H2G1D1 (H2G1D1_OCESG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Isocitrate dehydrogenase, NADP-dependent EMBL AEX99823.1

Gene names

Ordered Locus Names:

GU3_00335 EMBL AEX99823.1

Organism

Oceanimonas sp. (strain GK1) [Complete proteome] [HAMAP] EMBL AEX99823.1

Taxonomic identifier

511062 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Oceanimonas

Protein attributes

Sequence length	743 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Ontologies

Keywords
Ligand	Magnesium PIRSR PIRSR009407-3 Metal-binding PIRSR PIRSR009407-3
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	isocitrate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Region	134 – 141	8	Substrate binding By similarity PIRSR PIRSR009407-2
Sites
	Metal binding	351	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Metal binding	549	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Metal binding	553	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Binding site	147	1	Substrate By similarity PIRSR PIRSR009407-2
	Binding site	548	1	Substrate By similarity PIRSR PIRSR009407-2
	Site	256	1	Critical for catalysis By similarity PIRSR PIRSR009407-1
	Site	421	1	Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

	Sequence		Length	Mass (Da)
	H2G1D1 [UniParc]. Last modified March 21, 2012. Version 1. Checksum: 91323AD118B672FA	FASTA	743	82,090
	10 20 30 40 50 60 MTNKTSTIVY TLTDEAPALA TYSLLPIIRT FTDAAGIDVT LSDISLAGRV LAAFPERLTD 70 80 90 100 110 120 EQRVADGLAE LGKLTQDPHA NIIKLPNISA SVPQLRACIK ELQSQGYNVP DFPEEPKTDE 130 140 150 160 170 180 DKAIREAYSK ILGSAVNPVL RQGNSDRRAP AAVKAFARKY PHSMGAWSKA SRSHADYMNG 190 200 210 220 230 240 GDFFSSEQSV TMDKAQTVRI EFIGQDGKPQ LKKELALQAG EVLDSMFMSA KALEAFFEQT 250 260 270 280 290 300 LQDCKDAGVM WSLHVKATMM KVSHPIVFGH AVKVFYKEVF DKYGKLFEEL GVNPNNGMSS 310 320 330 340 350 360 VLEKIKTLPQ STQEEIEQAI HDCYEHRPEM AMVDSVKGIT NLHVPSDVIV DASMPAMIRN 370 380 390 400 410 420 SGQMWGRDGK LKDTKAVMPE STYARIYQEV INFCKTNGAF DPRTMGSVSN VGLMAMKAEE 430 440 450 460 470 480 YGSHDKTFEM TENGTMRVVN EAGEVLMQHE VEKGDIWRAC QTKDAAIRDW VKLAVNRARN 490 500 510 520 530 540 SATPAVFWLD DERAHDNELR KKVNTYLQEH DLTGLDIHIM SYNEAIRFSM ERMKRGKDTI 550 560 570 580 590 600 SVTGNVLRDY LTDLFPIMEL GTSAKMLSIV PMLAGGGMYE TGAGGSAPKH VQQLMEENHL 610 620 630 640 650 660 RWDSLGEFLA LAVSLEELGI KEGNDRAKLL AKCLDKATEL LLDNGKSPSR RAGELDNRGS 670 680 690 700 710 720 HFYLALYWAQ ELAAQTEDEA LAAHFAPLAK ALADNEAKIV AELNAVQGKS AGVHGYYHAS 730 740 PAELEQVMRP SATLNQTLAQ LNG

References

[1]

"Complete genome sequence of Oceanimonas sp. GK1, a halotolerant bacterium from Gavkhouni Wetland in Iran." Parsa Yeganeh L., Azarbaijani R., Sarikhan S., Mousavi H., Ramezani M., Amoozegar M.A., Shahzadeh Fazeli A., Salekdeh G.H. J. Bacteriol. 194:2123-2124(2012) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GK1 EMBL AEX99823.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003171 Genomic DNA. Translation: AEX99823.1.
RefSeq	YP_005090574.1. NC_016745.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEX99823; AEX99823; GU3_00335.
GeneID	11597160.
KEGG	oce:GU3_00335.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K00031.
Family and domain databases
Gene3D	3.40.718.10. 3 hits.
InterPro	IPR004436. Isocitrate_DH_NADP_mono. IPR024084. IsoPropMal-DH-like_dom. [Graphical view]
Pfam	PF03971. IDH. 1 hit. [Graphical view]
PIRSF	PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMs	TIGR00178. monomer_idh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

H2G1D1_OCESG

Accession

Primary (citable) accession number: H2G1D1

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2012
Last sequence update:	March 21, 2012
Last modified:	April 3, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)