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Protein

Phosphoglycerate mutase

Gene

KAFR0E01720

Organism
Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 / NRRL Y-8276) (Yeast) (Kluyveromyces africanus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

2-phospho-D-glycerate = 3-phospho-D-glycerate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 3 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Glyceraldehyde-3-phosphate dehydrogenase (KAFR0C06190), Glyceraldehyde-3-phosphate dehydrogenase (KAFR0E01870), Glyceraldehyde-3-phosphate dehydrogenase (KAFR0E01510)
  2. no protein annotated in this organism
  3. Phosphoglycerate mutase (KAFR0C00970), Phosphoglycerate mutase (KAFR0E01720)
  4. no protein annotated in this organism
  5. Pyruvate kinase (KAFR0K00510)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotation
Biological processGlycolysisUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00109; UER00186.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate mutaseUniRule annotation (EC:5.4.2.11UniRule annotation)
Gene namesi
Name:KAFR0E01720Imported
ORF Names:KAFR_0E01720Imported
OrganismiKazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 / NRRL Y-8276) (Yeast) (Kluyveromyces africanus)Imported
Taxonomic identifieri1071382 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKazachstania
Proteomesi
  • UP000005220 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Structurei

3D structure databases

ProteinModelPortaliH2AVC6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.UniRule annotation

Phylogenomic databases

InParanoidiH2AVC6.
KOiK01834.
OrthoDBiEOG092C4JJL.

Family and domain databases

CDDicd07067. HP_PGM_like. 1 hit.
Gene3Di3.40.50.1240. 1 hit.
HAMAPiMF_01039. PGAM_GpmA. 1 hit.
InterProiView protein in InterPro
IPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR001345. PG/BPGM_mutase_AS.
IPR005952. Phosphogly_mut1.
PANTHERiPTHR11931. PTHR11931. 1 hit.
PfamiView protein in Pfam
PF00300. His_Phos_1. 1 hit.
SMARTiView protein in SMART
SM00855. PGAM. 1 hit.
SUPFAMiSSF53254. SSF53254. 1 hit.
TIGRFAMsiTIGR01258. pgm_1. 1 hit.
PROSITEiView protein in PROSITE
PS00175. PG_MUTASE. 1 hit.

Sequencei

Sequence statusi: Complete.

H2AVC6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKLVLVRHG QSEWNEKNLF TGWVDVRLSA IGEKEAARAG ELLKEKNVMP
60 70 80 90 100
DVLYTSKLSR AIQTANIALS KADRLWIPVN RSWRLNERHY GALQGKDKAA
110 120 130 140 150
TLEQYGEEKF TTWRRSYDVP PPPIEDDSEF SQKNDVRYKD VDPNVLPATE
160 170 180 190 200
SLALVIDRLL PYWQDVISKD LLEGKTVMIA AHGNSLRGLV KHLEGISDAD
210 220 230 240
IAKLNIPTGI PLVFELDENL KPSKPSYYLD PEAAAAGAAA VAAQGKKK
Length:248
Mass (Da):27,658
Last modified:March 21, 2012 - v1
Checksum:iE75BB48F84B636C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE650825 Genomic DNA. Translation: CCF58326.1.
RefSeqiXP_003957461.1. XM_003957412.1.

Genome annotation databases

EnsemblFungiiCCF58326; CCF58326; KAFR_0E01720.
GeneIDi13882905.
KEGGikaf:KAFR_0E01720.

Similar proteinsi

Entry informationi

Entry nameiH2AVC6_KAZAF
AccessioniPrimary (citable) accession number: H2AVC6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: June 7, 2017
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported