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H2G1D1

- H2G1D1_OCESG

UniProt

H2G1D1 - H2G1D1_OCESG

Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

GU3_00335

Organism
Oceanimonas sp. (strain GK1)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (21 Mar 2012)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei147 – 1471Substrate
    Sitei256 – 2561Critical for catalysisUniRule annotation
    Metal bindingi351 – 3511Magnesium or manganeseUniRule annotation
    Sitei421 – 4211Critical for catalysisUniRule annotation
    Binding sitei548 – 5481Substrate
    Metal bindingi549 – 5491Magnesium or manganeseUniRule annotation
    Metal bindingi553 – 5531Magnesium or manganeseUniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciOSP511062:GI6E-68-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase, NADP-dependentImported
    Gene namesi
    Ordered Locus Names:GU3_00335Imported
    OrganismiOceanimonas sp. (strain GK1)Imported
    Taxonomic identifieri511062 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeOceanimonas
    ProteomesiUP000007742: Chromosome

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni134 – 1418Substrate bindingUniRule annotation

    Phylogenomic databases

    KOiK00031.
    OMAiSIVKLMQ.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    H2G1D1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTNKTSTIVY TLTDEAPALA TYSLLPIIRT FTDAAGIDVT LSDISLAGRV    50
    LAAFPERLTD EQRVADGLAE LGKLTQDPHA NIIKLPNISA SVPQLRACIK 100
    ELQSQGYNVP DFPEEPKTDE DKAIREAYSK ILGSAVNPVL RQGNSDRRAP 150
    AAVKAFARKY PHSMGAWSKA SRSHADYMNG GDFFSSEQSV TMDKAQTVRI 200
    EFIGQDGKPQ LKKELALQAG EVLDSMFMSA KALEAFFEQT LQDCKDAGVM 250
    WSLHVKATMM KVSHPIVFGH AVKVFYKEVF DKYGKLFEEL GVNPNNGMSS 300
    VLEKIKTLPQ STQEEIEQAI HDCYEHRPEM AMVDSVKGIT NLHVPSDVIV 350
    DASMPAMIRN SGQMWGRDGK LKDTKAVMPE STYARIYQEV INFCKTNGAF 400
    DPRTMGSVSN VGLMAMKAEE YGSHDKTFEM TENGTMRVVN EAGEVLMQHE 450
    VEKGDIWRAC QTKDAAIRDW VKLAVNRARN SATPAVFWLD DERAHDNELR 500
    KKVNTYLQEH DLTGLDIHIM SYNEAIRFSM ERMKRGKDTI SVTGNVLRDY 550
    LTDLFPIMEL GTSAKMLSIV PMLAGGGMYE TGAGGSAPKH VQQLMEENHL 600
    RWDSLGEFLA LAVSLEELGI KEGNDRAKLL AKCLDKATEL LLDNGKSPSR 650
    RAGELDNRGS HFYLALYWAQ ELAAQTEDEA LAAHFAPLAK ALADNEAKIV 700
    AELNAVQGKS AGVHGYYHAS PAELEQVMRP SATLNQTLAQ LNG 743
    Length:743
    Mass (Da):82,090
    Last modified:March 21, 2012 - v1
    Checksum:i91323AD118B672FA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003171 Genomic DNA. Translation: AEX99823.1.
    RefSeqiWP_014290560.1. NC_016745.1.
    YP_005090574.1. NC_016745.1.

    Genome annotation databases

    EnsemblBacteriaiAEX99823; AEX99823; GU3_00335.
    GeneIDi11597160.
    KEGGioce:GU3_00335.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003171 Genomic DNA. Translation: AEX99823.1 .
    RefSeqi WP_014290560.1. NC_016745.1.
    YP_005090574.1. NC_016745.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEX99823 ; AEX99823 ; GU3_00335 .
    GeneIDi 11597160.
    KEGGi oce:GU3_00335.

    Phylogenomic databases

    KOi K00031.
    OMAi SIVKLMQ.

    Enzyme and pathway databases

    BioCyci OSP511062:GI6E-68-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Oceanimonas sp. GK1, a halotolerant bacterium from Gavkhouni Wetland in Iran."
      Parsa Yeganeh L., Azarbaijani R., Sarikhan S., Mousavi H., Ramezani M., Amoozegar M.A., Shahzadeh Fazeli A., Salekdeh G.H.
      J. Bacteriol. 194:2123-2124(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GK1Imported.

    Entry informationi

    Entry nameiH2G1D1_OCESG
    AccessioniPrimary (citable) accession number: H2G1D1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 21, 2012
    Last sequence update: March 21, 2012
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3