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H2G1D1

- H2G1D1_OCESG

UniProt

H2G1D1 - H2G1D1_OCESG

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Protein
Submitted name: Isocitrate dehydrogenase, NADP-dependent
Gene
GU3_00335
Organism
Oceanimonas sp. (strain GK1)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei147 – 1471Substrate By similarityUniRule annotation
Sitei256 – 2561Critical for catalysis By similarity
Metal bindingi351 – 3511Magnesium or manganese By similarityUniRule annotation
Sitei421 – 4211Critical for catalysis By similarityUniRule annotation
Binding sitei548 – 5481Substrate By similarityUniRule annotation
Metal bindingi549 – 5491Magnesium or manganese By similarityUniRule annotation
Metal bindingi553 – 5531Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciOSP511062:GI6E-68-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported
Gene namesi
Ordered Locus Names:GU3_00335Imported
OrganismiOceanimonas sp. (strain GK1)Imported
Taxonomic identifieri511062 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeOceanimonas
ProteomesiUP000007742: Chromosome

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni134 – 1418Substrate binding By similarityUniRule annotation

Phylogenomic databases

KOiK00031.
OMAiSIVKLMQ.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

H2G1D1-1 [UniParc]FASTAAdd to Basket

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MTNKTSTIVY TLTDEAPALA TYSLLPIIRT FTDAAGIDVT LSDISLAGRV    50
LAAFPERLTD EQRVADGLAE LGKLTQDPHA NIIKLPNISA SVPQLRACIK 100
ELQSQGYNVP DFPEEPKTDE DKAIREAYSK ILGSAVNPVL RQGNSDRRAP 150
AAVKAFARKY PHSMGAWSKA SRSHADYMNG GDFFSSEQSV TMDKAQTVRI 200
EFIGQDGKPQ LKKELALQAG EVLDSMFMSA KALEAFFEQT LQDCKDAGVM 250
WSLHVKATMM KVSHPIVFGH AVKVFYKEVF DKYGKLFEEL GVNPNNGMSS 300
VLEKIKTLPQ STQEEIEQAI HDCYEHRPEM AMVDSVKGIT NLHVPSDVIV 350
DASMPAMIRN SGQMWGRDGK LKDTKAVMPE STYARIYQEV INFCKTNGAF 400
DPRTMGSVSN VGLMAMKAEE YGSHDKTFEM TENGTMRVVN EAGEVLMQHE 450
VEKGDIWRAC QTKDAAIRDW VKLAVNRARN SATPAVFWLD DERAHDNELR 500
KKVNTYLQEH DLTGLDIHIM SYNEAIRFSM ERMKRGKDTI SVTGNVLRDY 550
LTDLFPIMEL GTSAKMLSIV PMLAGGGMYE TGAGGSAPKH VQQLMEENHL 600
RWDSLGEFLA LAVSLEELGI KEGNDRAKLL AKCLDKATEL LLDNGKSPSR 650
RAGELDNRGS HFYLALYWAQ ELAAQTEDEA LAAHFAPLAK ALADNEAKIV 700
AELNAVQGKS AGVHGYYHAS PAELEQVMRP SATLNQTLAQ LNG 743
Length:743
Mass (Da):82,090
Last modified:March 21, 2012 - v1
Checksum:i91323AD118B672FA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003171 Genomic DNA. Translation: AEX99823.1.
RefSeqiWP_014290560.1. NC_016745.1.
YP_005090574.1. NC_016745.1.

Genome annotation databases

EnsemblBacteriaiAEX99823; AEX99823; GU3_00335.
GeneIDi11597160.
KEGGioce:GU3_00335.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003171 Genomic DNA. Translation: AEX99823.1 .
RefSeqi WP_014290560.1. NC_016745.1.
YP_005090574.1. NC_016745.1.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEX99823 ; AEX99823 ; GU3_00335 .
GeneIDi 11597160.
KEGGi oce:GU3_00335.

Phylogenomic databases

KOi K00031.
OMAi SIVKLMQ.

Enzyme and pathway databases

BioCyci OSP511062:GI6E-68-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Oceanimonas sp. GK1, a halotolerant bacterium from Gavkhouni Wetland in Iran."
    Parsa Yeganeh L., Azarbaijani R., Sarikhan S., Mousavi H., Ramezani M., Amoozegar M.A., Shahzadeh Fazeli A., Salekdeh G.H.
    J. Bacteriol. 194:2123-2124(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GK1Imported.

Entry informationi

Entry nameiH2G1D1_OCESG
AccessioniPrimary (citable) accession number: H2G1D1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: September 3, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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