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H2AEX1 (H2AEX1_BACAM) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate dehydratase HAMAP-Rule MF_00214
Short name=3-dehydroquinase HAMAP-Rule MF_00214
EC=4.2.1.10 HAMAP-Rule MF_00214
Alternative name(s):
Type I DHQase HAMAP-Rule MF_00214
Gene names
Name:aroD HAMAP-Rule MF_00214 EMBL CCF04313.1
ORF Names:BACAU_0779 EMBL CCF04313.1
OrganismBacillus amyloliquefaciens subsp. plantarum CAU B946 EMBL CCF04313.1
Taxonomic identifier1114958 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus ›

Protein attributes

Sequence length253 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-dehydroquinate = 3-dehydroshikimate + H2O. HAMAP-Rule MF_00214

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7. HAMAP-Rule MF_00214

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00214

Sequence similarities

Belongs to the type-I 3-dehydroquinase family. HAMAP-Rule MF_00214

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region46 – 483Substrate binding By similarity HAMAP-Rule MF_00214

Sites

Active site1431Proton donor/acceptor By similarity HAMAP-Rule MF_00214
Active site1701Schiff-base intermediate with substrate By similarity HAMAP-Rule MF_00214
Binding site821Substrate By similarity HAMAP-Rule MF_00214
Binding site2131Substrate By similarity HAMAP-Rule MF_00214
Binding site2321Substrate By similarity HAMAP-Rule MF_00214
Binding site2361Substrate By similarity HAMAP-Rule MF_00214

Sequences

Sequence LengthMass (Da)Tools
H2AEX1 [UniParc].

Last modified March 21, 2012. Version 1.
Checksum: F4B34D9824465A31

FASTA25327,980
        10         20         30         40         50         60 
MQSITIRNTV IGEGLPKIIV PLMAAGEKEL LEEIEAVNRL RPDIIEWRAD VYEHVDSLDA 

        70         80         90        100        110        120 
VKGMLEKLRK AAGATPLLFT FRTHKEGGNK VIDDRFYIEL LKTAIETKHI DLADVELFTG 

       130        140        150        160        170        180 
EAEVKSIVKT AEDNGVYVVM SNHDFHQTPK KEEIISRLRN MQAYGAHIPK IAVMPQSTED 

       190        200        210        220        230        240 
VFVLLDATHT MKTQYADRPI ITMSMAGTGL ISRLAGEVFG SACTFGAGKE ASAPGQIPVE 

       250 
ELRSVLSILN KHI

« Hide

References

[1]"The Complete Genome of Bacillus amyloliquefaciens subsp. plantarum CAU B946 Contains a Gene Cluster for Nonribosomal Synthesis of Iturin A."
Blom J., Rueckert C., Niu B., Wang Q., Borriss R.
J. Bacteriol. 194:1845-1846(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: CAU B946 EMBL CCF04313.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		HE617159 Genomic DNA. Translation: CCF04313.1.
RefSeqYP_005129508.1. NC_016784.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCF04313; CCF04313; BACAU_0779.
GeneID11697275.
KEGGbaq:BACAU_0779.

Phylogenomic databases

KOK03785.

Enzyme and pathway databases

UniPathwayUPA00053; UER00086.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00214. AroD.
InterProIPR018508. 3-dehydroquinate_DH_AS.
IPR013785. Aldolase_TIM.
IPR001381. DHquinase_I.
[Graphical view]
PfamPF01487. DHquinase_I. 1 hit.
[Graphical view]
TIGRFAMsTIGR01093. aroD. 1 hit.
PROSITEPS01028. DEHYDROQUINASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameH2AEX1_BACAM
AccessionPrimary (citable) accession number: H2AEX1
Entry history
Integrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: May 1, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info