H2GVT4 (H2GVT4_CORD7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Deoxyguanosinetriphosphate triphosphohydrolase-like protein HAMAP-Rule MF_01212

Gene names

Name:	dgt EMBL AEX67879.1
Ordered Locus Names:	CDC7B_1686 EMBL AEX67879.1

Organism

Corynebacterium diphtheriae (strain ATCC 27012 / C7 (beta)) [Complete proteome] [HAMAP] EMBL AEX67879.1

Taxonomic identifier

698963 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium › Corynebacterium diphtheriae

Protein attributes

Sequence length	423 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dGTPase family. Type 2 subfamily. HAMAP-Rule MF_01212

Ontologies

Keywords
Molecular function	Hydrolase SAAS SAAS023293 HAMAP-Rule MF_01212 EMBL AEX67879.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	GTP metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	dGTPase activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	H2GVT4 [UniParc]. Last modified March 21, 2012. Version 1. Checksum: CC717BF7234EA552	FASTA	423	46,642
	10 20 30 40 50 60 MFSYSSSDWQ RRFDEPEKPS RIIAHHDERG PFAKDRARVL HSAALRRLAD KTQVVGPRDG 70 80 90 100 110 120 DTPRTRLTHS LEVAQIARGI GTGLGLDADL CEMAGLTHDI GHPPYGHNGE KALAEIAQDC 130 140 150 160 170 180 GGFEGNAQTL RILSKLEPKI VDDHDQSYGL NLTRAALDAA CKYPRTKTNP DGSVNKKYGC 190 200 210 220 230 240 YDEDAHILQW VRQGHEDTSA CVEAQAMDFS DDIAYSVHDV EDGIVSGRVH LGVLWDFVEL 250 260 270 280 290 300 AELAEKGARA FGGTPEALVD AADHLRELPI ISAAADFDGS LRGYVDLKAM TSQLVGRYVG 310 320 330 340 350 360 AVIEASRAAN PTGVFGRSTG QVVVPDQVLA EVTLLKTIAV LYVMDDPAHL QRQDRQRERI 370 380 390 400 410 420 YRVYDYLVAG GRGALDPMFR LWWEQAESEA QRQRVIIDNI SSMTESRLER VAKQSAELSS FMG

References

[1]

"Pangenomic Study of Corynebacterium diphtheriae That Provides Insights into the Genomic Diversity of Pathogenic Isolates from Cases of Classical Diphtheria, Endocarditis, and Pneumonia." Trost E., Blom J., de Castro Soares S., Huang I.H., Al-Dilaimi A., Schroder J., Jaenicke S., Dorella F.A., Rocha F.S., Miyoshi A., Azevedo V., Schneider M.P., Silva A., Camello T.C., Sabbadini P.S., Santos C.S., Santos L.S., Hirata R.Jr. , Mattos-Guaraldi A.L., Efstratiou A., Schmitt M.P., Ton-That H., Tauch A. J. Bacteriol. 194:3199-3215(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27012 / C7 (beta).

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003210 Genomic DNA. Translation: AEX67879.1.
RefSeq	YP_005163133.1. NC_016801.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEX67879; AEX67879; CDC7B_1686.
GeneID	11736042.
KEGG	cds:CDC7B_1686.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01129.
Enzyme and pathway databases
BioCyc	CDIP698963:GHGE-1730-MONOMER.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit. 1.10.3410.10. 1 hit.
HAMAP	MF_01212. dGTPase_type2.
InterPro	IPR006261. dGTP_triP_hydro. IPR023293. dGTP_triP_hydro_central. IPR023023. dGTP_triP_hydro_type2. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR026875. PHydrolase_assoc_dom. [Graphical view]
Pfam	PF01966. HD. 1 hit. PF13286. HD_assoc. 1 hit. [Graphical view]
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01353. dGTP_triPase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

H2GVT4_CORD7

Accession

Primary (citable) accession number: H2GVT4

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2012
Last sequence update:	March 21, 2012
Last modified:	May 29, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)