA IQLELLRRYR GGDDQFLVSK
910
TIQVTMNGLA TALRNAG
Length:917
Mass (Da):102,829
Last modified:March 21, 2012 - v1
Checksum:iC01FB9F9BE95BD04
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003211 Genomic DNA. Translation: AEX72017.1.
RefSeqiYP_005133565.1. NC_016785.1.

Genome annotation databases

EnsemblBacteriaiAEX72017; AEX72017; CDCE8392_1024.
GeneIDi11705606.
KEGGicdd:CDCE8392_1024.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003211 Genomic DNA. Translation: AEX72017.1 .
RefSeqi YP_005133565.1. NC_016785.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEX72017 ; AEX72017 ; CDCE8392_1024 .
GeneIDi 11705606.
KEGGi cdd:CDCE8392_1024.

Phylogenomic databases

KOi K01595.

Enzyme and pathway databases

BioCyci CDIP698965:GHJP-1049-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia."
    Trost E., Blom J., de Castro Soares S., Huang I.H., Al-Dilaimi A., Schroder J., Jaenicke S., Dorella F.A., Rocha F.S., Miyoshi A., Azevedo V., Schneider M.P., Silva A., Camello T.C., Sabbadini P.S., Santos C.S., Santos L.S., Hirata R. Jr.
    , Mattos-Guaraldi A.L., Efstratiou A., Schmitt M.P., Ton-That H., Tauch A.
    J. Bacteriol. 194:3199-3215(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CDCE 8392Imported.

Entry informationi

Entry nameiH2H669_CORDD
AccessioniPrimary (citable) accession number: H2H669
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 29, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3