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H2GW18

- H2GW18_CORD7

UniProt

H2GW18 - H2GW18_CORD7

Protein
Submitted name:

Sialidase-1

Gene

nanH

Organism
Corynebacterium diphtheriae (strain ATCC 27012 / C7 (beta))
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (21 Mar 2012)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
    2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
    3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pathogenesis Source: InterPro

    Keywords - Molecular functioni

    GlycosidaseImported, Hydrolase

    Enzyme and pathway databases

    BioCyciCDIP698963:GHGE-516-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Sialidase-1Imported (EC:3.2.1.18Imported)
    Gene namesi
    Name:nanHImported
    Ordered Locus Names:CDC7B_0498Imported
    OrganismiCorynebacterium diphtheriae (strain ATCC 27012 / C7 (beta))Imported
    Taxonomic identifieri698963 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
    ProteomesiUP000007160: Chromosome

    Family & Domainsi

    Phylogenomic databases

    KOiK01186.
    OMAiQDTIVIE.

    Family and domain databases

    Gene3Di2.120.10.10. 1 hit.
    InterProiIPR026856. Sialidase_fam.
    IPR008377. Sialidase_trypan.
    IPR011040. Sialidases.
    [Graphical view]
    PANTHERiPTHR10628. PTHR10628. 1 hit.
    PTHR10628:SF5. PTHR10628:SF5. 1 hit.
    SUPFAMiSSF50939. SSF50939. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    H2GW18-1 [UniParc]FASTAAdd to Basket

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    MYSSNRTYSR AILGLSAVLT LSFTSLVAPV NAEEPETVVP ATAELEGEVA    50
    ATLPSAETGL FDAAPPKPVA RGAAGDLQLP AVNEKEVFEE GRVIRAPEPD 100
    QSRCYRIPAL VTAKNGDLLL AFDNRYGGGD GAKTWCRDAP YENMKRINRQ 150
    NMQTDIQLYR SVDNGQSFED FGYIAQGTAD VRELSYTDPA LVTDRTTGKI 200
    FAFFVRAYDY RVGQSSAGFN EGDVEAEIQK RDVQDTVVVE SLDGGQTWGN 250
    MRLLSALTAK VSSISTGDTI FDGRGRFVTS GAGIQLQYGE HAGRLIVPIS 300
    VDIDPKDSAK FINLAIYSDD HGQTWQAGIG TAGGAGFSGD ESKIVELSDG 350
    RLMMSSKDND KPRWVSYSED QGENWSTPKR KIIAPPQHPE KHNTGINVGL 400
    IRAYPNAPEN SAAARVLLYS APIDQRYSHK HTEDGRNNGW VMGSCDDGKT 450
    WSFGRQIEKN RFQYSSMTVM SDGNIGMVYE SGDFSTGMNL KFAKFNMAWL 500
    GADCLSNEAL GLTGDIDKEI VEAQEKAAEA TKEAQEAAEK VQKLTEELAA 550
    ARKENDELKN QVKGSKEAVG DLANEVEDLA DKVFKLETAV TEAKEKATVA 600
    EKAASDAVTQ LQKAESIAEE QKAKAESAAA EAQALREKLE RLEGSILTVK 650
    ENPEAEEIAD LSSTAKDAAD AARRAATDAN GALSGQKQDE EKPAMGLMGI 700
    LKVLAGIIPL VAIIATIFQT FRLPFNIPGM R 731
    Length:731
    Mass (Da):79,132
    Last modified:March 21, 2012 - v1
    Checksum:i505BA8F0B44FC8B3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003210 Genomic DNA. Translation: AEX66697.1.
    RefSeqiWP_014318693.1. NC_016801.1.
    YP_005161951.1. NC_016801.1.

    Genome annotation databases

    EnsemblBacteriaiAEX66697; AEX66697; CDC7B_0498.
    GeneIDi11736772.
    KEGGicds:CDC7B_0498.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003210 Genomic DNA. Translation: AEX66697.1 .
    RefSeqi WP_014318693.1. NC_016801.1.
    YP_005161951.1. NC_016801.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEX66697 ; AEX66697 ; CDC7B_0498 .
    GeneIDi 11736772.
    KEGGi cds:CDC7B_0498.

    Phylogenomic databases

    KOi K01186.
    OMAi QDTIVIE.

    Enzyme and pathway databases

    BioCyci CDIP698963:GHGE-516-MONOMER.

    Family and domain databases

    Gene3Di 2.120.10.10. 1 hit.
    InterProi IPR026856. Sialidase_fam.
    IPR008377. Sialidase_trypan.
    IPR011040. Sialidases.
    [Graphical view ]
    PANTHERi PTHR10628. PTHR10628. 1 hit.
    PTHR10628:SF5. PTHR10628:SF5. 1 hit.
    SUPFAMi SSF50939. SSF50939. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia."
      Trost E., Blom J., de Castro Soares S., Huang I.H., Al-Dilaimi A., Schroder J., Jaenicke S., Dorella F.A., Rocha F.S., Miyoshi A., Azevedo V., Schneider M.P., Silva A., Camello T.C., Sabbadini P.S., Santos C.S., Santos L.S., Hirata R. Jr.
      , Mattos-Guaraldi A.L., Efstratiou A., Schmitt M.P., Ton-That H., Tauch A.
      J. Bacteriol. 194:3199-3215(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 27012 / C7 (beta)Imported.

    Entry informationi

    Entry nameiH2GW18_CORD7
    AccessioniPrimary (citable) accession number: H2GW18
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 21, 2012
    Last sequence update: March 21, 2012
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3