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Protein
Submitted name:

Sialidase-1

Gene

nanH

Organism
Corynebacterium diphtheriae (strain 241)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
  2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
  3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC

GO - Biological processi

  1. pathogenesis Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase-1Imported (EC:3.2.1.18Imported)
Gene namesi
Name:nanHImported
Ordered Locus Names:CD241_0480Imported
OrganismiCorynebacterium diphtheriae (strain 241)Imported
Taxonomic identifieri698966 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000007868: Chromosome

Family & Domainsi

Phylogenomic databases

KOiK01186.
OMAiRAYPNAP.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR026856. Sialidase_fam.
IPR008377. Sialidase_trypan.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PTHR10628:SF5. PTHR10628:SF5. 1 hit.
SUPFAMiSSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Complete.

H2GDZ9-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MYSSNRTYSR AILGLSAALA LSFTSLAVPA NAQESETALP ATAELNGKES
60 70 80 90 100
AALLSAETGL FDAAPPKPVA RGAAGNLQLP AVNEEEVFEE GRVIRAPEPD
110 120 130 140 150
QSRCYRIPAL VTAQNGDLLL AFDNRYGGGD GAKTWCRDAP YENMKRINRQ
160 170 180 190 200
NMQTDIQLYR SVDNGQSFED FGYIAQGTAD VRELSYTDPA LVTDRTTGKI
210 220 230 240 250
FAFFVRAYDY RVGQSSAGFN EGDVEAEIQK RDVQDTVVVE SLDGGQTWGN
260 270 280 290 300
MRLLSALTAK VSSISTGDTI FDGRGRFVTS GAGIQLQYGE HAGRLIVPIS
310 320 330 340 350
VDIDPKDSAK FINLAIYSDD HGQTWQAGIG TAGGAGFSGD ESKIVELSDG
360 370 380 390 400
RLMMSSKDND KPRWVSYSED QGENWSTPKR KIIAPPQHPE KHNTGINVGL
410 420 430 440 450
IRAYPNAPEN SAAARVLLYS APIDQRYSHK HTEDGRNNGW VMGSCDDGKT
460 470 480 490 500
WSFGRQIEKN RFQYSSMTVM SDGNIGMVYE SGDFSTGMNL KFAKFNMAWL
510 520 530 540 550
GADCLSNEAL GLTGDIDKEI VAAQEKAAAA TKEAQEAAEK VEKLTEELAA
560 570 580 590 600
ARKENDELKT QVKESEEAVG DLADKVFKLE NAVTEAKKKA TVAEKAVSDA
610 620 630 640 650
LAKLQEAESI AEEQKAKAES AAAEAQALRE KLEKVEGSIL IVKENSEAEE
660 670 680 690 700
SADLSSTVKD AADTARRAAT DANGALSGQK QNEEKPAMGL MRILKVLAGI
710 720
IPLVAIIATI FQTFHLPFNI PGMR
Length:724
Mass (Da):78,307
Last modified:March 21, 2012 - v1
Checksum:i45B68A17B381090D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003207 Genomic DNA. Translation: AEX43547.1.
RefSeqiYP_005124749.1. NC_016782.1.

Genome annotation databases

EnsemblBacteriaiAEX43547; AEX43547; CD241_0480.
GeneIDi11673458.
KEGGicdp:CD241_0480.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003207 Genomic DNA. Translation: AEX43547.1.
RefSeqiYP_005124749.1. NC_016782.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEX43547; AEX43547; CD241_0480.
GeneIDi11673458.
KEGGicdp:CD241_0480.

Phylogenomic databases

KOiK01186.
OMAiRAYPNAP.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR026856. Sialidase_fam.
IPR008377. Sialidase_trypan.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PTHR10628:SF5. PTHR10628:SF5. 1 hit.
SUPFAMiSSF50939. SSF50939. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia."
    Trost E., Blom J., de Castro Soares S., Huang I.H., Al-Dilaimi A., Schroder J., Jaenicke S., Dorella F.A., Rocha F.S., Miyoshi A., Azevedo V., Schneider M.P., Silva A., Camello T.C., Sabbadini P.S., Santos C.S., Santos L.S., Hirata R. Jr.
    , Mattos-Guaraldi A.L., Efstratiou A., Schmitt M.P., Ton-That H., Tauch A.
    J. Bacteriol. 194:3199-3215(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 241Imported.

Entry informationi

Entry nameiH2GDZ9_CORD2
AccessioniPrimary (citable) accession number: H2GDZ9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: February 4, 2015
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.