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H2AQL1

- H2AQL1_KAZAF

UniProt

H2AQL1 - H2AQL1_KAZAF

Protein

Glutamate decarboxylase

Gene

KAFR0B03640

Organism
Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 / NRRL Y-8276) (Yeast) (Kluyveromyces africanus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 15 (01 Oct 2014)
      Sequence version 1 (21 Mar 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Name:KAFR0B03640Imported
    ORF Names:KAFR_0B03640Imported
    OrganismiKazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 / NRRL Y-8276) (Yeast) (Kluyveromyces africanus)Imported
    Taxonomic identifieri1071382 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKazachstania
    ProteomesiUP000005220: Chromosome 2

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    KOiK01580.
    OrthoDBiEOG7P2Z22.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    H2AQL1-1 [UniParc]FASTAAdd to Basket

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    MLHRHSAKHR NPRTVFTHKK SDLPPESKLL SYQEQELEKG KLSGVESVDD    50
    ARPTLANKYK IPKQGIEEKY AYQLVHNELT LDGNPHLNLA SFVNTYSTDE 100
    AKRLITENLN KNLADNDEYP QLIEITQRCI SILSQLWHCD ENMEPMGCST 150
    TGSSEAIMLG GLAMKKNWVK KMEKAGKPID KPNIVMSCAC QVALEKFARY 200
    FDVECRLVPV SAKSHHMLDP SLLHEYVDEN TIGLFVIMGT TYTGHLEDVE 250
    DVSNTLTKLE KEHPEWSNTQ IPIHVDGASG GFIVPFAFEN SHMKEFGLER 300
    WAFNNPRVVS INTSSHKFGL TTPGLGWVLW KDEAYLPQEL RFRLKYLGGV 350
    EETFGLNFSR PGFQVVHQYF NFISKGAAGY RETFRRSLFV ARVFSHGLLT 400
    SNKLKGCFDI VSSIHEKITD SSTPKGVNEY WESPSLFKPG VPLVAFKLTK 450
    EFQAEYSEIP QVLISSMLRA RGWIIPNYPL PKSTDESDKD EVLRVVFRHE 500
    MKLDLAQLLL FDIEMVMQRL VNSYRRVCMH VDKKLTESDE SKGLRRSFIY 550
    DMLLTLASPE GEEISEGDLN AKEDELNKKH KKKQEIRERT SRNYRGTC 598
    Length:598
    Mass (Da):68,409
    Last modified:March 21, 2012 - v1
    Checksum:i41BB2166061BD43A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE650822 Genomic DNA. Translation: CCF56661.1.
    RefSeqiXP_003955796.1. XM_003955747.1.

    Genome annotation databases

    GeneIDi13883121.
    KEGGikaf:KAFR_0B03640.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE650822 Genomic DNA. Translation: CCF56661.1 .
    RefSeqi XP_003955796.1. XM_003955747.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 13883121.
    KEGGi kaf:KAFR_0B03640.

    Phylogenomic databases

    KOi K01580.
    OrthoDBi EOG7P2Z22.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Evolutionary erosion of yeast sex chromosomes by mating-type switching accidents."
      Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P., Wolfe K.H.
      Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 / NRRL Y-8276Imported.

    Entry informationi

    Entry nameiH2AQL1_KAZAF
    AccessioniPrimary (citable) accession number: H2AQL1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 21, 2012
    Last sequence update: March 21, 2012
    Last modified: October 1, 2014
    This is version 15 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3