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Protein
Submitted name:

Sialidase-1

Gene

nanH

Organism
Corynebacterium diphtheriae (strain CDCE 8392)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
  2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
  3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Enzyme and pathway databases

BioCyciCDIP698965:GHJP-505-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase-1Imported (EC:3.2.1.18Imported)
Gene namesi
Name:nanHImported
Ordered Locus Names:CDCE8392_0488Imported
OrganismiCorynebacterium diphtheriae (strain CDCE 8392)Imported
Taxonomic identifieri698965 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000007156: Chromosome

Family & Domainsi

Phylogenomic databases

KOiK01186.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR026856. Sialidase_fam.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
SUPFAMiSSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Complete.

H2H3C3-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MQKPKHAIGH TLLGLTAAIS LTAQTLDTPV LAQEKSDLGT VQSPSIIPGG
60 70 80 90 100
AEVGLFDAAP PSEPVLGAAG GVGLPEAQTQ PVFEKKVIRD VDPSGQRCVR
110 120 130 140 150
IPAIVTAEDG SLLVAFDNRR GSGTNCPDAP FKVGNSKDPS LQTDIELYRS
160 170 180 190 200
TDSGKNFEKA GFIAQGTRDP RGLSYTDPAM VVDRTTGKIF AFFVRALDQR
210 220 230 240 250
VAQAGAGYHE GDAAGQINNR SVQDTIVIES NDDGQTWENM HLISHLTGQV
260 270 280 290 300
KVNGRTYQGR GRFVTSGSGI QLRYGEHAGR LIVPIAVDVE PSWSAKFVNL
310 320 330 340 350
AIYSDNGGET WEIGEGIAGD GARSGDENKL VELSDGTLMM NSKEFGGSTR
360 370 380 390 400
WTAYSTDQGL TWGNLKSTVF APPQHPSKFN EAINVGLIRA YPNAPQGSAA
410 420 430 440 450
AKVLLHSAPI EHRTSSDDGR RNGWVMASCD DGKTWKHGRQ IEEGRFLYSV
460 470 480 490 500
MTPMEDGTIG MAYESINSQG LIIKFAKFNM SWLGADCLSE KTTGIAPKLD
510 520 530 540 550
PKVVAKAEEA AKAALKADAK VQELVDKLGA SKANDVMLRQ ELAAAEADAA
560 570 580 590 600
KAHAAAEEAK AAVAQAEEAM RAAVEEMQVQ LDSMKEQAVK TEGEMAEQTA
610 620 630 640 650
ALEKAQQQLK EAGEKNAELQ AKLQEVETQL AESREKAAAL AQQAKEQSKV
660 670 680 690 700
VKDVTEQVVK EVPGDKEDAA VPAEKKGFSW ASLIGLLGMG LPILVAIFNA

VRQFLHI
Length:707
Mass (Da):75,557
Last modified:March 21, 2012 - v1
Checksum:i604597657F7863C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003211 Genomic DNA. Translation: AEX71488.1.
RefSeqiWP_014306516.1. NC_016785.1.
YP_005133036.1. NC_016785.1.

Genome annotation databases

EnsemblBacteriaiAEX71488; AEX71488; CDCE8392_0488.
GeneIDi11706934.
KEGGicdd:CDCE8392_0488.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003211 Genomic DNA. Translation: AEX71488.1.
RefSeqiWP_014306516.1. NC_016785.1.
YP_005133036.1. NC_016785.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEX71488; AEX71488; CDCE8392_0488.
GeneIDi11706934.
KEGGicdd:CDCE8392_0488.

Phylogenomic databases

KOiK01186.

Enzyme and pathway databases

BioCyciCDIP698965:GHJP-505-MONOMER.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR026856. Sialidase_fam.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
SUPFAMiSSF50939. SSF50939. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia."
    Trost E., Blom J., de Castro Soares S., Huang I.H., Al-Dilaimi A., Schroder J., Jaenicke S., Dorella F.A., Rocha F.S., Miyoshi A., Azevedo V., Schneider M.P., Silva A., Camello T.C., Sabbadini P.S., Santos C.S., Santos L.S., Hirata R. Jr.
    , Mattos-Guaraldi A.L., Efstratiou A., Schmitt M.P., Ton-That H., Tauch A.
    J. Bacteriol. 194:3199-3215(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CDCE 8392Imported.

Entry informationi

Entry nameiH2H3C3_CORDD
AccessioniPrimary (citable) accession number: H2H3C3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: January 7, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.