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H2GW18

- H2GW18_CORD7

UniProt

H2GW18 - H2GW18_CORD7

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Protein
Submitted name:

Sialidase-1

Gene

nanH

Organism
Corynebacterium diphtheriae (strain ATCC 27012 / C7 (beta))
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
  2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
  3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC

GO - Biological processi

  1. pathogenesis Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Enzyme and pathway databases

BioCyciCDIP698963:GHGE-516-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase-1Imported (EC:3.2.1.18Imported)
Gene namesi
Name:nanHImported
Ordered Locus Names:CDC7B_0498Imported
OrganismiCorynebacterium diphtheriae (strain ATCC 27012 / C7 (beta))Imported
Taxonomic identifieri698963 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000007160: Chromosome

Family & Domainsi

Phylogenomic databases

KOiK01186.
OMAiQDTIVIE.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR026856. Sialidase_fam.
IPR008377. Sialidase_trypan.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PTHR10628:SF5. PTHR10628:SF5. 1 hit.
SUPFAMiSSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Complete.

H2GW18-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MYSSNRTYSR AILGLSAVLT LSFTSLVAPV NAEEPETVVP ATAELEGEVA
60 70 80 90 100
ATLPSAETGL FDAAPPKPVA RGAAGDLQLP AVNEKEVFEE GRVIRAPEPD
110 120 130 140 150
QSRCYRIPAL VTAKNGDLLL AFDNRYGGGD GAKTWCRDAP YENMKRINRQ
160 170 180 190 200
NMQTDIQLYR SVDNGQSFED FGYIAQGTAD VRELSYTDPA LVTDRTTGKI
210 220 230 240 250
FAFFVRAYDY RVGQSSAGFN EGDVEAEIQK RDVQDTVVVE SLDGGQTWGN
260 270 280 290 300
MRLLSALTAK VSSISTGDTI FDGRGRFVTS GAGIQLQYGE HAGRLIVPIS
310 320 330 340 350
VDIDPKDSAK FINLAIYSDD HGQTWQAGIG TAGGAGFSGD ESKIVELSDG
360 370 380 390 400
RLMMSSKDND KPRWVSYSED QGENWSTPKR KIIAPPQHPE KHNTGINVGL
410 420 430 440 450
IRAYPNAPEN SAAARVLLYS APIDQRYSHK HTEDGRNNGW VMGSCDDGKT
460 470 480 490 500
WSFGRQIEKN RFQYSSMTVM SDGNIGMVYE SGDFSTGMNL KFAKFNMAWL
510 520 530 540 550
GADCLSNEAL GLTGDIDKEI VEAQEKAAEA TKEAQEAAEK VQKLTEELAA
560 570 580 590 600
ARKENDELKN QVKGSKEAVG DLANEVEDLA DKVFKLETAV TEAKEKATVA
610 620 630 640 650
EKAASDAVTQ LQKAESIAEE QKAKAESAAA EAQALREKLE RLEGSILTVK
660 670 680 690 700
ENPEAEEIAD LSSTAKDAAD AARRAATDAN GALSGQKQDE EKPAMGLMGI
710 720 730
LKVLAGIIPL VAIIATIFQT FRLPFNIPGM R
Length:731
Mass (Da):79,132
Last modified:March 21, 2012 - v1
Checksum:i505BA8F0B44FC8B3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003210 Genomic DNA. Translation: AEX66697.1.
RefSeqiYP_005161951.1. NC_016801.1.

Genome annotation databases

EnsemblBacteriaiAEX66697; AEX66697; CDC7B_0498.
GeneIDi11736772.
KEGGicds:CDC7B_0498.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003210 Genomic DNA. Translation: AEX66697.1 .
RefSeqi YP_005161951.1. NC_016801.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEX66697 ; AEX66697 ; CDC7B_0498 .
GeneIDi 11736772.
KEGGi cds:CDC7B_0498.

Phylogenomic databases

KOi K01186.
OMAi QDTIVIE.

Enzyme and pathway databases

BioCyci CDIP698963:GHGE-516-MONOMER.

Family and domain databases

Gene3Di 2.120.10.10. 1 hit.
InterProi IPR026856. Sialidase_fam.
IPR008377. Sialidase_trypan.
IPR011040. Sialidases.
[Graphical view ]
PANTHERi PTHR10628. PTHR10628. 1 hit.
PTHR10628:SF5. PTHR10628:SF5. 1 hit.
SUPFAMi SSF50939. SSF50939. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia."
    Trost E., Blom J., de Castro Soares S., Huang I.H., Al-Dilaimi A., Schroder J., Jaenicke S., Dorella F.A., Rocha F.S., Miyoshi A., Azevedo V., Schneider M.P., Silva A., Camello T.C., Sabbadini P.S., Santos C.S., Santos L.S., Hirata R. Jr.
    , Mattos-Guaraldi A.L., Efstratiou A., Schmitt M.P., Ton-That H., Tauch A.
    J. Bacteriol. 194:3199-3215(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27012 / C7 (beta)Imported.

Entry informationi

Entry nameiH2GW18_CORD7
AccessioniPrimary (citable) accession number: H2GW18
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 29, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3