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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptococcus macedonicus (strain ACA-DC 198)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei138UniRule annotation1
Active sitei604UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:SMA_1525Imported
OrganismiStreptococcus macedonicus (strain ACA-DC 198)Imported
Taxonomic identifieri1116231 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000007152 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi1116231.SMA_1525.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiCOG2352. LUCA.
KOiK01595.
OMAiPWVFGWT.
OrthoDBiPOG091H040O.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiView protein in InterPro
IPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR018129. PEP_COase_Lys_AS.
IPR033129. PEPCASE_His_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
PfamiView protein in Pfam
PF00311. PEPcase. 1 hit.
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 2 hits.
PROSITEiView protein in PROSITE
PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

H2A7S4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTIKKLENNS TQSIITEEVK ILKGLLDEIT HQMVGDEVFA KIQNIVELSA
60 70 80 90 100
SDEYVKLEKL VVQLTNDEMV VVSRYFSILP LLINISEDVD FAYEINYQNN
110 120 130 140 150
TNQDYLGKLS LTVDMVSESE NSKEILENVN VVPVLTAHPT QVQRKTVLEL
160 170 180 190 200
TNHIHDLLRK YRDVRAGVVN RDKWYTDLRR YIEIIMQTDI IREKKLKVKN
210 220 230 240 250
EITNVMEYYN TSLIQAITKL TSEYKRLAAE KGIDLENPKP ITMGMWIGGD
260 270 280 290 300
RDGNPYVTAE TLRLSATVQS EVIINYYIEK LTALYRTFSL STTLTNISPE
310 320 330 340 350
VEKLAELSSD KSIYRENEPY RKAFNYIQSK LIQTLIELKA NTAISQGVLE
360 370 380 390 400
GSNNISSDVC TSTKNAGVIT KYLQTKFSKV SSELQEEIPS YKTAKEFKDD
410 420 430 440 450
LFIIKQSLLD NGDDALLTGD FSELLQAVDV FGFYLAMIDM RQDSSVNEAC
460 470 480 490 500
VAELLKSANI IEDYSSLSEE EKVKVLLKEL QEDPRTLSST NAEKSEQLQK
510 520 530 540 550
ELAIFQTARY LKDKLGDEVI KQHIISHTES VSDMFELAIM LKEVGLLDNQ
560 570 580 590 600
TARVQIVPLF ETIEDLENSR AIMEEYLDYD IVRRWVSASK GYQEIMLGYS
610 620 630 640 650
DSNKDGGYLS SVWTLYKAQN ELTRIGSERG IKVTFIHGRG GTVGRGGGPS
660 670 680 690 700
YEAITSQPFG SIKDRIRLTE QGEIIENKYG NKDVAYYNLE MLVSATIDRI
710 720 730 740 750
VTRMITNPDE IDDFRATMDG IVTYSNGVYR DLVFGNPHFY DYFFEATPIK
760 770 780 790 800
EVSSLNIGSR PAARKTITEI SGLRAIPWVF SWSQSRIMFP GWYGVGSAFK
810 820 830 840 850
NFIDAEEGNL AKLQHMYEKW PFFHSLLSNV DMVLSKSNMN IAFQYAQLAE
860 870 880 890 900
SEEVRDVFNT ILDEWQLTKN VILAIEKHQD LLEENPSLKA SLDYRLPYFN
910 920 930 940
VLNYIQIELI KRLRHEELDE DYEKLIHTTI NGIATGLRNS G
Length:941
Mass (Da):107,390
Last modified:March 21, 2012 - v1
Checksum:iD29E3CDA83B217B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE613569 Genomic DNA. Translation: CCF02816.1.
RefSeqiWP_014294971.1. NC_016749.1.

Genome annotation databases

EnsemblBacteriaiCCF02816; CCF02816; SMA_1525.
KEGGismn:SMA_1525.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiH2A7S4_STRMD
AccessioniPrimary (citable) accession number: H2A7S4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: June 7, 2017
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported