SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

H2AM14

- NSS_SBVBH

UniProt

H2AM14 - NSS_SBVBH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Non-structural protein NS-S
Gene
N
Organism
Bovine Schmallenberg virus (isolate Bovine/BH80/Germany/2011) (SBV)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Plays a role in the inhibition of the host immune response by intefering with the production of interferon in infected cells.1 Publication

GO - Biological processi

  1. viral process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein NS-S
Gene namesi
Name:N
OrganismiBovine Schmallenberg virus (isolate Bovine/BH80/Germany/2011) (SBV)
Taxonomic identifieri1318464 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesBunyaviridaeOrthobunyavirusunclassified Orthobunyavirus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 9191Non-structural protein NS-S
PRO_0000422474Add
BLAST

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi34 – 374Poly-Ser

Sequence similaritiesi

Family and domain databases

InterProiIPR000797. Bunya_NSs.
[Graphical view]
PfamiPF01104. Bunya_NS-S. 1 hit.
[Graphical view]
PIRSFiPIRSF003954. NS-S_OrthobunV. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative initiation. Align

Isoform NSS (identifier: H2AM14-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MYHNGMQLHL TRRSGMWHLL VSMGNNSTSV LLESSSSTRR RPRWSYIRRH   50
NQVSILLLVG SNLQWLITIF PNMSQILCQT MPLHFTGCQD I 91

Note: Produced by alternative initiation in the N gene, but encoded on another frame.

Length:91
Mass (Da):10,598
Last modified:March 21, 2012 - v1
Checksum:iB2A97F19CD8EBFDB
GO
Isoform N (identifier: H2AM13-1) [UniParc]FASTAAdd to Basket

The sequence of this isoform can be found in the external entry H2AM13.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:233
Mass (Da):26,181
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
JX853181 Viral cRNA. Translation: AGC84163.1.
KC139379 Viral cRNA. Translation: AGD94637.1.
KC139380 Viral cRNA. Translation: AGD94639.1.
KC139381 Viral cRNA. Translation: AGD94641.1.
HE649914 Genomic RNA. Translation: CCF55032.1.

Keywords - Coding sequence diversityi

Alternative initiation

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
JX853181 Viral cRNA. Translation: AGC84163.1 .
KC139379 Viral cRNA. Translation: AGD94637.1 .
KC139380 Viral cRNA. Translation: AGD94639.1 .
KC139381 Viral cRNA. Translation: AGD94641.1 .
HE649914 Genomic RNA. Translation: CCF55032.1 .

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR000797. Bunya_NSs.
[Graphical view ]
Pfami PF01104. Bunya_NS-S. 1 hit.
[Graphical view ]
PIRSFi PIRSF003954. NS-S_OrthobunV. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    Strain: BH80/11-4.
  2. Hoeper D.
    Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    Strain: BH80/11-4.
  3. "In vivo and in vitro identification of a hypervariable region in Schmallenberg virus."
    Coupeau D., Claine F., Wiggers L., Kirschvink N., Muylkens B.
    J. Gen. Virol. 94:1168-1174(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    Strain: Na2.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA], FUNCTION.
    Strain: Germany.

Entry informationi

Entry nameiNSS_SBVBH
AccessioniPrimary (citable) accession number: H2AM14
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2013
Last sequence update: March 21, 2012
Last modified: October 16, 2013
This is version 10 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi